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  3. HIV
  4. HIV-IN-13 prodrug

HIV-IN-13 prodrug (Compound 8) is a prodrug of an HIV inhibitor. Without the addition of glutathione (GSH), the HIV-IN-13 prodrug has no antiviral activity, but when 1 mM and 2 mM GSH are added, the EC50 values for HIV-1 are 10 μM and 8.2 μM respectively. HIV-IN-13 prodrug can be used in HIV infection research.

For research use only. We do not sell to patients.

HIV-IN-13 prodrug

HIV-IN-13 prodrug Chemical Structure

CAS No. : 3049284-12-7

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HIV-IN-13 prodrug Related Antibodies

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Description

HIV-IN-13 prodrug (Compound 8) is a prodrug of an HIV inhibitor. Without the addition of glutathione (GSH), the HIV-IN-13 prodrug has no antiviral activity, but when 1 mM and 2 mM GSH are added, the EC50 values for HIV-1 are 10 μM and 8.2 μM respectively. HIV-IN-13 prodrug can be used in HIV infection research[1].

Molecular Weight

677.63

Formula

C31H25F2N7O7S
CAS No.
SMILES

FC1(F)OC(C=C(C2=C3)N(C=C(C2=O)C(NCC4=NC(C)=CC=C4)=O)CCNC(C5=C(C=CC=C5)SC6=C(N=CN6C)[N+]([O-])=O)=O)=C3O1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HIV-IN-13 prodrug Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HIV-IN-13 prodrug3049284-12-7HIVHuman immunodeficiency virusHIV-1 inhibitorsNCp7 targeting agentsprodrug designnitroimidazole derivativespharmacokineticsmetabolic stabilitystructure-activity relationshipInhibitorinhibitorinhibit

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