1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Phosphoenolpyruvic acid

Phosphoenolpyruvic acid  (Synonyms: Phosphoenolpyruvate)

Cat. No.: HY-113049
Handling Instructions Technical Support

Phosphoenolpyruvic acid (Phosphoenolpyruvate) is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid also exhibits cytoprotective and anti-oxidative properties.

It is advisable to consider the salt form (Phosphoenolpyruvic acid potassium) that retains the same biological activity.

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Phosphoenolpyruvic acid

Phosphoenolpyruvic acid 화학구조

CAS No. : 138-08-9

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1 Publications Citing Use of MCE Phosphoenolpyruvic acid

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제품 설명

Phosphoenolpyruvic acid (Phosphoenolpyruvate) is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid also exhibits cytoprotective and anti-oxidative properties[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Phosphoenolpyruvic acid (0.1-10 mM) significantly attenuates the decrease in cell viability induced by hydrogen peroxide (H2O2) in HeLa cells in a dose-dependent manner. The H2O2-stimulated increase in intracellular reactive oxygen species is significantly reduced by Phosphoenolpyruvic acid[1].
Phosphoenolpyruvic acid demonstrates scavenging potential against hydroxyl radicals[1].
Phosphoenolpyruvic acid (10 mM) slightly inhibits the decrease in cellular ATP content induced by H2O2, but does not show any effects at low doses (0.1 mM and 1 mM)[1].
Phosphoenolpyruvic acid (0.1-10 mM) also attenuates the cell injury but not the decrease in intracellular ATP content, induced by 2-Deoxy-D-glucose (HY-13966), a glycolysis inhibitor[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

168.04

화학식

C3H5O6P

CAS No.
SMILES

C=C(OP(O)(O)=O)C(O)=O

Initial Source
선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
Phosphoenolpyruvic acid
Cat. No.:
HY-113049
수량:
MCE Japan Authorized Agent: