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Results for "

1,6-Di-O-galloyl-β-D-glucose

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

11

Natural
Products

Art. -Nr. Produktname Target Forschungsgebiete Chemical Structure
  • HY-N0527
    Pentagalloylglucose
    10+ Cited Publications

    Penta-O-galloyl-β-D-glucose; 1,2,3,4,6-Pentagalloyl glucose

    		 JAK Keap1-Nrf2 Apoptosis β-catenin Reactive Oxygen Species (ROS) E1/E2/E3 Enzyme Neurological Disease Inflammation/Immunology Cancer
    Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) is an orally active gallic tannin compound and an inducer of apoptosis and autophagy. Pentagalloglucose induces cell apoptosis and autophagy through the GSK3β/β-catenin pathway. Pentagalloylglucose inhibits UBE2T-mediated p53 ubiquitination, upregulates p53, downregulates RRM1/RRM2 in pancreatic cancer organoids. Pentagalloglucose has antioxidant, anti mutagenic, anti-inflammatory, anticonvulsant, cardioprotective, anti allergic, cholesterol lowering, and anti-tumor activities .
    Pentagalloylglucose
  • HY-133708
    β-Glucogallin
    1 Publications Verification

    Glucogallin; 1-O-galloyl-β-D-glucose

    		 Aldose Reductase Reactive Oxygen Species (ROS) NF-κB PDGFR SOD Neurological Disease Metabolic Disease
    β-Glucogallin is an orally active and selective aldose reductase (AKR1B1) inhibitor with an IC50 value of 58 μM when using Glyceraldehyde (HY-128748) as AKR1B1 substrate. β-Glucogallin reduces ROS, PDGF, RAGE, and NF-κB. β-Glucogallin increases SOD. β-Glucogallin has antioxidant and hepatoprotective effects. β-Glucogallin can be used in retinal research .
    β-Glucogallin
  • HY-N6006
    1,3,6-Tri-O-galloyl-beta-D-glucose

    1,3,6-Tri-O-galloyl-β-D-glucose

    		 Others Others
    1,3,6-Tri-O-galloyl-beta-D-glucose is a non-covalent inhibitor of tyrosinase (TYR), which can block the rate-limiting step of melanin synthesis and inhibit melanin deposition. 1,3,6-Tri-O-galloyl-beta-D-glucose has antioxidant and anti-inflammatory activities and can be used as a natural active ingredient to develop anti-freckle and whitening skin care products .
    1,3,6-Tri-O-galloyl-beta-D-glucose
  • HY-W719041
    1,6-Di-O-galloyl-β-D-glucose

    		HIV Reverse Transcriptase Infection
    1,6-Di-O-galloyl-β-D-glucose is a compound found in the fruit of Phyllanthus emblica. 1,6-Di-O-galloyl-β-D-glucose has HIV-1 reverse transcriptase (RT) inhibitory activity with an IC50 value of 270 μM. The inhibitory mechanism of 1,6-Di-O-galloyl-β-D-glucose is competitive inhibition of the template primer and non-competitive inhibition of the substrate (dTTP). 1,6-Di-O-galloyl-β-D-glucose can be used in anti-HIV research .
    1,6-Di-O-galloyl-β-D-glucose
  • HY-N11285
    1,2,6-Tri-O-galloyl-β-D-glucose

    		Others Cardiovascular Disease
    1,2,6-Tri-O-galloyl-β-D-glucose is a polygalloylglucose found in the roots and rhizomes of Sanguisorba officinalis .
    1,2,6-Tri-O-galloyl-β-D-glucose
  • HY-N15572
    1,2,4,6-Tetra-O-galloyl-β-D-glucose

    		SOD Inflammation/Immunology
    1,2,4,6-Tetra-O-galloyl-β-D-glucose is an antioxidant found in Eucalyptus globulus. 1,2,4,6-Tetra-O-galloyl-β-D-glucose has significant superoxide dismutase (SOD)-like antioxidant activity (EC50: 1.55 μM). 1,2,4,6-Tetra-O-galloyl-β-D-glucose can inhibit tyrosinase (IC50: 0.59 mM) and hyaluronidase (IC50: 0.68 mM). 1,2,4,6-Tetra-O-galloyl-β-D-glucose can be used in food antioxidants, cosmetics anti-melanogenesis and anti-allergy/anti-inflammatory research .
    1,2,4,6-Tetra-O-galloyl-β-D-glucose
  • HY-N0527R
    Pentagalloylglucose (Standard)

