2308497-58-5
2308497-58-5
Chemical Structure
FGFR1/DDR2 inhibitor 1
- CAS No.: 2308497-58-5
- Formula:C28H22F3N5O
- Molecular Weight:501.50
IUPAC Name: 3-(3-(1-cyclopropyl-1H-pyrazol-4-yl)-1H-indazol-6-yl)-4-methyl-N-(3-(trifluoromethyl)phenyl)benzamide
InChIKey: ZEOWTGPWHLSLOG-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=CC(C(F)(F)F)=C1)C2=CC=C(C)C(C3=CC4=C(C=C3)C(C5=CN(C6CC6)N=C5)=NN4)=C2
Biological Activity: FGFR1/DDR2 inhibitor 1 is an orally active inhibitor of fibroblast growth factor receptor 1 (FGFR1) and discoindin domain receptor 2 (DDR2), with IC50 values of 31.1 nM and 3.2 nM, respectively. Antitumor activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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FGFR1/DDR2 inhibitor 1 | 98.26% | FGFR1/DDR2 inhibitor 1 is an orally active inhibitor of fibroblast growth factor receptor 1 (FGFR1) and discoindin domain receptor 2 (DDR2), with IC50 values of 31.1 nM and 3.2 nM, respectively. Antitumor activity. | ||||||||||||||||||||
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References
Keywords
