2. GPCR/G Protein Neuronal Signaling
  3. CaSR 5-HT Receptor
  4. Poly-D-lysine hydrobromide (MW 150000-300000)

Poly-D-lysine hydrobromide (MW 150000-300000)  (Synonyms: PDLHB (MW 150000-300000))

Cat. No.: HY-139201E
COA
SDS
Handling Instructions Technical Support

Poly-D-lysine hydrobromide (MW 150000-300000) is a synthetic polymer composed of D-lysine residues and is one of the most widely used matrices in neural cell culture applications. Poly-D-lysine hydrobromide (MW 150000-300000) can be used as a non-specific cell adhesion enhancer. Poly-D-lysine hydrobromide (MW 30000-70000) is an orally active CaSR agonist peptide that indirectly activates the 5-HT₃ receptor signaling pathway, delaying gastric emptying and thereby slowing the rate at which glucose enters the small intestine and is absorbed.

For research use only. We do not sell to patients.

Poly-D-lysine hydrobromide (MW 150000-300000)

Poly-D-lysine hydrobromide (MW 150000-300000) Chemical Structure

CAS No. : 27964-99-4

Size Price Stock Quantity
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 Customer Validation

Poly-D-lysine hydrobromide (MW 150000-300000) Related Antibodies

Top Publications Citing Use of Products

View All 5-HT Receptor Isoform Specific Products:

View All Isoforms
5-HT Receptor 5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Poly-D-lysine hydrobromide (MW 150000-300000) is a synthetic polymer composed of D-lysine residues and is one of the most widely used matrices in neural cell culture applications. Poly-D-lysine hydrobromide (MW 150000-300000) can be used as a non-specific cell adhesion enhancer. Poly-D-lysine hydrobromide (MW 30000-70000) is an orally active CaSR agonist peptide that indirectly activates the 5-HT₃ receptor signaling pathway, delaying gastric emptying and thereby slowing the rate at which glucose enters the small intestine and is absorbed[1][2].

In Vitro

Poly-D-lysine hydrobromide (0.1 mg/mL,0-24 h) promotes the formation of strong and stable adhesion plaques in primary cultured rat pulmonary artery smooth muscle cells (PASMCs), while restricting their migration ability[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Poly-D-lysine hydrobromide (MW 150000-300000) Related Antibodies

Cell Migration Assay[2]

Cell Line: PASMCs
Concentration: 0.1 mg/mL
Incubation Time: 0, 8, 12, 24 h
Result: Inhibited cell migration.
In Vivo

Poly-D-lysine hydrobromide (MW 30000-70000) (50 mg/kg, i.g or duodenum administration, single dose) reduces the peak blood glucose level after oral glucose administration[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Oral glucose tolerance test (OGTT) and intraperitoneal glucose tolerance test (IPGTT) established in male Sprague-Dawley rats (7 weeks old), weighing 210-230 g[1]
Dosage: 50 mg/kg
Administration: Oral gavage (i.g.) or duodenum administration, single dose
Result: Significantly reduced the peak blood glucose level after oral glucose administration, but had no significant hypoglycemic effect in the intraperitoneal glucose tolerance test (IPGTT).
Delayed the absorption of glucose by slowing down the rate at which food moves from the stomach to the small intestine.
Molecular Weight

150000-300000

Formula

(C6H14N2O2)n.xHBr
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CNC(CCCCN)C(N[C@@H](CCCCN)C(N[C@H](CCCCN)C(C)=O)=O)=O.[x].Br.[n]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Poly-D-lysine hydrobromide (MW 150000-300000) Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Poly-D-lysine hydrobromide (MW 150000-300000)27964-99-4PDLHB (MW 150000-300000)CaSR5-HT ReceptorCalcium-sensing receptor Serotonin Receptor5-hydroxytryptamine Receptorcalcium-sensing receptorglycemic controldietary peptidesgastric emptyingInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Poly-D-lysine hydrobromide (MW 150000-300000)
Cat. No.:
HY-139201E
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (252 KB) Français - FR (252 KB) Deutsch - DE (252 KB) Norwegian - NO (252 KB) Español - ES (252 KB) Swedish - SV (252 KB) Italian - IT (252 KB) Korean - KR (252 KB) Portuguese - PT (252 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.