Phosphoenolpyruvic acid trisodium
Based on 2 publication(s) in Google Scholar
Phosphoenolpyruvic acid (Phosphoenolpyruvate) trisodium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid trisodium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid trisodium also exhibits cytoprotective and anti-oxidative properties.
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- CAS No.: 5541-93-5
- Formula: C3H2Na3O6P
- Molecular Weight:233.99
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Publications Citing Use of MedChemExpress (MCE) Phosphoenolpyruvic acid trisodium
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Biological Activity
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Human Endogenous Metabolite |
Phosphoenolpyruvic acid (0.1-10 mM) trisodium significantly attenuates the decrease in cell viability induced by hydrogen peroxide (H2O2) in HeLa cells in a dose-dependent manner. The H2O2-stimulated increase in intracellular reactive oxygen species is significantly reduced by Phosphoenolpyruvic acid trisodium[1].
Phosphoenolpyruvic acid trisodium demonstrates scavenging potential against hydroxyl radicals[1].
Phosphoenolpyruvic acid (10 mM) trisodium slightly inhibits the decrease in cellular ATP content induced by H2O2, but does not show any effects at low doses (0.1 mM and 1 mM)[1].
Phosphoenolpyruvic acid (0.1-10 mM) trisodium also attenuates the cell injury but not the decrease in intracellular ATP content, induced by 2-Deoxy-D-glucose (HY-13966), a glycolysis inhibitor[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 5541-93-5
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Molecular Weight 233.99
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Formula C3H2Na3O6P
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SMILES
C=C(OP(O[Na])(O[Na])=O)C(O[Na])=O
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Synonyms
Phosphoenolpyruvate trisodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Cell Host Microbe
Microbiota-driven gut-brain signaling underlies antidepressant effects of a GLP-1 analog. [Abstract]2026 Jun 10;34(6):1000-1017.e5. PMID: 42269582 -
Eur J Immunol
Glycolytic metabolite phosphoenolpyruvate protects host from viral infection through promoting AATK expression. [Abstract]2023 Dec;53(12):e2350536. PMID: 37724936
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Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Phosphoenolpyruvic acid trisodium Related Classifications
HY-113049A Related Classifications
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