Isobutyryl-L-carnitine chloride

Name: Isobutyryl-L-carnitine chloride
Brand: MedChemExpress
SKU: HY-113165A
Rating: 4.5 (1 reviews)

Cat. No.: HY-113165A Pureza: 98.0%: Ficha de datos
COA

SDS
Instrucciones de manejo
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Technical Support

Isobutyryl-L-carnitine chloride is a product of the acyl-CoA dehydrogenases.

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Isobutyryl-L-carnitine chloride Estructura química

No. CAS : 6920-31-6

Tamaño	Stock	Cantidad

Muestra gratis (0.1 - 0.2 mg)	Solicite ahora
Muestra gratis (0.1 - 0.2 mg)	Solicite ahora
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	En stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	En stock	Estimated Time of Arrival: December 31
Solid
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
100 mg	En stock	Estimated Time of Arrival: December 31
200 mg	Obtener un presupuesto
500 mg	Obtener un presupuesto

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This product is a controlled substance and not for sale in your territory.

Revisión del cliente

Based on 1 publication(s) in Google Scholar

Other Forms of Isobutyryl-L-carnitine chloride:

Isobutyryl-L-carnitine-d₃ chloride In-stock
Isobutyryl-L-carnitine In-stock
Isobutyryl-L-carnitine chloride-d₆ Obtener un presupuesto
Isobutyryl-L-carnitine chloride (Standard) Obtener un presupuesto

1 Publications Citing Use of MCE Isobutyryl-L-carnitine chloride

•Microchem J. 2025 Aug 28;217:115058.

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Ver todos los productos específicos de isoformas Endogenous Metabolite:

Ver todas las isoformas

Human Endogenous Metabolite Microbial Metabolite

Actividad biológica
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Referencias
Revisión del cliente

Descripciòn

Isobutyryl-L-carnitine chloride is a product of the acyl-CoA dehydrogenases^[1].

IC₅₀ & Target

Human Endogenous Metabolite

Peso molecular

267.75

Fòrmula

C₁₁H₂₂ClNO₄

No. CAS

6920-31-6

Appearance

Solid

Color

White to off-white

SMILES

O=C(C(C)C)O[C@H](CC(O)=O)C[N+](C)(C)C.[Cl-]

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Endogenous metabolite

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad

In Vitro:

H₂O : 250 mg/mL (933.71 mM; Need ultrasonic)

DMSO : 30 mg/mL (112.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.7348 mL	18.6741 mL	37.3483 mL
5 mM	0.7470 mL	3.7348 mL	7.4697 mL
10 mM	0.3735 mL	1.8674 mL	3.7348 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.08 mg/mL (7.77 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.08 mg/mL (7.77 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.08 mg/mL (7.77 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL Corn oil, and mix evenly.

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 100 mg/mL (373.48 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Pureza y Documentación

Purity: 98.0%

Select Batch:

Ficha de datos (273 KB) SDS (393 KB)

COA (251 KB) HNMR (240 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Cao C, et, al. Metabonomic analysis of toxic action of long-term low-level exposure to acrylamide in rat serum. Hum Exp Toxicol. 2018 Dec; 37(12): 1282-1292. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	3.7348 mL	18.6741 mL	37.3483 mL	93.3707 mL
	5 mM	0.7470 mL	3.7348 mL	7.4697 mL	18.6741 mL
	10 mM	0.3735 mL	1.8674 mL	3.7348 mL	9.3371 mL
	15 mM	0.2490 mL	1.2449 mL	2.4899 mL	6.2247 mL
	20 mM	0.1867 mL	0.9337 mL	1.8674 mL	4.6685 mL
	25 mM	0.1494 mL	0.7470 mL	1.4939 mL	3.7348 mL
	30 mM	0.1245 mL	0.6225 mL	1.2449 mL	3.1124 mL
	40 mM	0.0934 mL	0.4669 mL	0.9337 mL	2.3343 mL
	50 mM	0.0747 mL	0.3735 mL	0.7470 mL	1.8674 mL
	60 mM	0.0622 mL	0.3112 mL	0.6225 mL	1.5562 mL
	80 mM	0.0467 mL	0.2334 mL	0.4669 mL	1.1671 mL
	100 mM	0.0373 mL	0.1867 mL	0.3735 mL	0.9337 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.