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Aspergillus sp.

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (2) Apoptosis (1) Bacterial (5) Biochemical Assay Reagents (1) Calcium Channel (1) COX (1) Drug Derivative (2) Endogenous Metabolite (5) Fungal (9) HSV (1) Influenza Virus (1) Interleukin Related (1) Neurokinin Receptor (1) NF-κB (1) NO Synthase (1) NOD-like Receptor (NLR) (1) p38 MAPK (1) Reactive Oxygen Species (ROS) (1) Reference Standards (1) VEGFR (1)
By Research Areas:	Cancer (3) Infection (15) Inflammation/Immunology (4) Metabolic Disease (1) Neurological Disease (1)

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Peptides

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Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113542

Blasticidin A 1 Publications Verification (+)-Blasticidin A	Antibiotic Fungal	Infection
Blasticidin A ((+)-Blasticidin A) is a tetraamide acid derivative antibiotic produced by Streptomyces griseochromogenes, as well as a selective inhibitor of aflatoxin production. Blasticidin A exhibits antimicrobial activity against yeast. Blasticidin A can be used in research related to aflatoxin contamination (infection by Aspergillus sp.) .

HY-N7078

Spiculisporic acid	Others	Others
Spiculisporic acid is a γ-butenolide isolated from the cultue of Aspergillus sp . Spiculisporic acid is a microbial biosurfactant and has anti-oxidative stress actions .

HY-N16411

Carneamide A	Others	Others
Carneamide A is a prenylated indole alkaloid produced by a marine-derived Aspergillus sp .

HY-N8509

Chevalone E Deacetylchevalone C	Bacterial	Infection
Chevalone E (Deacetylchevalone C) (Compound 3) is a meroditerpenoid. Chevalone E can be isolated from the fungus Aspergillus similanensis sp. Chevalone E has a synergic effect with Oxacillin (HY-B0925A) and Ampicillin (HY-B0522) against MRSA .

HY-P11342

Verlamelin A	Fungal HSV	Infection
Verlamelin A is a macrocyclic depsipeptide with antifungal and antiviral activity. Verlamelin A shows antifungal activity toward Aspergillus versicolor and Curvularia australiensis and also has antiviral activity toward HSV-1 (IC₅₀ = 16.7 μM). Verlamelin A is isolated from the entomopathogenic fungus Lecanicillium sp. Verlamelin A is useful for antifungal and antiviral research .

HY-N16404

Asperindole A	Apoptosis Endogenous Metabolite	Cancer
Asperindole A is an indole-diterpene alkaloid. Asperindole A can be isolated from fungus Aspergillus sp. KMM 4676. Asperindole A induces Apoptosis. Asperindole A exerts cytotoxic activity against hormone-resistant and hormone-sensitive prostate cancer cells .

HY-N8846

dl-Aloesol	Fungal	Infection
dl-Aloesol is a natural product that can be isolated from fungus Aspergillus sp. Aspergillus sp metabolites has cytotoxic, antibacterial, free radical scavenging, anti-parasitic, antiviral and antiproliferative activities, etc .

HY-P5569

SP-B peptide	Fungal	Infection
SP-B peptide is an antimicrobial peptide. SP-B peptide has antifungal activity against strains of Cryptococcus neoformans, Candida albicans and Aspergillus fumigatus

HY-125538

Deoxybrevianamide E	Endogenous Metabolite	Inflammation/Immunology
Deoxybrevianamide E, an indole alkaloid, is a biosynthetic precursor for advanced metabolites isolated from the marine-derived Aspergillus sp. .

HY-N12389

Quellenin	Fungal	Infection
Quellenin is an anti-saprolegnia compound. Quellenin can be isolated from deep-sea fungus Aspergillus sp. YK-76

HY-N14122

Cladosporide B	Fungal	Infection
Cladosporide B is found in the strain of Cladosporium sp. IFM 49189. Cladosporide B has slightly stronger anti-Aspergillus fumigatus activity than Cladosporide A .

HY-E70119D

*Pectate Lyase, Aspergillus* sp.**	Biochemical Assay Reagents	Metabolic Disease
Pectate Lyase, Aspergillus sp. (EC 4.2.2.2) is an enzyme involved in the maceration and soft rotting of plant tissue. Pectate lyase is responsible for the eliminative cleavage of pectate, yielding oligosaccharides with 4-deoxy-α-D-mann-4-enuronosyl groups at their non-reducing ends.

