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Cat. No.: HY-117105

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DAPD-NHc-pr

DAPD-NHc-pr (compound 12) is an HIV inhibitor with EC₅₀/EC90 values of 0.85 μM and 13 μM, respectively. DAPD-NHc-pr shows no toxicity to normal cells (PBM, CEM, VERO).

For research use only. We do not sell to patients.

CAS No.: 280138-71-8
Formula: C₁₂H₁₆N₆O₃
Molecular Weight:292.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

DAPD-NHc-pr Chemical Structure

CAS No.: 280138-71-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

DAPD-NHc-pr (compound 12) is an HIV inhibitor with EC₅₀/EC90 values of 0.85 μM and 13 μM, respectively. DAPD-NHc-pr shows no toxicity to normal cells (PBM, CEM, VERO)^[1].

IC₅₀ & Target

EC50: 0.85 μM (HIV)^[1]

All HIV Isoforms :

Chemical Information

CAS No. 280138-71-8
Molecular Weight 292.29
Formula C₁₂H₁₆N₆O₃
SMILES

NC1=NC(NC2CC2)=C3N=CN([C@@H]4O[C@H](CO)OC4)C3=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Narayanasamy J, et al. Synthesis and anti-HIV activity of (-)-beta-D-(2R,4R)-1,3-dioxolane-2,6-diamino purine (DAPD) (amdoxovir) and (-)-beta-D-(2R,4R)-1,3-dioxolane guanosine (DXG) prodrugs. Antiviral Res. 2007 Sep;75(3):198-209. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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DAPD-NHc-pr

All HIV Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

DAPD-NHc-pr Related Classifications

HY-117105 Related Classifications