3049284-12-7
3049284-12-7
Chemical Structure
HIV-IN-13 prodrug
- CAS No.: 3049284-12-7
- Formula:C31H25F2N7O7S
- Molecular Weight:677.63
InChIKey: ZDCCUSZBYLUECY-UHFFFAOYSA-N
SMILES: FC1(F)OC(C=C(C2=C3)N(C=C(C2=O)C(NCC4=NC(C)=CC=C4)=O)CCNC(C5=C(C=CC=C5)SC6=C(N=CN6C)[N+]([O-])=O)=O)=C3O1
Biological Activity: HIV-IN-13 prodrug (Compound 8) is a prodrug of an HIV inhibitor. Without the addition of glutathione (GSH), the HIV-IN-13 prodrug has no antiviral activity, but when 1 mM and 2 mM GSH are added, the EC50 values for HIV-1 are 10 μM and 8.2 μM respectively. HIV-IN-13 prodrug can be used in HIV infection research[1].
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HIV-IN-13 prodrug | HIV-IN-13 prodrug (Compound 8) is a prodrug of an HIV inhibitor. Without the addition of glutathione (GSH), the HIV-IN-13 prodrug has no antiviral activity, but when 1 mM and 2 mM GSH are added, the EC50 values for HIV-1 are 10 μM and 8.2 μM respectively. HIV-IN-13 prodrug can be used in HIV infection research. | |||||||||||||||||||||
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