181630-15-9
181630-15-9
Chemical Structure
Picoplatin
Synonym(s): AMD473; ZD0473
- CAS No.: 181630-15-9
- Formula:C6H10Cl2N2Pt
- Molecular Weight:376.15
InChIKey: IIMIOEBMYPRQGU-UHFFFAOYSA-L
SMILES: [Cl-][Pt+2]([N]1=C(C)C=CC=C1)([NH3])[Cl-]
Biological Activity: Picoplatin (AMD473) is a platinum-based antineoplastic agent. Picoplatin is specifically to circumvent thiol-mediated drug resistance by sterically hindering its reaction with glutathione (GSH) while still retaining the ability to form cytotoxic lesions with DNA[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Picoplatin | 98.5% | Picoplatin (AMD473) is a platinum-based antineoplastic agent. Picoplatin is specifically to circumvent thiol-mediated drug resistance by sterically hindering its reaction with glutathione (GSH) while still retaining the ability to form cytotoxic lesions with DNA. | ||||||||||||||||||||
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References
Keywords
