Methyl lucidenate D
Methyl lucidenate D is a selective inhibitor of Epstein-Barr virus early antigen (EBV-EA) activation with an IC50 of 290 mol ratio/32 pmol TPA. Methyl lucidenate D exerts potential anti-tumor promoting activity by inhibiting TPA-induced EBV-EA activation and maintains major Raji cell survival (70%) at effective concentrations. Methyl lucidenate D can be used in the field of cancer chemoprevention.
For research use only. We do not sell to patients.
- CAS No.: 98665-09-9
- Formula: C30H40O8
- Molecular Weight:528.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Raji | IC50 |
290 molar ratio
Compound: 5b
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Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced EBV-early antigen activation in human Raji cells assessed per 32 pmol TPA by immunofluorescence technique
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced EBV-early antigen activation in human Raji cells assessed per 32 pmol TPA by immunofluorescence technique
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[PMID: 14695801] |
Chemical Information
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CAS No. 98665-09-9
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Molecular Weight 528.63
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Formula C30H40O8
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SMILES
C[C@@]12[C@](C3=C([C@@]4([C@@](C(C)(C(CC4)=O)C)([H])CC3=O)C)C([C@H]1OC(C)=O)=O)(C(C[C@]2([H])[C@H](C)CCC(OC)=O)=O)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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