2. Others
  3. Drug Derivative
  4. 4-DMA-3'-OH-Chalcone

4-DMA-3'-OH-Chalcone (compound 24) is a synthetic chalcone derivative and selective cytotoxic agent.4-DMA-3'-OH-Chalcone reduces viability of endometriotic cells, while preserving or enhancing viability of eutopic endometrial cells.4-DMA-3'-OH-Chalcone can be used for the research of endometriosis.

For research use only. We do not sell to patients.

4-DMA-3'-OH-Chalcone

4-DMA-3'-OH-Chalcone Chemical Structure

CAS No. : 946437-21-4

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

4-DMA-3'-OH-Chalcone Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

4-DMA-3'-OH-Chalcone (compound 24) is a synthetic chalcone derivative and selective cytotoxic agent.4-DMA-3'-OH-Chalcone reduces viability of endometriotic cells, while preserving or enhancing viability of eutopic endometrial cells.4-DMA-3'-OH-Chalcone can be used for the research of endometriosis[1].

In Vitro

4-DMA-3'-OH-Chalcone (compound 24) (200 μM; 24 h) selectively reduces 12Z endometriotic cell viability to 48.65% while increasing Ishikawa eutopic endometrial cell viability to 109.23%[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

4-DMA-3'-OH-Chalcone Related Antibodies

Cell Viability Assay[1]

Cell Line: Ishikawa (eutopic endometrial) epithelial cell line, 12Z (endometriotic) epithelial cell line
Concentration: 200 μM
Incubation Time: 24 h
Result: Increased Ishikawa cell viability to 109.23% relative to untreated control cells.
Reduced 12Z cell viability to 48.65% relative to untreated control cells.
Induced a statistically significant 60.58 percentage point difference in viability between the two cell lines.
Molecular Weight

267.32

Formula

C17H17NO2
CAS No.
SMILES

O=C(C1=CC=CC(O)=C1)/C=C/C2=CC=C(N(C)C)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

4-DMA-3'-OH-Chalcone Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-DMA-3'-OH-Chalcone946437-21-4Drug DerivativeDrug derivativeIshikawa eutopic endometrial cell12Z endometriotic celleutopic endometrial cellsendometriosisendometriotic cellsInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
4-DMA-3'-OH-Chalcone
Cat. No.:
HY-181637
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.