2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. Enpp-1-IN-2

Enpp-1-IN-2 (Compound C) is a potent ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1) inhibitor with IC50 values of 0.26, 0.48 and 2.0 μM evaluated by means of TG-mAMP, pNP-TMP, and ATP assays, respectively. TG (Tokyo Green)-mAMP: a newly synthesized sensitive ENPP1 fluorescence probe.

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Enpp-1-IN-2

Enpp-1-IN-2 화학구조

CAS No. : 2378640-92-5

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
1 mg 해외재고보유
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

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Enpp-1-IN-2 Related Antibodies

Top Publications Citing Use of Products

View All Phosphodiesterase (PDE) Isoform Specific Products:

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PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

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  • 순도&문서

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제품 설명

Enpp-1-IN-2 (Compound C) is a potent ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1) inhibitor with IC50 values of 0.26, 0.48 and 2.0 μM evaluated by means of TG-mAMP, pNP-TMP, and ATP assays, respectively. TG (Tokyo Green)-mAMP: a newly synthesized sensitive ENPP1 fluorescence probe[1].

IC50 & Target

IC50: 0.26 μM (TG-mAMP assay), 0.48 μM (pNP-TMP assay), 2.0 μM (ATP assay)[1]
분자량

282.34

화학식

C15H18N6
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC1=NC2=NC=NN2C(N(C)C)=C1CC3=CC=CC(N)=C3
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

DMSO : 100 mg/mL (354.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5418 mL 17.7091 mL 35.4183 mL
5 mM 0.7084 mL 3.5418 mL 7.0837 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5418 mL 17.7091 mL 35.4183 mL 88.5457 mL
5 mM 0.7084 mL 3.5418 mL 7.0837 mL 17.7091 mL
10 mM 0.3542 mL 1.7709 mL 3.5418 mL 8.8546 mL
15 mM 0.2361 mL 1.1806 mL 2.3612 mL 5.9030 mL
20 mM 0.1771 mL 0.8855 mL 1.7709 mL 4.4273 mL
25 mM 0.1417 mL 0.7084 mL 1.4167 mL 3.5418 mL
30 mM 0.1181 mL 0.5903 mL 1.1806 mL 2.9515 mL
40 mM 0.0885 mL 0.4427 mL 0.8855 mL 2.2136 mL
50 mM 0.0708 mL 0.3542 mL 0.7084 mL 1.7709 mL
60 mM 0.0590 mL 0.2952 mL 0.5903 mL 1.4758 mL
80 mM 0.0443 mL 0.2214 mL 0.4427 mL 1.1068 mL
100 mM 0.0354 mL 0.1771 mL 0.3542 mL 0.8855 mL
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Enpp-1-IN-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Enpp-1-IN-22378640-92-5Phosphodiesterase (PDE)malignant breast cancerInhibitorinhibitorinhibit

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상품명:
Enpp-1-IN-2
Cat. No.:
HY-139362
수량:
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