2. Search Result
Search Result
Results for "

HIV+inhibitor

" in MedChemExpress (MCE) Product Catalog:

20

Inhibitors & Agonists

4

Natural
Products

3

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-158128
    MK-8527

    		HIV Reverse Transcriptase Infection
    MK-8527 is an orally active HIV inhibitor and nucleoside reverse transcriptase translocation inhibitor (NRTTI) with antiviral activity. MK-8527 has a similar inhibitory mechanism to ISL (HY-104012) .
    MK-8527
  • HY-16776
    Censavudine

    Festinavir; BMS-986001; OBP-601

    		 HIV Reverse Transcriptase Nucleoside Antimetabolite/Analog Infection
    Censavudine (OBP-601; BMS-986001), a nucleoside analog, is a nucleoside reverse transcriptase inhibitor. Censavudine is a potent HIV inhibitor with EC50 ranges from 30 nM to 81 nM and 450 nM to 890 nM for HIV-2 and HIV-1, respectively . Censavudine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Censavudine
  • HY-W279260
    APOBEC3G-IN-1

    		HIV Infection
    APOBEC3G-IN-1 (MN136.0154) is a potent HIV inhibitor, targeting APOBEC3G .
    APOBEC3G-IN-1
  • HY-137242
    Ingenol-3-palmitate

    		HIV Infection
    Ingenol-3-palmitate, an ingenane diterpenoid, is a nature product that could be isolated from the roots of Euphorbia ebracteolata. Ingenol-3-palmitate is a potent HIV-1 (HIV) inhibitor with an IC50 value of 4.1 nM .
    Ingenol-3-palmitate
  • HY-148202
    Influenza antiviral conjugate-1

    		HIV Infection
    Influenza antiviral conjugate-1 (INT-2) is a HIV inhibitor, shows potent cell fusion inhibition . Influenza antiviral conjugate-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Influenza antiviral conjugate-1
  • HY-121291
    Aureothin

    		HIV Infection
    Aureothin, is a natural polyketide, is a HIV inhibitor with an IC50 of 5.3 nM. Aureothin is a microbial biolarvicide .
    Aureothin
  • HY-16776A
    (2S,5S)-Censavudine

    (2S,5S)-Festinavir; (2S,5S)-BMS-986001; (2S,5S)-OBP-601

    		 HIV Infection
    (2S,5S)-Censavudine ((2S,5S)-OBP-601) is the (2S,5S)-enantiomer of Censavudine. Censavudine, a nucleoside reverse transcriptase inhibitor, is a potent HIV inhibitor . (2S,5S)-Censavudine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    (2S,5S)-Censavudine
  • HY-108255
    HIV-1 inhibitor-60

    		HIV Infection
    HIV-1 inhibitor-60 (compound 45) is an HIV inhibitor with the potential for the research of infection diseases .
    HIV-1 inhibitor-60
  • HY-127135
    B07

    		HIV Infection
    B07 is a HIV inhibitor. B07 also has spermicides activity (EC50: 1.5 mg/mL) .
    B07
  • HY-N12082
    HIV-IN-8

    		HIV Infection
    HIV-IN-8 (Compound 9) is a HIV inhibitor. HIV-IN-8 inhibits HIV replication with an EC50 of 13 μg/mL .
    HIV-IN-8
  • HY-N14095
    Curromycin A

    		Bacterial HIV Infection Cancer
    Curromycin A has antibacterial activity against Gram-positive bacteria such as Bacillus subtilis. Curromycin A can inhibit the replication of human immunodeficiency virus (HIV), inhibit mouse melanoma B16 and leukemia P388 cells .
    Curromycin A
  • HY-N14110
    Curromycin B

    		Bacterial HIV Infection
    Curromycin B has antibacterial activity against Gram-positive bacteria such as Bacillus subtilis. Curromycin B can inhibit the replication of human immunodeficiency virus (HIV), inhibit mouse melanoma B16 and leukemia P388 cells .
    Curromycin B
  • HY-117105
    DAPD-NHc-pr

