Papain inhibitor (Synonyms: Glycylglycyl-L-tyrosyl-L-arginine)

Cat. No.: HY-P1315 Purity: 99.80%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Papain inhibitor (Glycylglycyl-L-tyrosyl-L-arginine) is a competitive papain-targeting enzyme inhibitor with a K_i of 9 μM. Papain inhibitor binds directly to the substrate binding site of papain, inhibiting substrate hydrolysis by the enzyme. Papain inhibitor functions as a component of an electrochemical probe for the detection of papain.

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Papain inhibitor 화학구조

CAS No. : 70195-20-9

사이즈	재고	수량
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	해외재고보유	Estimated Time of Arrival: December 31
200 mg	견적 받기
500 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

IC₅₀ & Target

Papain^[1].

In Vitro

Papain inhibitor (Compound 7) acts as a competitive inhibitor of purified papain with an inhibition constant of 9 μM at pH 6.2^[1].
Papain inhibitor binds to purified papain at pH 6.2, inducing a 30 mV cathodic shift in its ferrocene/ferrocenium redox potential^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

451.48

화학식

C₁₉H₂₉N₇O₆

CAS No.

70195-20-9

Appearance

Solid

Color

White to off-white

Sequence

Gly-Gly-Tyr-Arg

Sequence Shortening

GGYR

선적

Room temperature in continental US; may vary elsewhere.

보관

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도

In Vitro:

DMSO : 50 mg/mL (110.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2149 mL	11.0747 mL	22.1494 mL
5 mM	0.4430 mL	2.2149 mL	4.4299 mL
10 mM	0.2215 mL	1.1075 mL	2.2149 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.80%

Select Batch:

Data Sheet (270 KB) SDS (396 KB)

COA (246 KB) RP-HPLC (263 KB) MS (68 KB) Elemental Analysis Report (105 KB)

Handling Instructions (2659 KB)

References

[1]. Plumb K, et al. Interaction of a ferrocenoyl-modified peptide with papain: toward protein-sensitive electrochemical probes. Bioconjug Chem. 2003;14(3):601-606. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.2149 mL	11.0747 mL	22.1494 mL	55.3734 mL
	5 mM	0.4430 mL	2.2149 mL	4.4299 mL	11.0747 mL
	10 mM	0.2215 mL	1.1075 mL	2.2149 mL	5.5373 mL
	15 mM	0.1477 mL	0.7383 mL	1.4766 mL	3.6916 mL
	20 mM	0.1107 mL	0.5537 mL	1.1075 mL	2.7687 mL
	25 mM	0.0886 mL	0.4430 mL	0.8860 mL	2.2149 mL
	30 mM	0.0738 mL	0.3692 mL	0.7383 mL	1.8458 mL
	40 mM	0.0554 mL	0.2769 mL	0.5537 mL	1.3843 mL
	50 mM	0.0443 mL	0.2215 mL	0.4430 mL	1.1075 mL
	60 mM	0.0369 mL	0.1846 mL	0.3692 mL	0.9229 mL
	80 mM	0.0277 mL	0.1384 mL	0.2769 mL	0.6922 mL
	100 mM	0.0221 mL	0.1107 mL	0.2215 mL	0.5537 mL

Papain inhibitor Related Classifications

Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Papain inhibitor70195-20-9Glycylglycyl-L-tyrosyl-L-arginineCathepsinelectrochemical propertiessubstrate binding siteelectrochemical probesubstrate hydrolysiscyclic voltammetryferrocene/ferrocenium redox couplepapainInhibitorinhibitorinhibit

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Papain inhibitor (Synonyms: Glycylglycyl-L-tyrosyl-L-arginine)

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