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  3. Drug Derivative
  4. 4-Cl-Benzodioxolyl chalcone

4-Cl-Benzodioxolyl chalcone is a type of chalcone. It reduces the viability of endometriotic cells while maintaining or increasing the viability of normal endometrial cells. 4-Cl-Benzodioxolyl chalcone can be used in the research of endometriosis.

For research use only. We do not sell to patients.

4-Cl-Benzodioxolyl chalcone

4-Cl-Benzodioxolyl chalcone Chemical Structure

CAS No. : 934022-22-7

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4-Cl-Benzodioxolyl chalcone Related Antibodies

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Description

4-Cl-Benzodioxolyl chalcone is a type of chalcone. It reduces the viability of endometriotic cells while maintaining or increasing the viability of normal endometrial cells. 4-Cl-Benzodioxolyl chalcone can be used in the research of endometriosis[1].

In Vitro

4-Cl-Benzodioxolyl chalcone (Compound 28) (200 μM; 24 h) selectively reduces the viability of ectopic endometrial cells to 53.18%, while increases the viability of eutopic endometrial cells to 114.67%, exhibiting selective cytotoxicity profiles favorable for targeting endometriosis[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

4-Cl-Benzodioxolyl chalcone Related Antibodies

Cell Viability Assay[1]

Cell Line: Ishikawa eutopic endometrial cells, 12Z endometriotic cells
Concentration: 200 μM
Incubation Time: 24 h
Result: Increased Ishikawa eutopic endometrial cell viability to 114.67% relative to untreated cells.
Reduced 12Z endometriotic cell viability to 53.18% relative to untreated cells.
Exhibited a 61.49% viability difference between the two cell lines with statistically significant selectivity.
Molecular Weight

286.71

Formula

C16H11ClO3
CAS No.
SMILES

O=C(C1=CC=C(Cl)C=C1)/C=C/C2=CC=C(OCO3)C3=C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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4-Cl-Benzodioxolyl chalcone Related Classifications

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  • Do most proteins show cross-species activity?

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Keywords:

4-Cl-Benzodioxolyl chalcone934022-22-7Drug DerivativeDrug derivativeflavonoid derivativenormal endometrial cellsendometriotic cells12Z endometriotic cellIshikawa eutopic endometrial cellchalconeendometriosisInhibitorinhibitorinhibit

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4-Cl-Benzodioxolyl chalcone
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