HY-123161

JBIR-15	Drug Derivative	Others
JBIR-15 is a new aspochracin derivative. JBIR-15 is isolated from a sponge-derived fungus, Aspergillus sclerotiorum Huber Sp080903f04 .

HY-N14121

Cladosporide A	Fungal	Infection
Cladosporide A is found in the strain of Cladosporium sp. IFM 49189. Cladosporide A inhibits Aspergillus fumigatus with IC₅₀ of 0.5-4.0 μg/mL, but it has no effect on other filamentous fungi .

HY-113614

Tetrahydrobostrycin	Bacterial	Infection
Tetrahydrobostrycin is a secondary metabolite from Aspergillus sp., which exhibits a weak inhibitory activity against Staphylococcus aureus and Escherichia coli (100 mg/disc with the inhibition zones of 15 and 9.2 mm in diameter) .

HY-N16401

Aspergillumarin B	Bacterial Drug Derivative	Infection
Aspergillumarin B (Compound 2) is a derivative of dihydroisocoumarin. Aspergillumarin B can be isolated from the endophytic fungus Aspergillus sp.. Aspergillumarin B has a weak antibacterial activity against Staphylococcus aureus and Bacillus subtilis .

HY-109125A

Amcipatricin L-aspartate SPA-S-753; SPA-S-752 L-aspartate	Antibiotic Fungal	Infection
Amcipatricin diaspartate (SPA-S-753) is a semi-synthetic polyene antibiotic, with potent broad-spectrum antifungal activity .

HY-N9220

6-Epi-albassitriol	Influenza Virus	Infection
6-Epi-albassitriol can be isolated from Aspergillus sp. FH-A 6357. 6-Epi-albassitriol inhibits the cholesterol synthesis with an inhibition rate of 40% at a concentration of 10 nM in HepG2. 6-Epi-albassitriol exhibits antiviral activity against influenza A virus and parainfluenza virus with MIC of 44.4-133.3 µg/mL .

HY-N16405

Asperindole B	Others	Others
Asperindole B is an indole-diterpene alkaloid that can be isolated from Aspergillus sp.KMM 4676 .

HY-N6189

MBL-1	Endogenous Metabolite COX p38 MAPK NF-κB NOD-like Receptor (NLR) NO Synthase Reactive Oxygen Species (ROS) Interleukin Related	Infection Inflammation/Immunology
MBL-1 is an orally active anti-inflammatory agent. MBL-1 can be isolated from the fermentation broth of Aspergillus sp. derived from gorgonians. MBL-1 inhibits the activity of the hCOX-2 protein with an IC₅₀ of 5.77 μM. MBL-1 reduces the production of key pro-inflammatory mediators such as NO, ROS, IL-1β and IL-18 by inhibiting the MAPK/NF-κB and NLRP3 signaling pathways. MBL-1 exerts a protective effect against DSS-induced colitis. MBL-1 can be used for the research of ulcerative colitis .

HY-N7078R

Spiculisporic acid (Standard)	Others Reference Standards	Others
Spiculisporic acid (Standard) is the analytical standard of Spiculisporic acid (HY-N7078). This product is intended for research and analytical applications. Spiculisporic acid is a γ-butenolide isolated from the cultue of Aspergillus sp . Spiculisporic acid is a microbial biosurfactant and has anti-oxidative stress actions .

HY-N16428

Neoaspergillic acid NSC 356436	Endogenous Metabolite Fungal Bacterial	Infection Cancer
Neoaspergillic acid (NSC 356436) (Compound 2) is a microbial secondary metabolite. Neoaspergillic acid can be isolated from the endophytic fungus Aspergillus sp. SPH2. Neoaspergillic acid has potent antifungal activity against Alternaria alternata, Botrytis cinerea and Fusarium oxysporum. Neoaspergillic acid appears during the exponential phase of fungal growth. Neoaspergillic acid also antitumor and antibacterial effects .

HY-N16448

Xanthoascin	Bacterial	Infection
Xanthoascin (Compound 1) is a natural phenolic metabolite with strong anti plant pathogen activity. Xanthoascin can be extracted from the solid fermentation product of endophytic fungus Aspergillus sp. IFB-YXS isolated from Ginkgo biloba leaves. Xanthoascin has a MIC of 0.3125 µg/mL against Clavibacter michiganense subsp. Sepedonicus and moderate inhibitory activity against other pathogens (MIC = 5-20 µg/mL). Xanthoascin can disrupt the permeability of bacterial cell membranes, leading to nucleic acid leakage .

