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Isoforms Recommended:	Galectin-3

Results for "

Galectin-3

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Galectin (15) ADC Linker (2) Apoptosis (1) PROTAC Linkers (2)
By Research Areas:	Cancer (17) Inflammation/Immunology (2) Metabolic Disease (2)
Click Chemistry:	ADC Synthesis (2) PROTAC Synthesis (2) Alkynes (4)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Click Chemistry

Targets Recommended: Galectin

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-146808

Galectin-3 antagonist 1	Galectin	Cancer
Galectin-3 antagonist 1 (compound 15) is a potent and selective *Galectin-3* (Gal-3) antagonist with K_d value of 5.3 μM. Meanwhile, Galectin-3 antagonist 1 binds to various *Galectin* with K_d values of 250 μM (Gal-4N), 18 μM (Gal-4C), 450 μM (Gal-8C), respectively .

HY-144312

Galectin-3-IN-1	Galectin	Metabolic Disease Cancer
Galectin-3-IN-1 (Compound 1) is a potent multivalent inhibitor of *galectin-3* (Gal-3). Galectin-3 participates in many cancer-related metabolic processes . Galectin-3-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-146809

Galectin-3 antagonist 2	Galectin	Cancer
Galectin-3 is a β Galactoside specific carbohydrate recognition protein (lectin) has the ability to promote the migration of B cell precursor acute lymphoblastic leukemia (BCP-ALL) cells and withstand drug research.

HY-144313

Galectin-3-IN-2	Galectin	Metabolic Disease Cancer
Galectin-3-IN-2 (Compound 9) is a potent multivalent inhibitor of *galectin-3* (Gal-3; *IC₅₀*=8.3 μM). Galectin-3 participates in many cancer-related metabolic processes .

HY-163407

Galectin-3-IN-4	Galectin	Cancer
Galectin-3-IN-4 (compound 5) is a carboxamide analog. Galectin-3-IN-4 is a potent, selective, and orally bioavailable inhibitor of human and mouse *galectin-3, with IC₅₀* values of 21 and 167 nM for *hGal-3* and *mGal-3, respectively. Galectin-3-IN-4 has IC₅₀* values of 1580 and 2750 nM for hGal-1 and hGal-9, respectively .

HY-155191

Galectin-3/galectin-8-IN-1	Galectin	Inflammation/Immunology Cancer
Galectin-3/galectin-8-IN-1 (Compound 53) is a dual *Galectin-3* and *galectin-8* C-terminal domain inhibitor, with K_d values of 4.12 μM and 6.04 μM respectively. Galectin-3/galectin-8-IN-1 inhibits the MRC-5 lung fibroblast cells migration. Galectin-3/galectin-8-IN-1 can be used for research of cancer and tissue fibrosis .

HY-155192

Galectin-3/galectin-8-IN-2	Galectin	Inflammation/Immunology Cancer
Galectin-3/galectin-8-IN-2 (Compound 57) is a dual *Galectin-3* and *galectin-8* C-terminal domain inhibitor, with K_d values of 12.8 μM and 2.06 μM respectively. Galectin-3/galectin-8-IN-2 inhibits the MRC-5 lung fibroblast cells migration. Galectin-3/galectin-8-IN-2 can be used for research of cancer and tissue fibrosis .

HY-163405

Galectin-3-IN-3	Galectin	Cancer
Galectin-3-IN-3 (Compound 4) is an orally active and selective inhibitor of *Gal-3, with IC₅₀* values of 11 nM and 84 nM against *mGal-3* and *hGal-3* respectively .

HY-163082

GB1490

Galectin Cancer

GB1490 is an orally active galectin inhibitor with K_d values of 0.4 μM and 2.7 μM for galectin-1 and galectin-3, respectively .
HY-19940

Olitigaltin

Maximum Cited Publications

11 Publications Verification

TD139; GB0139

TD139 is an inhaled galectin-3 inhibitor with a K_d of 14 nM.

GB1490	Galectin	Cancer
GB1490 is an orally active *galectin* inhibitor with K_d values of 0.4 μM and 2.7 μM for galectin-1 and galectin-3, respectively .

Olitigaltin Maximum Cited Publications 11 Publications Verification TD139; GB0139
TD139 is an inhaled *galectin-3* inhibitor with a K_d of 14 nM.

HY-101157

Propargyl-PEG5-acid	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-114409

GB1107 5+ Cited Publications	Galectin	Cancer
GB1107 is a potent, selective, orally active inhibitor of **Galectin-3 (Gal-3) with a K_d** of 37 nM for human Galectin-3. GB1107 reduces human and mouse lung adenocarcinoma growth and blocks metastasis in the syngeneic model .

HY-147041

Selvigaltin

GB1211
Galectin Cancer

Selvigaltin (GB1211) is an orally available galectin-3 (Gal-3) inhibitor .

