2. Anti-infection
  3. SARS-CoV
  4. SARS-CoV-2-IN-31

SARS-CoV-2-IN-31 is an effective COVID-19 inhibitor. SARS-CoV-2-IN-31 exhibits excellent to mild activity against various cancer cell lines with IC50 values range from 28.84 to 38.36 μM. SARS-CoV-2-IN-31 can be used for the research of cancer.

For research use only. We do not sell to patients.

SARS-CoV-2-IN-31

SARS-CoV-2-IN-31 Chemical Structure

CAS No. : 1017691-52-9

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
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SARS-CoV-2-IN-31 Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

SARS-CoV-2-IN-31 is an effective COVID-19 inhibitor. SARS-CoV-2-IN-31 exhibits excellent to mild activity against various cancer cell lines with IC50 values range from 28.84 to 38.36 μM. SARS-CoV-2-IN-31 can be used for the research of cancer[1].

IC50 & Target

IC50: 38.36 μM (MCF-7); 38.46 μM (MDA-MB-231); 28.84 μM (HeLa); 30.62 μM (PC-3); ＞40 μM (Ishikawa)[1]
In Vitro

SARS-CoV-2-IN-31 exhibits antiproliferative activity in five different human cancer cell lines with IC50 values of 38.36 μM (MCF-7), 38.46 μM (MDA-MB-231), 28.84 μM (HeLa), 30.62 μM (PC-3) and ＞40 μM (Ishikawa), respectively[1].
SARS-CoV-2-IN-31 shows comparatively high binding affinity with value of -8.3 Kcal/mole[1]

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SARS-CoV-2-IN-31 Related Antibodies
Molecular Weight

464.56

Formula

C29H28N4O2
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

OC1=C(C(C2=C(N(C3=CC=CC=C3)N=C2C)O)C4=CC=C(CC)C=C4)C(C)=NN1C5=CC=CC=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (107.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1526 mL 10.7629 mL 21.5257 mL
5 mM 0.4305 mL 2.1526 mL 4.3051 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1526 mL 10.7629 mL 21.5257 mL 53.8144 mL
5 mM 0.4305 mL 2.1526 mL 4.3051 mL 10.7629 mL
10 mM 0.2153 mL 1.0763 mL 2.1526 mL 5.3814 mL
15 mM 0.1435 mL 0.7175 mL 1.4350 mL 3.5876 mL
20 mM 0.1076 mL 0.5381 mL 1.0763 mL 2.6907 mL
25 mM 0.0861 mL 0.4305 mL 0.8610 mL 2.1526 mL
30 mM 0.0718 mL 0.3588 mL 0.7175 mL 1.7938 mL
40 mM 0.0538 mL 0.2691 mL 0.5381 mL 1.3454 mL
50 mM 0.0431 mL 0.2153 mL 0.4305 mL 1.0763 mL
60 mM 0.0359 mL 0.1794 mL 0.3588 mL 0.8969 mL
80 mM 0.0269 mL 0.1345 mL 0.2691 mL 0.6727 mL
100 mM 0.0215 mL 0.1076 mL 0.2153 mL 0.5381 mL
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SARS-CoV-2-IN-31 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SARS-CoV-2-IN-311017691-52-9SARS-CoVSARS coronavirusCOVID-19MCF-7cellsMDA-MB-231cellsHeLa cellsPC-3 cellsIshikawa cellscancerInhibitorinhibitorinhibit

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