HY-182569

FR 111142	VEGFR	Inflammation/Immunology Cancer
FR 111142 is an angiogenesis inhibitor (IC₅₀ = 18.4 μM) and has anti-inflammatory activity (IC₅₀ = 20.6 μM). FR 111142 inhibits capillary-like tube formation as well as nitric oxide production in LPS (HY-D1056)-activated murine macrophages. FR 111142 enhances catabolism of low-density lipoprotein (LDL). FR 111142 does not induce significant cytotoxicity in human endothelial progenitor cells, nor affect cell viability of murine macrophages. FR 111142 can be used for the research of cancer, inflammatory diseases .

HY-N9554

WIN-64821	Neurokinin Receptor Endogenous Metabolite Calcium Channel	Neurological Disease Inflammation/Immunology
WIN-64821 is a secondary metabolite produced by Aspergillus species, and acts as a Neurokinin Receptor antagonist. The K_i values of WIN-64821 for NK1, NK2 and NK3 receptors are 0.24 (human astrocytoma cells), 0.26 (rat duodenum) and 15.2 (guinea pig forebrain) μM, respectively. WIN-64821 inhibits apamin-induced contraction of rat vas deferens, blocks substance P-induced contraction of guinea pig ileum and Ca ²⁺ efflux in human astrocytoma cells. WIN-64821 is applicable to analgesic and anti-inflammatory research .

Cat. No.	Product Name	Target	Research Area

HY-P11342

Verlamelin A	Fungal HSV	Infection
Verlamelin A is a macrocyclic depsipeptide with antifungal and antiviral activity. Verlamelin A shows antifungal activity toward Aspergillus versicolor and Curvularia australiensis and also has antiviral activity toward HSV-1 (IC₅₀ = 16.7 μM). Verlamelin A is isolated from the entomopathogenic fungus Lecanicillium sp. Verlamelin A is useful for antifungal and antiviral research .

HY-P5569

SP-B peptide	Fungal	Infection
SP-B peptide is an antimicrobial peptide. SP-B peptide has antifungal activity against strains of Cryptococcus neoformans, Candida albicans and Aspergillus fumigatus

Spiculisporic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Marine natural products Other Diseases Marine microorganism Disease Research Fields Source Classification	Others
Spiculisporic acid is a γ-butenolide isolated from the cultue of Aspergillus sp . Spiculisporic acid is a microbial biosurfactant and has anti-oxidative stress actions .

Carneamide A	Alkaloids Microorganisms Indole Alkaloids Source Classification	Others
Carneamide A is a prenylated indole alkaloid produced by a marine-derived Aspergillus sp .

Chevalone E Deacetylchevalone C	Microorganisms Terpenoids Diterpenoids Source Classification	Bacterial
Chevalone E (Deacetylchevalone C) (Compound 3) is a meroditerpenoid. Chevalone E can be isolated from the fungus Aspergillus similanensis sp. Chevalone E has a synergic effect with Oxacillin (HY-B0925A) and Ampicillin (HY-B0522) against MRSA .

Verlamelin A	Structural Classification Natural Products Microorganisms Source Classification	Fungal HSV
Verlamelin A is a macrocyclic depsipeptide with antifungal and antiviral activity. Verlamelin A shows antifungal activity toward Aspergillus versicolor and Curvularia australiensis and also has antiviral activity toward HSV-1 (IC₅₀ = 16.7 μM). Verlamelin A is isolated from the entomopathogenic fungus Lecanicillium sp. Verlamelin A is useful for antifungal and antiviral research .

Asperindole A	Structural Classification Alkaloids Microorganisms Terpenoids Diterpenoids Indole Alkaloids Source Classification	Apoptosis Endogenous Metabolite
Asperindole A is an indole-diterpene alkaloid. Asperindole A can be isolated from fungus Aspergillus sp. KMM 4676. Asperindole A induces Apoptosis. Asperindole A exerts cytotoxic activity against hormone-resistant and hormone-sensitive prostate cancer cells .

dl-Aloesol	Flavonoids Microorganisms Other Flavonoids Source Classification	Fungal
dl-Aloesol is a natural product that can be isolated from fungus Aspergillus sp. Aspergillus sp metabolites has cytotoxic, antibacterial, free radical scavenging, anti-parasitic, antiviral and antiproliferative activities, etc .

