Isobutyryl-L-carnitine-d3 chloride
Based on 1 Customer Validation
Isobutyryl-L-carnitine-d3 chloride is the d3-labeled Isobutyryl-L-carnitine chloride (HY-113165A). Isobutyryl-L-carnitine chloride is a biomarker. Isobutyryl-L-carnitine chloride is a product of acyl-CoA dehydrogenases involved in fatty acid β-oxidation, and it buffers the mitochondrial acyl-CoA/CoA ratio, oxidizes branched-chain amino acids, and supports the endogenous antioxidant defense system. Isobutyryl-L-carnitine chloride is a plasma biomarker of hepatic OCT1 transporter inhibition. Isobutyryl-L-carnitine chloride is a urinary biomarker of renal cell carcinoma, and its levels are elevated one year after nephrectomy compared with before nephrectomy. Isobutyryl-L-carnitine chloride can be used in research on renal cell carcinoma.
For research use only. We do not sell to patients.
- Purity : 99%
- Formula: C11H19D3ClNO4
- Molecular Weight:270.77
-
Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Endogenous Metabolite Isoforms
More
Biological Activity
Description
IC50 & Target
|
Human Endogenous Metabolite |
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
Unlabeled CAS 6920-31-6
-
Appearance Solid
-
Molecular Weight 270.77
-
Formula C11H19D3ClNO4
-
Color White to off-white
-
SMILES
[2H]C([N+](C[C@@H](CC(O)=O)OC(C(C)C)=O)(C)C)([2H])[2H].[Cl-]
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
-
Data Sheet (272 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Isobutyryl-L-carnitine-d3
- Isotope-Labeled Compounds
- Endogenous Metabolite
- hepatic organic cation transporter OCT1
- HILIC-MS/HRMS assay
- SLC22A1
- Wistar rat serum
- clear cell and papillary RCC
- peroxisomal dysfunction
- acyl-CoA dehydrogenases
- fatty acid beta-oxidation
- acrylamide exposure
- renal cell carcinoma
- Inhibitor
- inhibitor
- inhibit