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Epstein-Barr virus early antigen (EBV-EA) activation

" in MedChemExpress (MCE) Product Catalog:

16

Inhibitors & Agonists

14

Natural
Products

Targets Recommended:
Art. -Nr. Produktname Target Forschungsgebiete Chemical Structure
  • HY-N6033
    Ferruginol

    (+)-Ferruginol

    		 EBV HSV Apoptosis Infection Cardiovascular Disease Neurological Disease Cancer
    Ferruginol ((+)-Ferruginol), a natural diterpenoid, is an inhibitor of the activation of Epstein-Barr virus early antigen (EBV-EA). Ferruginol inhibits the growth of thyroid cancer cells through the induction of mitochondrial apoptosis. Ferruginol has antitumor, cardioprotective, antioxidant, gastroprotective, and neuroprotective activities .
    Ferruginol
  • HY-W743654
    Capsorubin

    		Apoptosis Cancer
    Capsorubin is a carotenoid found in peppers with multiple biological activities. Capsorubin (167 μM) inhibits lipid peroxidation induced by 2,2'-azobis(2,4-dimethylvaleronitrile) (AMVN) in vitro. Capsorubin (1 μM) reduces UVB-induced DNA strand breaks and apoptosis in human dermal fibroblasts. Capsorubin also inhibits Epstein-Barr virus early antigen (EBV-EA) activation induced by phorbol 12-myristate 13-acetate in Raji cells, a marker of tumorigenesis.
    Capsorubin
  • HY-N7041
    11-Oxomogroside IIa

    		EBV HSV Infection
    11-Oxomogroside IIa (11-oxomogroside II A1) is a cucurbitane glycoside extracted from the fruits of Siraitia grosVenorii. 11-Oxomogroside IIa has inhibitory effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), shows weak inhibitory effects on activation of (+/-)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor .
    11-Oxomogroside IIa
  • HY-N15402
    Porritoxin

    		EBV Infection
    Porritoxin (compound 1 ) is a metabolite of Alternaria porri. Porritoxin shows the inhibitory effect on Epstein-Barr virus early antigen (EBV-EA) activation induced by TPA (HY-18739) .
    Porritoxin
  • HY-W743654R
    Capsorubin (Standard)

    		Apoptosis Reference Standards Cancer
    Capsorubin (Standard) is the analytical standard of Capsorubin. This product is intended for research and analytical applications. Capsorubin is a carotenoid found in peppers with multiple biological activities. Capsorubin (167 μM) inhibits lipid peroxidation induced by 2,2'-azobis(2,4-dimethylvaleronitrile) (AMVN) in vitro. Capsorubin (1 μM) reduces UVB-induced DNA strand breaks and apoptosis in human dermal fibroblasts. Capsorubin also inhibits Epstein-Barr virus early antigen (EBV-EA) activation induced by phorbol 12-myristate 13-acetate in Raji cells, a marker of tumorigenesis.
    Capsorubin (Standard)
  • HY-N11009
    11-Oxomogroside II A1

    		EBV Infection
    11-Oxomogroside II A1 (compound 7) is an oxidized cucurbitin. It can be isolated from the ethanol extract of Rohanberry fruit. 11-Oxomogroside II A1 inhibits the activation of Epstein-Barr virus (EBV) early antigen (EBV-EA) induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). 11-Oxomogroside II A1 also weakly inhibits the activation of (±)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor .
    11-Oxomogroside II A1
  • HY-N11020
    Cabenoside D

    		EBV Infection Inflammation/Immunology
    Cabenoside D (compound 8) is a triterpenoid glycoside, which can be isolated from the methanol extract of lichen root. Cabenoside D shows anti-inflammatory activity and inhibits inflammation induced by 12-O-tetracylacyl hormone-13-acetate (TPA) in mice. Cabenoside D also inhibits TPA-induced Epstein-Barr virus (EBV) early antigen (EBV-EA) activation .
    Cabenoside D
  • HY-130789
    Cimigenol-3-one

