2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. Picoplatin

Picoplatin (AMD473) is a platinum-based antineoplastic agent. Picoplatin is specifically to circumvent thiol-mediated drug resistance by sterically hindering its reaction with glutathione (GSH) while still retaining the ability to form cytotoxic lesions with DNA.

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Picoplatin

Picoplatin Estructura química

No. CAS : 181630-15-9

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Picoplatin Related Antibodies

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Descripciòn

Picoplatin (AMD473) is a platinum-based antineoplastic agent. Picoplatin is specifically to circumvent thiol-mediated drug resistance by sterically hindering its reaction with glutathione (GSH) while still retaining the ability to form cytotoxic lesions with DNA[1].

Ensayo clínico
Peso molecular

376.15

Fòrmula

C6H10Cl2N2Pt
No. CAS
Appearance

Solid

Color

Light yellow to yellow

SMILES

[Cl-][Pt+2]([N]1=C(C)C=CC=C1)([NH3])[Cl-]
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Pureza y Documentación

Purity: 98.5%

SDS (644 KB)

COA (249 KB)

Instrucciones de manejo (2659 KB)
Referencias
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Picoplatin Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Picoplatin181630-15-9AMD473 ZD0473AMD 473AMD-473ZD0473ZD 0473ZD-0473DNA/RNA SynthesisPlatinumantineoplasticcircumvent thioldrug resistanceglutathioneGSHDNAInhibitorinhibitorinhibit

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Nombre del producto:
Picoplatin
Cat. No.:
HY-131468
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SAFETY DATA SHEET (SDS)

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