Selvigaltin GB1211	Galectin	Cancer
Selvigaltin (GB1211) is an orally available **galectin-3 (Gal-3)** inhibitor .

HY-130293

Propargyl-PEG4-CH2CH2-Boc	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG4-CH2CH2-Boc is a non-cleavable ADC linker that can be used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-CH2CH2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-P1592

G3-C12

1 Publications Verification

Galectin Cancer

G3-C12 is a galectin-3 binding peptide, with K_d of 88 nM, and shows anticancer activity.
HY-P1592A

G3-C12 TFA

1 Publications Verification

Galectin Cancer

G3-C12 (TFA) is a galectin-3 binding peptide, with K_d of 88 nM, and shows anticancer activity.

G3-C12 1 Publications Verification	Galectin	Cancer
G3-C12 is a galectin-3 binding peptide, with K_d of 88 nM, and shows anticancer activity.

G3-C12 TFA 1 Publications Verification	Galectin	Cancer
G3-C12 (TFA) is a galectin-3 binding peptide, with K_d of 88 nM, and shows anticancer activity.

HY-139831

Galectin-8-IN-1	Galectin	Cancer
Galectin-8-IN-1 is a selective ligand for the **galectin-8 N-terminal domain (galectin-8N)*, with a Kd of 48 μM and 15-fold selectivity over galectin-3* and even better selectivity over the other mammalian galectins.

HY-114440

Belapectin GR-MD-02	Galectin Apoptosis	Cancer
Belapectin (GR-MD-02) is a **Galectin-3 (Gal-3) inhibitor. Belapectin drives tumor-induced immunosuppression by inducing T cell Apoptosis*. Belapectin promotes tumor regression and improves survival of tumor-bearing mice through a CD8+ T cell-dependent mechanism. Belapectin binds to Gal*-3 with affinity K_i of 2.8 μM .

Cat. No.	Product Name	Target	Research Area

HY-P1592

G3-C12

1 Publications Verification

Galectin Cancer

G3-C12 is a galectin-3 binding peptide, with K_d of 88 nM, and shows anticancer activity.
HY-P1592A

G3-C12 TFA

1 Publications Verification

Galectin Cancer

G3-C12 (TFA) is a galectin-3 binding peptide, with K_d of 88 nM, and shows anticancer activity.

G3-C12 1 Publications Verification	Galectin	Cancer
G3-C12 is a galectin-3 binding peptide, with K_d of 88 nM, and shows anticancer activity.

G3-C12 TFA 1 Publications Verification	Galectin	Cancer
G3-C12 (TFA) is a galectin-3 binding peptide, with K_d of 88 nM, and shows anticancer activity.

Cat. No.	Product Name	Target	Research Area

HY-P990198

*Anti-Mouse/Human Mac-2/Galectin-3* Antibody (TIB-166)**	Inhibitory Antibodies	Others
Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse/human Mac-2/Galectin-3.

Species:	Human (3) Mouse (1) Cynomolgus (1)
Tag:	His (4) Tag Free (1)
Source:	HEK293 (3) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P700079AF

	*Animal-Free Galectin-3/LGALS3 Protein, Human (His)* Galectin-3; Gal-3; 35 kDa Lectin; Carbohydrate-Binding Protein 35; CBP 35; Galactose-Specific Lectin 3; Galactoside-Binding Protein; GALBP; IgE-Binding Protein; L-31; Laminin-Binding Protein; Lectin L-29; Mac-2 Antigen; LGALS3; MAC2	Human	E. coli
	The Galectin-3/LGALS3 protein is a galactose-specific lectin known for its diverse roles in cellular processes. It binds IgE and synergizes with α-3 and β-1 integrins to promote CSPG4-induced endothelial cell migration. Animal-Free Galectin-3/LGALS3 Protein, Human (His) is the recombinant human-derived animal-FreeGalectin-3/LGALS3 protein, expressed by E. coli , with N-His labeled tag. The total length of Animal-Free Galectin-3/LGALS3 Protein, Human (His) is 249 a.a., with molecular weight of ~27 kDa.

HY-P70309

	Galectin-3/LGALS3 Protein, Human 2 Publications Verification rHuGalectin-3; Galectin-3; Gal-3; 35 kDa Lectin; Carbohydrate-Binding Protein 35; CBP 35; Galactose-Specific Lectin 3; Galactoside-Binding Protein; GALBP; IgE-Binding Protein; L-31; Laminin-Binding Protein; Lectin L-29; Mac-2 Antigen; LGALS3; MAC2	Human	E. coli
	The Galectin-3/LGALS3 protein is a galactose-specific lectin known for its diverse roles in cellular processes. It binds IgE and synergizes with α-3 and β-1 integrins to promote CSPG4-induced endothelial cell migration. Galectin-3/LGALS3 Protein, Human is the recombinant human-derived Galectin-3/LGALS3 protein, expressed by E. coli , with tag free. The total length of Galectin-3/LGALS3 Protein, Human is 249 a.a., with molecular weight of ~30.0 kDa.

