1. Protein Tyrosine Kinase/RTK
  2. FGFR
  3. FGFR1/DDR2 inhibitor 1

FGFR1/DDR2 inhibitor 1 

Cat. No.: HY-114311
Handling Instructions

FGFR1/DDR2 inhibitor 1 (compound 11k) is an inhibitor of fibroblast growth factor receptor 1 (FGFR1) and discoindin domain receptor 2 (DDR2), with IC50 values of 31.1 nM, 108.4 nM and 3.2 nM for FGFR1, KG-1, and DDR2, respectively.

For research use only. We do not sell to patients.

FGFR1/DDR2 inhibitor 1 Chemical Structure

FGFR1/DDR2 inhibitor 1 Chemical Structure

CAS No. : 2308497-58-5

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Description

FGFR1/DDR2 inhibitor 1 (compound 11k) is an inhibitor of fibroblast growth factor receptor 1 (FGFR1) and discoindin domain receptor 2 (DDR2), with IC50 values of 31.1 nM, 108.4 nM and 3.2 nM for FGFR1, KG-1, and DDR2, respectively[1].

IC50 & Target

IC50: 31.1 nM (FGFR1), 108.4 nM (KG-1), 3.2 nM (DDR2)[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

501.50

Formula

C₂₈H₂₂F₃N₅O

CAS No.

2308497-58-5

SMILES

O=C(NC1=CC=CC(C(F)(F)F)=C1)C2=CC=C(C)C(C3=CC4=C(C=C3)C(C5=CN(C6CC6)N=C5)=NN4)=C2

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Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
FGFR1/DDR2 inhibitor 1
Cat. No.:
HY-114311
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FGFR1/DDR2 inhibitor 1

Cat. No.: HY-114311