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Results for "

Ishikawa

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

5

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16441
    Tegafur-gimeracil-oteracil potassium

    S-1; TS-1

    		 PI3K Akt mTOR Apoptosis Bcl-2 Family Cancer
    Tegafur-gimeracil-oteracil potassium (S-1; TS-1) is an orally active anticancer agent composed of Tegafur (HY-17400), Gimeracil (HY-17469), and Oteracil potassium (HY-17511). Tegafur-gimeracil-oteracil potassium inhibits the proliferation, migration and invasion of endometrial cancer cells and induces apoptosis by blocking the PI3K/AKT/mTOR signaling pathway. Tegafur-gimeracil-oteracil potassium can be used in research related to endometrial cancer and gastric cancer with peritoneal metastasis .
    Tegafur-gimeracil-oteracil potassium
  • HY-N4012
    Indole-3-glyoxylamide

    3-Indoleglyoxamide

    		 Others Others
    Indole-3-glyoxylamide (Compound 4) is a type of indole alkaloid. Indole-3-glyoxylamide shows no significant cytotoxic activity against Hela, Ishikawa, and MGC-803 cells .
    Indole-3-glyoxylamide
  • HY-151477
    SARS-CoV-2-IN-32

    		SARS-CoV Infection Cancer
    SARS-CoV-2-IN-32 (compound 3g) is a COVID-19 inhibitor. SARS-CoV-2-IN-32 shows anti-proliferative activity against cancer cells. SARS-CoV-2-IN-32 exhibits comparatively high binding affinity (-8.8 Kcal/mole) to COVID-19 main protease (M pro) (PDB ID: 6LU7). SARS-CoV-2-IN-32 can be used in studies of cancer and COVID-19 .
    SARS-CoV-2-IN-32
  • HY-N12044
    Asparanin A

    		Apoptosis Cancer
    Asparanin A is an apoptosis inducer with anticancer activity. Asparanin A induces cell cycle arrest in the G0/G1 phase through mitochondria and PI3K/AKT signaling pathways, inhibiting cancer cell growth. Asparanin A also demonstrated in vivo efficacy in a mouse xenograft model of Ishikawa endometrial carcinoma, significantly inhibiting tumor growth .
    Asparanin A
  • HY-151478
    SARS-CoV-2-IN-33

    		SARS-CoV Infection Cancer
    SARS-CoV-2-IN-33 (compound 3m) is a COVID-19 inhibitor. SARS-CoV-2-IN-33 shows anti-proliferative activity against cancer cells. SARS-CoV-2-IN-33 exhibits comparatively good binding affinity (-8.0 Kcal/mole) to COVID-19 main protease (M pro) (PDB ID: 6LU7). SARS-CoV-2-IN-33 can be used in studies of cancer and COVID-19 .
    SARS-CoV-2-IN-33
  • HY-N7825
    Gomisin L1

    		Others Cancer
    Gomisin L1 is a lignan, shows inhibitory effect on cell viability of A2780 and Ishikawa cells, with IC50s of 39.06 μM and 74.16 μM, respectively .
    Gomisin L1
  • HY-N2852
    α-Terthienylmethanol

    		Reactive Oxygen Species (ROS) Others
    α-Terthienylmethanol is a terthiophene isolated from the n-hexane fraction of E. prostrata. α-Terthienylmethanol has potent cytotoxic activity against human endometrial cancer cells (Hec1A and Ishikawa) (IC50 < 1 μM). α-Terthienylmethanol increases the intracellular level of ROS and decreases that of GSH .
    α-Terthienylmethanol
  • HY-151474
    SARS-CoV-2-IN-31

    		SARS-CoV Cancer
    SARS-CoV-2-IN-31 is an effective COVID-19 inhibitor. SARS-CoV-2-IN-31 exhibits excellent to mild activity against various cancer cell lines with IC50 values range from 28.84 to 38.36 μM. SARS-CoV-2-IN-31 can be used for the research of cancer .
    SARS-CoV-2-IN-31
  • HY-N13845
    2'-Prenylisorhamnetin

    		Drug Derivative Others
    2'-Prenylisorhamnetin is a natural flavonoid.
    2'-Prenylisorhamnetin
  • HY-181637
    4-DMA-3'-OH-Chalcone

    		Drug Derivative Endocrinology
    4-DMA-3'-OH-Chalcone (compound 24) is a synthetic chalcone derivative and selective cytotoxic agent.4-DMA-3'-OH-Chalcone reduces viability of endometriotic cells, while preserving or enhancing viability of eutopic endometrial cells.4-DMA-3'-OH-Chalcone can be used for the research of endometriosis .
    4-DMA-3'-OH-Chalcone
  • HY-181638
    4-Cl-Benzodioxolyl chalcone

    		Drug Derivative Metabolic Disease
    4-Cl-Benzodioxolyl chalcone is a type of chalcone. It reduces the viability of endometriotic cells while maintaining or increasing the viability of normal endometrial cells. 4-Cl-Benzodioxolyl chalcone can be used in the research of endometriosis .
    4-Cl-Benzodioxolyl chalcone

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