HY-P70171

	Galectin-3/LGALS3 Protein, Human (HEK293, His) rHuGalectin-3/LGALS3, His; Galectin-3; Gal-3; 35 kDa Lectin; Carbohydrate-Binding Protein 35; CBP 35; Galactose-Specific Lectin 3; Galactoside-Binding Protein; GALBP; IgE-Binding Protein; L-31; Laminin-Binding Protein; Lectin L-29; Mac-2 Antigen; LGALS3; MAC2	Human	HEK293
	The Galectin-3/LGALS3 protein is a galactose-specific lectin known for its diverse roles in cellular processes. It binds IgE and synergizes with α-3 and β-1 integrins to promote CSPG4-induced endothelial cell migration. Galectin-3/LGALS3 Protein, Human (HEK293, His) is the recombinant human-derived Galectin-3/LGALS3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Galectin-3/LGALS3 Protein, Human (HEK293, His) is 249 a.a., with molecular weight of 33-36 kDa.

HY-P77684

	Galectin-3/LGALS3 Protein, Mouse (HEK293, His) AGE-R3; CBP35; GAL3; Gal-3; galactin-3; GALBPCBP35; Galectin3; GALIG; L29; L31; Lectin L-29; LGALS2; LGALS3; Mac-2; MAC2GAL3	Mouse	HEK293
	Galectin-3/LGALS3 protein binds IgE and cooperates with integrins α-3 and β-1 to promote endothelial cell migration. It contributes to epithelial cell differentiation and acts as a splicing factor in the nucleus. Galectin-3/LGALS3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Galectin-3/LGALS3 protein, expressed by HEK293 , with C-His labeled tag. The total length of Galectin-3/LGALS3 Protein, Mouse (HEK293, His) is 263 a.a., with molecular weight of 40-50 kDa.

HY-P700996

	Galectin-3/LGALS3 Protein, Cynomolgus (HEK293, His) AGE-R3; CBP35; GAL3; Gal-3; galactin-3; GALBPCBP35; Galectin3; GALIG; L29; L31; Lectin L-29; LGALS2; LGALS3; Mac-2; MAC2GAL3	Cynomolgus	HEK293
	The Galectin-3/LGALS3 protein is a galactose-specific lectin known for its diverse roles in cellular processes. It binds IgE and synergizes with α-3 and β-1 integrins to promote CSPG4-induced endothelial cell migration. Galectin-3/LGALS3 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Galectin-3/LGALS3 protein, expressed by HEK293 , with N-His labeled tag. The total length of Galectin-3/LGALS3 Protein, Cynomolgus (HEK293, His) is 247 a.a., with molecular weight of 35-48 kDa.


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Cat. No.	Product Name	Application	Reactivity

HY-P80404

Galectin 3 Antibody Galectin-3; 35 kDa lectin; Carbohydrate binding protein 35; CBP 35; CBP35; GAL 3; GAL3; GAL-3; Galactose specific lectin 3; Galactose-specific lectin 3; Galactoside binding protein; Galactoside-binding protein; GALBP; Galectin3 internal gene,included; Galectin3; GALIG; GBP; IgE binding protein; IgE-binding protein; L 31; L 34; L-34 galactoside-binding lectin; L31; Laminin binding protein; Laminin-binding protein; Lectin galactose binding soluble 3; Lectin galactoside binding soluble 3; Lectin L 29; Lectin L-29; Lectin, galactose binding, soluble 3; LGALS 3; LGALS2; LGALS3; LGALS3 protein; MAC 2 antigen; Mac-2; MAC2; Macrophage galactose-specific lectin; MGC105387; LEG3_HUMAN.	WB, ICC/IF, FC, IHC-P	Human, Mouse
Galectin 3 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 26 kDa, targeting to Galectin 3. It can be used for WB,ICC/IF,FC,IHC-P assays with tag free, in the background of Human, Mouse.

Cat. No.	Product Name		Classification

HY-144312

Galectin-3-IN-1		Alkynes
Galectin-3-IN-1 (Compound 1) is a potent multivalent inhibitor of *galectin-3* (Gal-3). Galectin-3 participates in many cancer-related metabolic processes . Galectin-3-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-101157

Propargyl-PEG5-acid		Alkynes PROTAC Synthesis ADC Synthesis
Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130293

Propargyl-PEG4-CH2CH2-Boc		Alkynes ADC Synthesis PROTAC Synthesis
Propargyl-PEG4-CH2CH2-Boc is a non-cleavable ADC linker that can be used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-CH2CH2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-144313

Galectin-3-IN-2		Alkynes
Galectin-3-IN-2 (Compound 9) is a potent multivalent inhibitor of *galectin-3* (Gal-3; *IC₅₀*=8.3 μM). Galectin-3 participates in many cancer-related metabolic processes .

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