2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Phosphoenolpyruvic acid

Phosphoenolpyruvic acid (Phosphoenolpyruvate) is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid also exhibits cytoprotective and anti-oxidative properties.

It is advisable to consider the salt form (Phosphoenolpyruvic acid potassium) that retains the same biological activity.

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Phosphoenolpyruvic acid

Phosphoenolpyruvic acid Chemical Structure

CAS No. : 138-08-9

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Phosphoenolpyruvic acid Related Antibodies

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Description

Phosphoenolpyruvic acid (Phosphoenolpyruvate) is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid also exhibits cytoprotective and anti-oxidative properties[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Phosphoenolpyruvic acid (0.1-10 mM) significantly attenuates the decrease in cell viability induced by hydrogen peroxide (H2O2) in HeLa cells in a dose-dependent manner. The H2O2-stimulated increase in intracellular reactive oxygen species is significantly reduced by Phosphoenolpyruvic acid[1].
Phosphoenolpyruvic acid demonstrates scavenging potential against hydroxyl radicals[1].
Phosphoenolpyruvic acid (10 mM) slightly inhibits the decrease in cellular ATP content induced by H2O2, but does not show any effects at low doses (0.1 mM and 1 mM)[1].
Phosphoenolpyruvic acid (0.1-10 mM) also attenuates the cell injury but not the decrease in intracellular ATP content, induced by 2-Deoxy-D-glucose (HY-13966), a glycolysis inhibitor[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Phosphoenolpyruvic acid Related Antibodies
Masse moléculaire

168.04

Formule

C3H5O6P
CAS No.
SMILES

C=C(OP(O)(O)=O)C(O)=O
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Phosphoenolpyruvic acid Related Classifications

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Keywords:

Phosphoenolpyruvic acid138-08-9PhosphoenolpyruvateEndogenous MetaboliteInhibitorinhibitorinhibit

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