Phosphoenolpyruvic acid cyclohexylammonium salt
Based on 2 publication(s) in Google Scholar
Phosphoenolpyruvic acid (Phosphoenolpyruvate) cyclohexylammonium salt is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid cyclohexylammonium salt is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid cyclohexylammonium salt also exhibits cytoprotective and anti-oxidative properties.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 10526-80-4
- Formula: C9H18NO6P
- Molecular Weight:267.22
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) Phosphoenolpyruvic acid cyclohexylammonium salt
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Description
In Vitro
Phosphoenolpyruvic acid (0.1-10 mM) cyclohexylammonium salt significantly attenuates the decrease in cell viability induced by hydrogen peroxide (H2O2) in HeLa cells in a dose-dependent manner. The H2O2-stimulated increase in intracellular reactive oxygen species is significantly reduced by Phosphoenolpyruvic acid cyclohexylammonium salt[1].
Phosphoenolpyruvic acid cyclohexylammonium salt demonstrates scavenging potential against hydroxyl radicals[1].
Phosphoenolpyruvic acid (10 mM) cyclohexylammonium salt slightly inhibits the decrease in cellular ATP content induced by H2O2, but does not show any effects at low doses (0.1 mM and 1 mM)[1].
Phosphoenolpyruvic acid (0.1-10 mM) cyclohexylammonium salt also attenuates the cell injury but not the decrease in intracellular ATP content, induced by 2-Deoxy-D-glucose (HY-13966), a glycolysis inhibitor[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 10526-80-4
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Appearance Solid
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Molecular Weight 267.22
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Formula C9H18NO6P
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Color White to yellow
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SMILES
NC1CCCCC1.C=C(OP(O)(O)=O)C(O)=O
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Synonyms
Phosphoenolpyruvate cyclohexylammonium salt
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (2)
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Journal Impact Factor
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Most Recent
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Cell Host Microbe
Microbiota-driven gut-brain signaling underlies antidepressant effects of a GLP-1 analog. [Abstract]2026 Jun 10;34(6):1000-1017.e5. PMID: 42269582 -
Eur J Immunol
Glycolytic metabolite phosphoenolpyruvate protects host from viral infection through promoting AATK expression. [Abstract]2023 Dec;53(12):e2350536. PMID: 37724936
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (374.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7422 mL | 18.7112 mL | 37.4223 mL | 93.5559 mL |
| 5 mM | 0.7484 mL | 3.7422 mL | 7.4845 mL | 18.7112 mL | |
| 10 mM | 0.3742 mL | 1.8711 mL | 3.7422 mL | 9.3556 mL | |
| 15 mM | 0.2495 mL | 1.2474 mL | 2.4948 mL | 6.2371 mL | |
| 20 mM | 0.1871 mL | 0.9356 mL | 1.8711 mL | 4.6778 mL | |
| 25 mM | 0.1497 mL | 0.7484 mL | 1.4969 mL | 3.7422 mL | |
| 30 mM | 0.1247 mL | 0.6237 mL | 1.2474 mL | 3.1185 mL | |
| 40 mM | 0.0936 mL | 0.4678 mL | 0.9356 mL | 2.3389 mL | |
| 50 mM | 0.0748 mL | 0.3742 mL | 0.7484 mL | 1.8711 mL | |
| 60 mM | 0.0624 mL | 0.3119 mL | 0.6237 mL | 1.5593 mL | |
| 80 mM | 0.0468 mL | 0.2339 mL | 0.4678 mL | 1.1694 mL | |
| 100 mM | 0.0374 mL | 0.1871 mL | 0.3742 mL | 0.9356 mL |