4-Cl-Benzodioxolyl chalcone
4-Cl-Benzodioxolyl chalcone is a type of chalcone. It reduces the viability of endometriotic cells while maintaining or increasing the viability of normal endometrial cells. 4-Cl-Benzodioxolyl chalcone can be used in the research of endometriosis.
For research use only. We do not sell to patients.
- CAS No.: 934022-22-7
- Formula: C16H11ClO3
- Molecular Weight:286.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| L929 | CC50 |
200 μM
Compound: 3
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Cytotoxicity in mouse NCTC-929 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity in mouse NCTC-929 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
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[PMID: 31000155] |
4-Cl-Benzodioxolyl chalcone (Compound 28) (200 μM; 24 h) selectively reduces the viability of ectopic endometrial cells to 53.18%, while increases the viability of eutopic endometrial cells to 114.67%, exhibiting selective cytotoxicity profiles favorable for targeting endometriosis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Ishikawa eutopic endometrial cells, 12Z endometriotic cells
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Concentration:200 μM
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Incubation Time:24 h
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Result:Increased Ishikawa eutopic endometrial cell viability to 114.67% relative to untreated cells.
Reduced 12Z endometriotic cell viability to 53.18% relative to untreated cells.
Exhibited a 61.49% viability difference between the two cell lines with statistically significant selectivity.
Chemical Information
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CAS No. 934022-22-7
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Molecular Weight 286.71
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Formula C16H11ClO3
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SMILES
O=C(C1=CC=C(Cl)C=C1)/C=C/C2=CC=C(OCO3)C3=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Cl-Benzodioxolyl chalcone Related Classifications
HY-181638 Related Classifications
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