HIV-1 inhibitor-57
HIV-1 inhibitor-57 (Compound 12g) is a HIV inhibitor. HIV-1 inhibitor-57 is active against wild-type and five prevalent NNRTI-resistant HIV-1 strains with EC50 values ranging from 0.024 to 0.0010 μM. HIV-1 inhibitor-57 forms additional interactions with residues around the binding site in HIV-1 RT.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2745197-24-2
- Fòrmula: C25H24FN5O3S
- Peso molecular:493.55
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | CC50 |
15.75 μM
Compound: 12g
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Cytotoxicity against human MT4 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human MT4 cells assessed as reduction in cell viability by MTT assay
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[PMID: 37393790] |
Chemical Information
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No. CAS 2745197-24-2
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Peso molecular 493.55
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Fòrmula C25H24FN5O3S
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SMILES
CC1=C(OC2=CC=NC(NC3=CC(F)=C(N4CCS(CC4)(=O)=O)C=C3)=N2)C(C)=CC(/C=C/C#N)=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HIV-1 inhibitor-57 Related Classifications
HY-149350 Related Classifications
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