Phosphoenolpyruvic acid
Based on 2 publication(s) in Google Scholar
Phosphoenolpyruvic acid (Phosphoenolpyruvate) is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid also exhibits cytoprotective and anti-oxidative properties.
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- CAS No.: 138-08-9
- Formula: C3H5O6P
- Molecular Weight:168.04
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Publications Citing Use of MedChemExpress (MCE) Phosphoenolpyruvic acid
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Biological Activity
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Human Endogenous Metabolite |
Phosphoenolpyruvic acid (0.1-10 mM) significantly attenuates the decrease in cell viability induced by hydrogen peroxide (H2O2) in HeLa cells in a dose-dependent manner. The H2O2-stimulated increase in intracellular reactive oxygen species is significantly reduced by Phosphoenolpyruvic acid[1].
Phosphoenolpyruvic acid demonstrates scavenging potential against hydroxyl radicals[1].
Phosphoenolpyruvic acid (10 mM) slightly inhibits the decrease in cellular ATP content induced by H2O2, but does not show any effects at low doses (0.1 mM and 1 mM)[1].
Phosphoenolpyruvic acid (0.1-10 mM) also attenuates the cell injury but not the decrease in intracellular ATP content, induced by 2-Deoxy-D-glucose (HY-13966), a glycolysis inhibitor[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 138-08-9
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Molecular Weight 168.04
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Formula C3H5O6P
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SMILES
C=C(OP(O)(O)=O)C(O)=O
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Synonyms
Phosphoenolpyruvate
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Cell Host Microbe
Microbiota-driven gut-brain signaling underlies antidepressant effects of a GLP-1 analog. [Abstract]2026 Jun 10;34(6):1000-1017.e5. PMID: 42269582 -
Eur J Immunol
Glycolytic metabolite phosphoenolpyruvate protects host from viral infection through promoting AATK expression. [Abstract]2023 Dec;53(12):e2350536. PMID: 37724936
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Phosphoenolpyruvic acid Related Classifications
HY-113049 Related Classifications
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