2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Phosphoenolpyruvic acid

Phosphoenolpyruvic acid  (Synonyms: Phosphoenolpyruvate)

Cat. No.: HY-113049
Handling Instructions Technical Support

Phosphoenolpyruvic acid (Phosphoenolpyruvate) is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid also exhibits cytoprotective and anti-oxidative properties.

It is advisable to consider the salt form (Phosphoenolpyruvic acid potassium) that retains the same biological activity.

For research use only. We do not sell to patients.

Phosphoenolpyruvic acid

Phosphoenolpyruvic acid Chemical Structure

CAS No. : 138-08-9

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Other In-stock Forms of Phosphoenolpyruvic acid:

Phosphoenolpyruvic acid Related Antibodies

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1 Publications Citing Use of MCE Phosphoenolpyruvic acid

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Description

Phosphoenolpyruvic acid (Phosphoenolpyruvate) is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid also exhibits cytoprotective and anti-oxidative properties[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Phosphoenolpyruvic acid (0.1-10 mM) significantly attenuates the decrease in cell viability induced by hydrogen peroxide (H2O2) in HeLa cells in a dose-dependent manner. The H2O2-stimulated increase in intracellular reactive oxygen species is significantly reduced by Phosphoenolpyruvic acid[1].
Phosphoenolpyruvic acid demonstrates scavenging potential against hydroxyl radicals[1].
Phosphoenolpyruvic acid (10 mM) slightly inhibits the decrease in cellular ATP content induced by H2O2, but does not show any effects at low doses (0.1 mM and 1 mM)[1].
Phosphoenolpyruvic acid (0.1-10 mM) also attenuates the cell injury but not the decrease in intracellular ATP content, induced by 2-Deoxy-D-glucose (HY-13966), a glycolysis inhibitor[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Phosphoenolpyruvic acid Related Antibodies
Molecular Weight

168.04

Formula

C3H5O6P
CAS No.
SMILES

C=C(OP(O)(O)=O)C(O)=O
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Phosphoenolpyruvic acid Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phosphoenolpyruvic acid138-08-9PhosphoenolpyruvateEndogenous MetaboliteInhibitorinhibitorinhibit

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