2. Immunology/Inflammation
  3. Galectin
  4. Selvigaltin

Selvigaltin  (Synonyms: GB1211)

Cat. No.: HY-147041 Purity: 98.72%
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Selvigaltin (GB1211) is an orally available galectin-3 (Gal-3) inhibitor.

For research use only. We do not sell to patients.

Selvigaltin Chemical Structure

Selvigaltin Chemical Structure

CAS No. : 1978336-95-6

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5 mg USD 850 In-stock
10 mg USD 1450 In-stock
25 mg USD 3000 In-stock
50 mg USD 4850 In-stock
100 mg USD 7800 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Selvigaltin Related Antibodies

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Description

Selvigaltin (GB1211) is an orally available galectin-3 (Gal-3) inhibitor[1].

IC50 & Target

Galectin-3

 

Clinical Trial
Molecular Weight

533.32

Formula

C19H16BrF3N4O4S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@@H]([C@H](O1)SC2=CN=CC(Br)=C2)[C@](N3C=C(C(C=C4F)=CC(F)=C4F)N=N3)([H])[C@H]([C@H]1CO)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 12.5 mg/mL (23.44 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8750 mL 9.3752 mL 18.7505 mL
5 mM 0.3750 mL 1.8750 mL 3.7501 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.72%

COA (250 KB) HNMR (302 KB) LCMS (94 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8750 mL 9.3752 mL 18.7505 mL 46.8762 mL
5 mM 0.3750 mL 1.8750 mL 3.7501 mL 9.3752 mL
10 mM 0.1875 mL 0.9375 mL 1.8750 mL 4.6876 mL
15 mM 0.1250 mL 0.6250 mL 1.2500 mL 3.1251 mL
20 mM 0.0938 mL 0.4688 mL 0.9375 mL 2.3438 mL
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Selvigaltin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Selvigaltin1978336-95-6GB1211GB 1211GB-1211Galectinorally availablefibrotic diseaseInhibitorinhibitorinhibit

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