7-O-Galloyl-D-sedoheptulose
7-O-Galloyl-D-sedoheptulose is an orally effective polyphenolic compound. 7-O-Galloyl-D-sedoheptulose lowers the serum levels of glucose, leptin, insulin, C-peptide, resistin, TNF-α, IL-6, and increases the serum level of adiponectin. 7-O-Galloyl-D-sedoheptulose significantly reduces the levels of ROS and lipid peroxidation products (TBARS) by down-regulating the protein expression of NADPH oxidase subunit Nox-4 and p22phox. 7-O-Galloyl-D-sedoheptulose down-regulates NF-κB and related pro-inflammatory factors (COX-2, iNOS), inhibits the phosphorylation of JNK and the activity of its downstream AP-1. 7-O-Galloyl-D-sedoheptulose reduces the expression of TGF-β1 and fibronectin, indicating its potential in anti-tissue fibrosis. 7-O-Galloyl-D-sedoheptulose can be used for the study of type 2 diabetes and its hepatic and pancreatic complications.
For research use only. We do not sell to patients.
- CAS No.: 233690-85-2
- Formula: C14H18O11
- Molecular Weight:362.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All AP-1 Isoforms
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Biological Activity
Chemical Information
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CAS No. 233690-85-2
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Molecular Weight 362.29
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Formula C14H18O11
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SMILES
OCC([C@@H](O)[C@H](O)[C@H](O)[C@H](O)COC(C1=CC(O)=C(C(O)=C1)O)=O)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)