SARS-CoV-2-IN-33
Based on 1 Customer Validation
SARS-CoV-2-IN-33 (compound 3m) is a COVID-19 inhibitor. SARS-CoV-2-IN-33 shows anti-proliferative activity against cancer cells. SARS-CoV-2-IN-33 exhibits comparatively good binding affinity (-8.0 Kcal/mole) to COVID-19 main protease (Mpro) (PDB ID: 6LU7). SARS-CoV-2-IN-33 can be used in studies of cancer and COVID-19.
For research use only. We do not sell to patients.
- Purity: 99.02%
- CAS No.: 299919-79-2
- Formula: C30H30N4O5
- Molecular Weight:526.58
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Anti-Infection Compound Library
HY-L002
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Anti-Cancer Compound Library
HY-L025
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Antiviral Compound Library
HY-L027
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Heterocyclic Compound Library
HY-L138
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MCE Bioactive Compound Library
HY-L001V
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High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
COVID-19[1].
SARS-CoV-2-IN-33 (0-40 µM) exhibits good antiproliferative activity in MCF-7, MDA-MB-231, HeLa and PC-3 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MCF-7, MDA-MB-231, HeLa, PC-3, Ishikawa, HEK-293
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Concentration:0-40 µM
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Incubation Time:48 h
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Result:Inhibited proliferation of MCF-7, MDA-MB-231, HeLa, PC-3, Ishikawa, HEK-293 cells with IC50 values of 5.45, 9.47, 22.86, 28.44, >40 and >40 μM, respectively.
Chemical Information
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CAS No. 299919-79-2
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Appearance Solid
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Molecular Weight 526.58
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Formula C30H30N4O5
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Color White to off-white
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SMILES
OC1=C(C(C2=C(N(C3=CC=CC=C3)N=C2C)O)C4=CC(OC)=C(C(OC)=C4)OC)C(C)=NN1C5=CC=CC=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (94.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (280 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8990 mL | 9.4952 mL | 18.9905 mL | 47.4762 mL |
| 5 mM | 0.3798 mL | 1.8990 mL | 3.7981 mL | 9.4952 mL | |
| 10 mM | 0.1899 mL | 0.9495 mL | 1.8990 mL | 4.7476 mL | |
| 15 mM | 0.1266 mL | 0.6330 mL | 1.2660 mL | 3.1651 mL | |
| 20 mM | 0.0950 mL | 0.4748 mL | 0.9495 mL | 2.3738 mL | |
| 25 mM | 0.0760 mL | 0.3798 mL | 0.7596 mL | 1.8990 mL | |
| 30 mM | 0.0633 mL | 0.3165 mL | 0.6330 mL | 1.5825 mL | |
| 40 mM | 0.0475 mL | 0.2374 mL | 0.4748 mL | 1.1869 mL | |
| 50 mM | 0.0380 mL | 0.1899 mL | 0.3798 mL | 0.9495 mL | |
| 60 mM | 0.0317 mL | 0.1583 mL | 0.3165 mL | 0.7913 mL | |
| 80 mM | 0.0237 mL | 0.1187 mL | 0.2374 mL | 0.5935 mL |
SARS-CoV-2-IN-33 Related Classifications
HY-151478 Related Classifications
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