Deoxybrevianamide E	Alkaloids Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Marine natural products Endogenous metabolite Marine microorganism Inflammation/Immunology Disease Research Fields Indole Alkaloids Source Classification	Endogenous Metabolite
Deoxybrevianamide E, an indole alkaloid, is a biosynthetic precursor for advanced metabolites isolated from the marine-derived Aspergillus sp. .

Quellenin	Monophenols Microorganisms Phenols Source Classification	Fungal
Quellenin is an anti-saprolegnia compound. Quellenin can be isolated from deep-sea fungus Aspergillus sp. YK-76

Cladosporide B	Triterpenes Microorganisms Terpenoids Source Classification	Fungal
Cladosporide B is found in the strain of Cladosporium sp. IFM 49189. Cladosporide B has slightly stronger anti-Aspergillus fumigatus activity than Cladosporide A .

JBIR-15	Alkaloids Microorganisms Classification of Application Fields Other Alkaloids Other Diseases Disease Research Fields Source Classification	Drug Derivative
JBIR-15 is a new aspochracin derivative. JBIR-15 is isolated from a sponge-derived fungus, Aspergillus sclerotiorum Huber Sp080903f04 .

Cladosporide A	Triterpenes Microorganisms Terpenoids Source Classification	Fungal
Cladosporide A is found in the strain of Cladosporium sp. IFM 49189. Cladosporide A inhibits Aspergillus fumigatus with IC₅₀ of 0.5-4.0 μg/mL, but it has no effect on other filamentous fungi .

Tetrahydrobostrycin	Microorganisms Phenols Polyphenols Source Classification	Bacterial
Tetrahydrobostrycin is a secondary metabolite from Aspergillus sp., which exhibits a weak inhibitory activity against Staphylococcus aureus and Escherichia coli (100 mg/disc with the inhibition zones of 15 and 9.2 mm in diameter) .

Aspergillumarin B	Natural Products Microorganisms Source Classification	Bacterial Drug Derivative
Aspergillumarin B (Compound 2) is a derivative of dihydroisocoumarin. Aspergillumarin B can be isolated from the endophytic fungus Aspergillus sp.. Aspergillumarin B has a weak antibacterial activity against Staphylococcus aureus and Bacillus subtilis .

Asperindole B	Structural Classification Alkaloids Microorganisms Terpenoids Diterpenoids Indole Alkaloids Source Classification	Others
Asperindole B is an indole-diterpene alkaloid that can be isolated from Aspergillus sp.KMM 4676 .

Spiculisporic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Marine natural products Marine microorganism Source Classification	Others Reference Standards
Spiculisporic acid (Standard) is the analytical standard of Spiculisporic acid (HY-N7078). This product is intended for research and analytical applications. Spiculisporic acid is a γ-butenolide isolated from the cultue of Aspergillus sp . Spiculisporic acid is a microbial biosurfactant and has anti-oxidative stress actions .

Neoaspergillic acid NSC 356436	Natural Products Microorganisms Source Classification	Endogenous Metabolite Fungal Bacterial
Neoaspergillic acid (NSC 356436) (Compound 2) is a microbial secondary metabolite. Neoaspergillic acid can be isolated from the endophytic fungus Aspergillus sp. SPH2. Neoaspergillic acid has potent antifungal activity against Alternaria alternata, Botrytis cinerea and Fusarium oxysporum. Neoaspergillic acid appears during the exponential phase of fungal growth. Neoaspergillic acid also antitumor and antibacterial effects .

Xanthoascin	Monophenols Microorganisms Phenols Source Classification	Bacterial
Xanthoascin (Compound 1) is a natural phenolic metabolite with strong anti plant pathogen activity. Xanthoascin can be extracted from the solid fermentation product of endophytic fungus Aspergillus sp. IFB-YXS isolated from Ginkgo biloba leaves. Xanthoascin has a MIC of 0.3125 µg/mL against Clavibacter michiganense subsp. Sepedonicus and moderate inhibitory activity against other pathogens (MIC = 5-20 µg/mL). Xanthoascin can disrupt the permeability of bacterial cell membranes, leading to nucleic acid leakage .

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Aspergillus sp.

Inhibitors & Agonists

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Natural
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