2. Metabolic Enzyme/Protease
  3. Cytochrome P450
  4. Desmethylcitalopram hydrochloride

Desmethylcitalopram hydrochloride  (Synonyms: DCIT hydrochloride)

製品番号: HY-113739 純度: 99.87%
COA 取扱説明書 Technical Support

Desmethylcitalopram (DCIT) hydrochloride is the active metabolite of Citalopram (HY-121203). Desmethylcitalopram has antidepressant effects. Desmethylcitalopram also inhibits cytochrome P450-2D6, -2C19 with IC50s of 39.5 and 53.5 μM.

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Desmethylcitalopram hydrochloride

Desmethylcitalopram hydrochloride 構造式

CAS 番号 : 97743-99-2

容量 価格（税別） 在庫状況 数量
1 mg $200 在庫あり
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10 mg   お問い合わせ  

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Other Forms of Desmethylcitalopram hydrochloride:

Desmethylcitalopram hydrochloride 関連抗体

Top Publications Citing Use of Products

Cytochrome P450 アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A CYP3A4 CYP17A1

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製品説明

Desmethylcitalopram (DCIT) hydrochloride is the active metabolite of Citalopram (HY-121203). Desmethylcitalopram has antidepressant effects. Desmethylcitalopram also inhibits cytochrome P450-2D6, -2C19 with IC50s of 39.5 and 53.5 μM[1].

臨床実験
分子量

346.83

分子式

C19H20ClFN2O
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

CNCCCC1(OCC2=CC(C#N)=CC=C21)C3=CC=C(C=C3)F.Cl
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Store at room temperature, keep dry and cool

*In solvent : -80°C, 6 months; -20°C, 1 month (Store at room temperature, keep dry and cool)
溶剤 & 溶解度
体外: 

DMSO : 100 mg/mL (288.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8833 mL 14.4163 mL 28.8326 mL
5 mM 0.5767 mL 2.8833 mL 5.7665 mL
10 mM 0.2883 mL 1.4416 mL 2.8833 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

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純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8833 mL 14.4163 mL 28.8326 mL 72.0814 mL
5 mM 0.5767 mL 2.8833 mL 5.7665 mL 14.4163 mL
10 mM 0.2883 mL 1.4416 mL 2.8833 mL 7.2081 mL
15 mM 0.1922 mL 0.9611 mL 1.9222 mL 4.8054 mL
20 mM 0.1442 mL 0.7208 mL 1.4416 mL 3.6041 mL
25 mM 0.1153 mL 0.5767 mL 1.1533 mL 2.8833 mL
30 mM 0.0961 mL 0.4805 mL 0.9611 mL 2.4027 mL
40 mM 0.0721 mL 0.3604 mL 0.7208 mL 1.8020 mL
50 mM 0.0577 mL 0.2883 mL 0.5767 mL 1.4416 mL
60 mM 0.0481 mL 0.2403 mL 0.4805 mL 1.2014 mL
80 mM 0.0360 mL 0.1802 mL 0.3604 mL 0.9010 mL
100 mM 0.0288 mL 0.1442 mL 0.2883 mL 0.7208 mL
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Desmethylcitalopram hydrochloride Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Desmethylcitalopram97743-99-2DCITCytochrome P450CYPsCitalopramantidepressant2D62C19Inhibitorinhibitorinhibit

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製品名:
Desmethylcitalopram hydrochloride
製品番号:
HY-113739
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