Phosphoenolpyruvic acid potassium
Based on 2 publication(s) in Google Scholar
Phosphoenolpyruvic acid (Phosphoenolpyruvate) potassium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid potassium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid potassium also exhibits cytoprotective and anti-oxidative properties.
For research use only. We do not sell to patients.
- Purity: 99.86%
- CAS No.: 4265-07-0
- Formula: C3H4KO6P
- Molecular Weight:206.13
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-W008807R
Phosphoenolpyruvic acid potassium (Standard)
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HY-N7386A
D-Erythrose 4-phosphate sodium
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HY-P2806
Pyruvate Kinase, Microorganism
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HY-112537
D-Glucose 6-phosphate
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HY-W010918
Adenosine 5'-diphosphate
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HY-113596
Acetyl Coenzyme A trisodium
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HY-113407A
D-Fructose-6-phosphate disodium
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HY-128851
Coenzyme A
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HY-W015913
Pyruvic acid sodium
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HY-N1150
Thymidine
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HY-Y0337
L-Cysteine
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HY-N0323
Bilirubin
Publications Citing Use of MedChemExpress (MCE) Phosphoenolpyruvic acid potassium
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
Phosphoenolpyruvic acid (0.1-10 mM) potassium significantly attenuates the decrease in cell viability induced by hydrogen peroxide (H2O2) in HeLa cells in a dose-dependent manner. The H2O2-stimulated increase in intracellular reactive oxygen species is significantly reduced by Phosphoenolpyruvic acid potassium[1].
Phosphoenolpyruvic acid potassium demonstrates scavenging potential against hydroxyl radicals[1].
Phosphoenolpyruvic acid (10 mM) potassium slightly inhibits the decrease in cellular ATP content induced by H2O2, but does not show any effects at low doses (0.1 mM and 1 mM)[1].
Phosphoenolpyruvic acid (0.1-10 mM) potassium also attenuates the cell injury but not the decrease in intracellular ATP content, induced by 2-Deoxy-D-glucose (HY-13966), a glycolysis inhibitor[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 4265-07-0
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Appearance Solid
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Molecular Weight 206.13
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Formula C3H4KO6P
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Color White to off-white
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SMILES
O=C(C(OP(O)(O[K])=O)=C)O
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Synonyms
Phosphoenolpyruvate potassium
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (2)
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Journal Impact Factor
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Most Recent
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Cell Host Microbe
Microbiota-driven gut-brain signaling underlies antidepressant effects of a GLP-1 analog. [Abstract]2026 Jun 10;34(6):1000-1017.e5. PMID: 42269582 -
Eur J Immunol
Glycolytic metabolite phosphoenolpyruvate protects host from viral infection through promoting AATK expression. [Abstract]2023 Dec;53(12):e2350536. PMID: 37724936
Solvent & Solubility
H2O : 116.67 mg/mL (566.00 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (485.13 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.8513 mL | 24.2565 mL | 48.5131 mL | 121.2827 mL |
| 5 mM | 0.9703 mL | 4.8513 mL | 9.7026 mL | 24.2565 mL | |
| 10 mM | 0.4851 mL | 2.4257 mL | 4.8513 mL | 12.1283 mL | |
| 15 mM | 0.3234 mL | 1.6171 mL | 3.2342 mL | 8.0855 mL | |
| 20 mM | 0.2426 mL | 1.2128 mL | 2.4257 mL | 6.0641 mL | |
| 25 mM | 0.1941 mL | 0.9703 mL | 1.9405 mL | 4.8513 mL | |
| 30 mM | 0.1617 mL | 0.8086 mL | 1.6171 mL | 4.0428 mL | |
| 40 mM | 0.1213 mL | 0.6064 mL | 1.2128 mL | 3.0321 mL | |
| 50 mM | 0.0970 mL | 0.4851 mL | 0.9703 mL | 2.4257 mL | |
| 60 mM | 0.0809 mL | 0.4043 mL | 0.8086 mL | 2.0214 mL | |
| 80 mM | 0.0606 mL | 0.3032 mL | 0.6064 mL | 1.5160 mL | |
| 100 mM | 0.0485 mL | 0.2426 mL | 0.4851 mL | 1.2128 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Phosphoenolpyruvic acid potassium Related Classifications
HY-W008807 Related Classifications
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