Phosphoenolpyruvic acid monosodium
Based on 2 publication(s) in Google Scholar
Phosphoenolpyruvic acid (Phosphoenolpyruvate) monosodium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid monosodium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid monosodium also exhibits cytoprotective and anti-oxidative properties.
For research use only. We do not sell to patients.
- Purity: 99.61%
- CAS No.: 53823-68-0
- Formula: C3H4NaO6P
- Molecular Weight:190.02
-
Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Phosphoenolpyruvic acid monosodium
MoreAll Endogenous Metabolite Isoforms
More
Biological Activity
Phosphoenolpyruvic acid (0.1-10 mM) monosodium significantly attenuates the decrease in cell viability induced by hydrogen peroxide (H2O2) in HeLa cells in a dose-dependent manner. The H2O2-stimulated increase in intracellular reactive oxygen species is significantly reduced by Phosphoenolpyruvic acid monosodium[1].
Phosphoenolpyruvic acid monosodium demonstrates scavenging potential against hydroxyl radicals[1].
Phosphoenolpyruvic acid (10 mM) monosodium slightly inhibits the decrease in cellular ATP content induced by H2O2, but does not show any effects at low doses (0.1 mM and 1 mM)[1].
Phosphoenolpyruvic acid (0.1-10 mM) monosodium also attenuates the cell injury but not the decrease in intracellular ATP content, induced by 2-Deoxy-D-glucose (HY-13966), a glycolysis inhibitor[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 53823-68-0
-
Appearance Solid
-
Molecular Weight 190.02
-
Formula C3H4NaO6P
-
Color White to off-white
-
SMILES
O=C(C(OP(O)(O[Na])=O)=C)O
-
Synonyms
Phosphoenolpyruvate monosodium
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
-
Journal Impact Factor
-
Most Recent
-
Cell Host Microbe
Microbiota-driven gut-brain signaling underlies antidepressant effects of a GLP-1 analog. [Abstract]2026 Jun 10;34(6):1000-1017.e5. PMID: 42269582 -
Eur J Immunol
Glycolytic metabolite phosphoenolpyruvate protects host from viral infection through promoting AATK expression. [Abstract]2023 Dec;53(12):e2350536. PMID: 37724936
Solvent & Solubility
H2O : ≥ 100 mg/mL (526.26 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (272 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.2626 mL | 26.3130 mL | 52.6260 mL | 131.5651 mL |
| 5 mM | 1.0525 mL | 5.2626 mL | 10.5252 mL | 26.3130 mL | |
| 10 mM | 0.5263 mL | 2.6313 mL | 5.2626 mL | 13.1565 mL | |
| 15 mM | 0.3508 mL | 1.7542 mL | 3.5084 mL | 8.7710 mL | |
| 20 mM | 0.2631 mL | 1.3157 mL | 2.6313 mL | 6.5783 mL | |
| 25 mM | 0.2105 mL | 1.0525 mL | 2.1050 mL | 5.2626 mL | |
| 30 mM | 0.1754 mL | 0.8771 mL | 1.7542 mL | 4.3855 mL | |
| 40 mM | 0.1316 mL | 0.6578 mL | 1.3157 mL | 3.2891 mL | |
| 50 mM | 0.1053 mL | 0.5263 mL | 1.0525 mL | 2.6313 mL | |
| 60 mM | 0.0877 mL | 0.4386 mL | 0.8771 mL | 2.1928 mL | |
| 80 mM | 0.0658 mL | 0.3289 mL | 0.6578 mL | 1.6446 mL | |
| 100 mM | 0.0526 mL | 0.2631 mL | 0.5263 mL | 1.3157 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Phosphoenolpyruvic acid monosodium Related Classifications
HY-W555010 Related Classifications
Powered by Bioz