    		HIV Infection
    DAPD-NHc-pr (compound 12) is an HIV inhibitor with EC50/EC90 values of 0.85 μM and 13 μM, respectively. DAPD-NHc-pr shows no toxicity to normal cells (PBM, CEM, VERO) .
    DAPD-NHc-pr
  • HY-156330
    HIV-IN-9

    		HIV Cytochrome P450 Infection
    HIV-IN-9 (Compound 2b) is a HIV inhibitor (IC50: 6.65 μg/mL), and has high binding affinity with HIV-RT. HIV-IN-9 also inhibits CYP3A4, CYP1A2, CYP2C1, and CYP2D6 .
    HIV-IN-9
  • HY-119120
    JTK-101

    		HIV CDK Infection Inflammation/Immunology
    JTK-101 is a selective HIV inhibitor. JTK-101 selectively reduces HIV-1 mRNA synthesis by inhibiting Tat cofactors, including CDK9 and cyclin T1, thereby suppressing the transcriptional activity of HIV-1. JTK-101 may be used in the field of anti-HIV virus research .
    JTK-101
  • HY-178985
    HIV-1-IN-90

    		HIV Infection
    HIV-1-IN-90 is a potent HIV inhibitor. HIV-1-IN-90 exhibits potent inhibitory activity against multiple drug-resistant HIV-1 strains with EC50s of 1.5-31 nM. HIV-1-IN-90 has good security. HIV-1-IN-90 can be used for research on HIV virus infection .
    HIV-1-IN-90
  • HY-149350
    HIV-1 inhibitor-57

    		HIV Infection
    HIV-1 inhibitor-57 (Compound 12g) is a HIV inhibitor. HIV-1 inhibitor-57 is active against wild-type and five prevalent NNRTI-resistant HIV-1 strains with EC50 values ranging from 0.024 to 0.0010 μM. HIV-1 inhibitor-57 forms additional interactions with residues around the binding site in HIV-1 RT .
    HIV-1 inhibitor-57
  • HY-169920
    HIV-1 inhibitor-79

    		HIV Reverse Transcriptase Infection
    HIV-1 inhibitor-79 (Compound 3k) is an HIV inhibitor that exhibits significant inhibitory activity against HIV-1 and its common mutant strains (with IC50 values of 1.9, 1.9, 8.7, and 11 nM against HIV-1, K103, L100I, and E138K, respectively), and has low cytotoxicity and a high selectivity index (CC50 = 21.95 μM, SI = 11478). Additionally, HIV-1 inhibitor-79 also shows antiviral activity against HIV-2, with an EC50 value of 6.14 μM, and significantly inhibits the activity of HIV-1 reverse transcriptase (IC50 = 25 nM) .
    HIV-1 inhibitor-79
  • HY-180543
    HIV-IN-13 prodrug

    		HIV Infection
    HIV-IN-13 prodrug (Compound 8) is a prodrug of an HIV inhibitor. Without the addition of glutathione (GSH), the HIV-IN-13 prodrug has no antiviral activity, but when 1 mM and 2 mM GSH are added, the EC50 values for HIV-1 are 10 μM and 8.2 μM respectively. HIV-IN-13 prodrug can be used in HIV infection research .
    HIV-IN-13 prodrug
  • HY-180566
    HIV-IN-13

    		HIV Infection
    HIV-IN-13 (compound 7) is a potent HIV inhibitor with low cellular toxicity. HIV-IN-13 inhibits HIV in CEM-SS cells with an EC50 of 1.38 μM. HIV-IN-13 displays antiviral activity in hPBMCs infected with different HIV strains (EC50 = 2.01-10.7 μM), while showing low cellular toxicity (TC50 >100 μM). HIV-IN-13 can be used for HIV-infection research .
    HIV-IN-13

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: