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  3. Coenzyme A

Coenzyme A 

Cat. No.: HY-128851 Purity: 91.47%
COA Handling Instructions

Coenzyme A, a ubiquitous essential cofactor, is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the metabolism of carboxylic acids, including short- and long-chain fatty acids.

For research use only. We do not sell to patients.

Coenzyme A Chemical Structure

Coenzyme A Chemical Structure

CAS No. : 85-61-0

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Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 51 In-stock
Solution
10 mM * 1 mL in DMSO USD 51 In-stock
Solid
5 mg USD 50 In-stock
10 mg USD 60 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Coenzyme A:

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Description

Coenzyme A, a ubiquitous essential cofactor, is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the metabolism of carboxylic acids, including short- and long-chain fatty acids[1].

Clinical Trial
Molecular Weight

767.53

Appearance

Solid

Formula

C21H36N7O16P3S

CAS No.
SMILES

CC([C@H](C(NCCC(NCCS)=O)=O)O)(C)COP(OP(OC[C@H]1O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@H](O)[C@@H]1OP(O)(O)=O)(O)=O)(O)=O

Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (162.86 mM; Need ultrasonic)

DMSO : 100 mg/mL (130.29 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3029 mL 6.5144 mL 13.0288 mL
5 mM 0.2606 mL 1.3029 mL 2.6058 mL
10 mM 0.1303 mL 0.6514 mL 1.3029 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 25 mg/mL (32.57 mM); Clear solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 1.63 mg/mL (2.12 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 1.63 mg/mL (2.12 mM); Clear solution

  • 4.

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 1.63 mg/mL (2.12 mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation

Purity: ≥97.0%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Coenzyme A
Cat. No.:
HY-128851
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