2. 天然物
  3. Disease Research Fields Plants Terpenoids
  4. Araliaceae Cucurbitaceae Cancer Triterpenes
  5. Panax ginseng C. A. Meyer Gynostemma pentaphyllum (Thunb.) Makino
  6. Gypenoside LXXV

Gypenoside LXXV, isolated from Gynostemma pentaphyllum, is one of the deglycosylated shapes of ginsenoside Rb1. Gypenoside LXXV significantly reduces cancer cell viability and displays an anti-cancer effect.

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Gypenoside LXXV

Gypenoside LXXV 構造式

CAS 番号 : 110261-98-8

容量 価格（税別） 在庫状況 数量
1 mg $140 在庫あり
5 mg $350 在庫あり
10 mg   お問い合わせ  
50 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Based on 1 publication(s) in Google Scholar

Gypenoside LXXV 関連抗体

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  • 純度とドキュメンテーション

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製品説明

Gypenoside LXXV, isolated from Gynostemma pentaphyllum, is one of the deglycosylated shapes of ginsenoside Rb1. Gypenoside LXXV significantly reduces cancer cell viability and displays an anti-cancer effect[1].

体外実験

Gypenoside LXXV (1.0-100 μM; for 48 hours) reduces proliferation in a dose-dependent manner[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Gypenoside LXXV 関連抗体

Cell Viability Assay[1]

Cell Line: Three cancer cell lines (HeLa (cervical cancer cell line), B16 (melanoma cell line), and MDA-MB231 (human breast cancer cell line)
Concentration: 1.0-100 μM
Incubation Time: For 48 hours
Result: Reduced proliferation in a dose-dependent manner and inhibited almost all cancer cells at 50 μM.
分子量

785.01

分子式

C42H72O13
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]([C@@]([C@@]1([H])[C@@]2([H])[C@@](CC/C=C(C)/C)(C)O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]([C@H]3O)CO[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O)CO)(CC2)C)(CC[C@@]5([H])C6(C)C)[C@@](C[C@H]1O)([H])[C@]5(CC[C@@H]6O)C
Structure Classification
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
体外: 

DMSO : 100 mg/mL (127.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2739 mL 6.3693 mL 12.7387 mL
5 mM 0.2548 mL 1.2739 mL 2.5477 mL
10 mM 0.1274 mL 0.6369 mL 1.2739 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 98.83%

COA (264 KB) HNMR (195 KB) CNMR (209 KB) RP-HPLC (181 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.2739 mL 6.3693 mL 12.7387 mL 31.8467 mL
5 mM 0.2548 mL 1.2739 mL 2.5477 mL 6.3693 mL
10 mM 0.1274 mL 0.6369 mL 1.2739 mL 3.1847 mL
15 mM 0.0849 mL 0.4246 mL 0.8492 mL 2.1231 mL
20 mM 0.0637 mL 0.3185 mL 0.6369 mL 1.5923 mL
25 mM 0.0510 mL 0.2548 mL 0.5095 mL 1.2739 mL
30 mM 0.0425 mL 0.2123 mL 0.4246 mL 1.0616 mL
40 mM 0.0318 mL 0.1592 mL 0.3185 mL 0.7962 mL
50 mM 0.0255 mL 0.1274 mL 0.2548 mL 0.6369 mL
60 mM 0.0212 mL 0.1062 mL 0.2123 mL 0.5308 mL
80 mM 0.0159 mL 0.0796 mL 0.1592 mL 0.3981 mL
100 mM 0.0127 mL 0.0637 mL 0.1274 mL 0.3185 mL
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Gypenoside LXXV Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gypenoside LXXV110261-98-8OthersginsenosideRb1HeLacervicalcancerB16melanomaMDA-MB231breastInhibitorinhibitorinhibit

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製品名:
Gypenoside LXXV
製品番号:
HY-N7678
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