    		EBV Infection
    Cimigenol-3-one inhibits Epstein-Barr virus early antigen (EBV-EA) activation .
    Cimigenol-3-one
  • HY-N4155
    2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid

    		EBV HIV Protease HSV Infection Cancer
    2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid, a natural ursane-type triterpene, is a potent inhibitor of HIV protease (HIV Protease). 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid is also an inhibitor of the activation of Epstein-Barr virus early antigen (EBV-EA). 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid displays an inhibitory activity against nitric oxide production in Lipopolysaccharide (Lipopolysaccharides)-activated RAW 264.7 cells .
    2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid
  • HY-N3254
    Minumicrolin

    Murpanidin; (+)-Murpanidin

    		 HSV EBV Infection
    Minumicrolin is a plant growth inhibitor. Minumicrolin can be isolated from Murraya paniculata. Minumicrolin inhibits Epstein-Barr virus early antigen (EBV-EA) activation .
    Minumicrolin
  • HY-N8041
    Mogroside III A2

    		HSV Infection
    Mogroside III A2 is a cucurbitane glycoside. Mogroside III A2 can inhibit Epstein-Barr virus early antigen (EBV-EA) activation. Mogroside III A2 shows weak inhibitory effects on activation of NOR 1 .
    Mogroside III A2
  • HY-N12978
    Benzyl β-gentiobioside

    		Others Cancer
    Benzyl β-gentiobioside is a phenyl alcohol glycoside found in peach kernels (Prunus persica seeds). Benzyl β-gentiobioside has anti-tumor promoting activity by inhibiting TPA (12-O-tetradecanoylphorbol 13-acetate, a tumor promoter)-induced Epstein-Barr virus early antigen (EBV-EA) activation .
    Benzyl β-gentiobioside
  • HY-W714047
    Valerianol

    		EBV Bacterial Infection
    Valerianol is a sesquiterpene alcohol with anticancer, antibacterial, and antiviral activities. Valerianol selectively inhibits TPA (HY-18739)-induced Epstein-Barr virus early antigen (EBV-EA) activation (IC50=300 μM). Valerianol inhibits tumor promoter-mediated EBV-EA activation and also inhibits pathogenic bacteria such as Staphylococcus aureus .
    Valerianol
  • HY-N13723
    Methyl lucidenate D

    		EBV Cancer
    Methyl lucidenate D is a selective inhibitor of Epstein-Barr virus early antigen (EBV-EA) activation with an IC50 of 290 mol ratio/32 pmol TPA. Methyl lucidenate D exerts potential anti-tumor promoting activity by inhibiting TPA-induced EBV-EA activation and maintains major Raji cell survival (70%) at effective concentrations. Methyl lucidenate D can be used in the field of cancer chemoprevention .
    Methyl lucidenate D
  • HY-N17638
    7-Oxomogroside V

    		EBV NO Synthase Infection Cancer
    7-Oxomogroside V is a cucurbitane-type glycoside isolated from the fruits of Siraitia grosvenorii. 7-Oxomogroside V inhibits the activation of Epstein-Barr virus early antigen (EBV-EA) induced by TPA (HY-18739). 7-Oxomogroside V also exerts weak inhibitory effects on the activation of the nitric oxide donor NOR 1. 7-Oxomogroside V is applicable to tumor-related research .
    7-Oxomogroside V
  • HY-N9752
    Mogroside II B

    		EBV Infection
    Mogroside II B is a cucurbitane-type glycoside with a sweet taste in water. Mogroside II B inhibits the activation of Epstein Barr virus early antigen (EBV-EA) induced by Phorbol 12-myristate 13-acetate (TPA) (HY-18739). Mogroside II B exerts weak inhibitory effects on the activation of the nitric oxide (NO) donor (NOR1) .
    Mogroside II B

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