    Penta-O-galloyl-β-D-glucose (Standard); 1,2,3,4,6-Pentagalloyl glucose (Standard)

    		 Reference Standards JAK Keap1-Nrf2 Apoptosis β-catenin Reactive Oxygen Species (ROS) Neurological Disease Inflammation/Immunology Cancer
    Pentagalloylglucose (Standard) is the analytical standard of Pentagalloylglucose. This product is intended for research and analytical applications. Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) is an orally active gallic tannin compound and an inducer of apoptosis and autophagy. Pentagalloglucose induces cell apoptosis and autophagy through the GSK3β/β-catenin pathway. Pentagalloylglucose inhibits UBE2T-mediated p53 ubiquitination, upregulates p53, downregulates RRM1/RRM2 in pancreatic cancer organoids. Pentagalloglucose has antioxidant, anti mutagenic, anti-inflammatory, anticonvulsant, cardioprotective, anti allergic, cholesterol lowering, and anti-tumor activities .
    Pentagalloylglucose (Standard)
  • HY-N6006R
    1,3,6-Tri-O-galloyl-beta-D-glucose (Standard)

    1,3,6-Tri-O-galloyl-β-D-glucose (Standard)

    		 Reference Standards Others Others
    1,3,6-Tri-O-galloyl-beta-D-glucose (Standard) is the analytical standard of 1,3,6-Tri-O-galloyl-beta-D-glucose. This product is intended for research and analytical applications. 1,3,6-Tri-O-galloyl-beta-D-glucose (1,3,6-Tri-O-galloyl-β-D-glucose) is a phenolic compound in Black Walnut Kernels .
    1,3,6-Tri-O-galloyl-beta-D-glucose (Standard)
  • HY-N16527
    7-O-Galloyl-D-sedoheptulose

    		TNF Receptor Interleukin Related NADPH Oxidase Reactive Oxygen Species (ROS) NF-κB COX NO Synthase JNK AP-1 TGF-β Receptor Metabolic Disease
    7-O-Galloyl-D-sedoheptulose is an orally effective polyphenolic compound. 7-O-Galloyl-D-sedoheptulose lowers the serum levels of glucose, leptin, insulin, C-peptide, resistin, TNF-α, IL-6, and increases the serum level of adiponectin. 7-O-Galloyl-D-sedoheptulose significantly reduces the levels of ROS and lipid peroxidation products (TBARS) by down-regulating the protein expression of NADPH oxidase subunit Nox-4 and p22phox. 7-O-Galloyl-D-sedoheptulose down-regulates NF-κB and related pro-inflammatory factors (COX-2, iNOS), inhibits the phosphorylation of JNK and the activity of its downstream AP-1. 7-O-Galloyl-D-sedoheptulose reduces the expression of TGF-β1 and fibronectin, indicating its potential in anti-tissue fibrosis. 7-O-Galloyl-D-sedoheptulose can be used for the study of type 2 diabetes and its hepatic and pancreatic complications .
    7-O-Galloyl-D-sedoheptulose
  • HY-N7963
    1-O-Galloyl-2-O-cinnamoyl-glucose

    		Others Others
    1-O-Galloyl-2-O-cinnamoyl-glucose is a natural compound that could be found in R. palmatum L. .
    1-O-Galloyl-2-O-cinnamoyl-glucose
  • HY-N17215
    3,4,6-Tri-O-galloyl-D-glucose

    3,4,6-Trigalloylglucose

    		 Amylases Glycosidase Metabolic Disease Inflammation/Immunology
    3,4,6-Tri-O-galloyl-D-glucose (3,4,6-Trigalloylglucose) is an α-amylase (porcine α-amylase IC50 = 334.6 μM; Ki = 307.5 μM) and α-glucosidase (yeast α-glucosidase IC50 = 46.5 μM; Ki = 39.9 μM) mixed type inhibitor. 3,4,6-Tri-O-galloyl-D-glucose exhibits free radical scavenging ability, ferric-reducing power, and antioxidant activity. 3,4,6-Tri-O-galloyl-D-glucose can be used for the research of diabetes .
    3,4,6-Tri-O-galloyl-D-glucose

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