2. Anti-infection
  3. HIV
  4. HIV-IN-13 prodrug

HIV-IN-13 prodrug (Compound 8) is a prodrug of an HIV inhibitor. Without the addition of glutathione (GSH), the HIV-IN-13 prodrug has no antiviral activity, but when 1 mM and 2 mM GSH are added, the EC50 values for HIV-1 are 10 μM and 8.2 μM respectively. HIV-IN-13 prodrug can be used in HIV infection research.

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HIV-IN-13 prodrug

HIV-IN-13 prodrug Estructura química

No. CAS : 3049284-12-7

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HIV-IN-13 prodrug Related Antibodies

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Descripciòn

HIV-IN-13 prodrug (Compound 8) is a prodrug of an HIV inhibitor. Without the addition of glutathione (GSH), the HIV-IN-13 prodrug has no antiviral activity, but when 1 mM and 2 mM GSH are added, the EC50 values for HIV-1 are 10 μM and 8.2 μM respectively. HIV-IN-13 prodrug can be used in HIV infection research[1].

Peso molecular

677.63

Fòrmula

C31H25F2N7O7S
No. CAS
SMILES

FC1(F)OC(C=C(C2=C3)N(C=C(C2=O)C(NCC4=NC(C)=CC=C4)=O)CCNC(C5=C(C=CC=C5)SC6=C(N=CN6C)[N+]([O-])=O)=O)=C3O1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
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Referencias
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HIV-IN-13 prodrug Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HIV-IN-13 prodrug3049284-12-7HIVHuman immunodeficiency virusHIV-1 inhibitorsNCp7 targeting agentsprodrug designnitroimidazole derivativespharmacokineticsmetabolic stabilitystructure-activity relationshipInhibitorinhibitorinhibit

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Nombre del producto:
HIV-IN-13 prodrug
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HY-180543
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