LIF

By Targets:	Apoptosis (1) Fluorescent Dye (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (4)
Click Chemistry:	Alkynes (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0974

Sulforhodamine B sodium salt 1 Publications Verification Acid Red 52; Kiton Red 620	Fluorescent Dye	Others
Sulforhodamine B sodium salt is a fluorescent dye with uses spanning from laser-induced fluorescence (LIF) to the quantification of cellular proteins of cultured cells.

HY-120142

EC359 5+ Cited Publications	Apoptosis	Cancer
EC359 is a potent, selective, high affinity and orally active leukemia inhibitory factor receptor (LIFR) inhibitor with a K_d of 10.2 nM, which directly interacts with LIFR to effectively block LIF/LIFR interactions . EC359 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-RS07640

LIF Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
LIF Human Pre-designed siRNA Set A contains three designed siRNAs for LIF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

LIF Human Pre-designed siRNA Set A LIF Human Pre-designed siRNA Set A

Cat. No.	Product Name	Type

HY-D0974

Sulforhodamine B sodium salt 1 Publications Verification Acid Red 52; Kiton Red 620	Dyes
Sulforhodamine B sodium salt is a fluorescent dye with uses spanning from laser-induced fluorescence (LIF) to the quantification of cellular proteins of cultured cells.

Cat. No.	Product Name	Target	Research Area

HY-P4066

Emfilermin

Peptides Cancer

Emfilermin is a recombinant human leukaemia inhibitory factor (LIF) that can be used in chemotherapy-induced peripheral neuropathy studies .

Emfilermin	Peptides	Cancer
Emfilermin is a recombinant human leukaemia inhibitory factor (LIF) that can be used in chemotherapy-induced peripheral neuropathy studies .

Cat. No.	Product Name	Target	Research Area

HY-P990039

Falbikitug

Inhibitory Antibodies Cancer

Falbikitug is a humanized immunoglobulin G1-kappa, anti-LIF monoclonal antibody. Falbikitug is an antineoplastic .

Falbikitug	Inhibitory Antibodies	Cancer
Falbikitug is a humanized immunoglobulin G1-kappa, *anti-LIF* monoclonal antibody. Falbikitug is an antineoplastic .

Species:	Human (10) Mouse (6) Rat (2)
Tag:	His (9) Tag Free (5) Fc (4) Flag (1)
Source:	HEK293 (14) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source

HY-P73276

	LIF Protein, Human (HEK293) LIF; Leukemia inhibitory factor; HILDA; D factor; MLPLI	Human	HEK293
	LIF protein induces terminal differentiation in leukemic cells, promoting hematopoietic and neuronal cell differentiation, and stimulating acute-phase protein synthesis in hepatocytes. Its diverse activities highlight its role in influencing cellular differentiation across various cell types and physiological contexts. LIF Protein, Human (HEK293) is the recombinant human-derived LIF protein, expressed by HEK293 , with tag free. The total length of LIF Protein, Human (HEK293) is 180 a.a., with molecular weight of 34-55 kDa.

HY-P73279

	LIF Protein, Mouse (HEK293) LIF; Leukemia inhibitory factor; HILDA; D factor; MLPLI	Mouse	HEK293
	LIF (Leukemia Inhibitory Factor) prompts terminal differentiation in leukemic cells, inducing hematopoietic and neuronal cell differentiation. It also stimulates acute-phase protein synthesis in hepatocytes. LIF's multifaceted role underscores its significance in regulating hematopoiesis, neurogenesis, and hepatic responses. LIF Protein, Mouse (HEK293) is the recombinant mouse-derived LIF protein, expressed by HEK293 , with tag free. The total length of LIF Protein, Mouse (HEK293) is 180 a.a., with molecular weight of ~35.6 kDa.

HY-P73277

	LIF Protein, Human (HEK293, Fc) LIF; Leukemia inhibitory factor; HILDA; D factor; MLPLI	Human	HEK293
	LIF protein induces terminal differentiation in leukemic cells, promoting hematopoietic and neuronal cell differentiation, and stimulating acute-phase protein synthesis in hepatocytes. Its diverse activities highlight its role in influencing cellular differentiation across various cell types and physiological contexts. LIF Protein, Human (HEK293, Fc) is the recombinant human-derived LIF protein, expressed by HEK293 , with C-hFc labeled tag. The total length of LIF Protein, Human (HEK293, Fc) is 202 a.a., with molecular weight of ~63 kDa.

HY-P73278

	LIF Protein, Human (HEK293, His) LIF; Leukemia inhibitory factor; HILDA; D factor; MLPLI	Human	HEK293
	LIF protein induces terminal differentiation in leukemic cells, promoting hematopoietic and neuronal cell differentiation, and stimulating acute-phase protein synthesis in hepatocytes. Its diverse activities highlight its role in influencing cellular differentiation across various cell types and physiological contexts. LIF Protein, Human (HEK293, His) is the recombinant human-derived LIF protein, expressed by HEK293 , with C-His labeled tag. The total length of LIF Protein, Human (HEK293, His) is 202 a.a., with molecular weight of 35-42 kDa.

HY-P73280

	LIF Protein, Mouse (HEK293, His) LIF; Leukemia inhibitory factor; HILDA; D factor; MLPLI	Mouse	HEK293
	LIF (Leukemia Inhibitory Factor) prompts terminal differentiation in leukemic cells, inducing hematopoietic and neuronal cell differentiation. It also stimulates acute-phase protein synthesis in hepatocytes. LIF's multifaceted role underscores its significance in regulating hematopoiesis, neurogenesis, and hepatic responses. LIF Protein, Mouse (HEK293, His) is the recombinant mouse-derived LIF protein, expressed by HEK293 , with C-His labeled tag. The total length of LIF Protein, Mouse (HEK293, His) is 203 a.a., with molecular weight of 35-45 kDa.

HY-P7084

	LIF Protein, Mouse 3 Publications Verification rMuLIF; Differentiation-stimulating Factor; D factor; MLPLI	Mouse	E. coli
	LIF Protein, Mouse is a lymphoid factor involved in various neural and inflammatory processes such as the acute-phase reaction, tissue damage, and infection.

HY-P7049

	LIF Protein, Human rHuLIF; Differentiation-stimulating Factor; D factor; MLPLI	Human	E. coli
	LIF Protein, Human is a lymphoid factor involved in various neural and inflammatory processes such as the acute-phase reaction, tissue damage, and infection.

HY-P78324

	LIF Protein, Mouse (HEK293, Fc) LIF; HILDA; MLPLI; CDF; DIA	Mouse	HEK293
	LIF (Leukemia Inhibitory Factor) prompts terminal differentiation in leukemic cells, inducing hematopoietic and neuronal cell differentiation. It also stimulates acute-phase protein synthesis in hepatocytes. LIF's multifaceted role underscores its significance in regulating hematopoiesis, neurogenesis, and hepatic responses. LIF Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived LIF protein, expressed by HEK293 , with C-hFc labeled tag. The total length of LIF Protein, Mouse (HEK293, Fc) is 179 a.a., with molecular weight of 67-70 kDa.

HY-P78621

	LIF Protein, Rat (HEK293, His) LIF; CDF; DIA; HILDA; MLPLI	Rat	HEK293
	Lif Protein, a cytokine, plays a vital role in cell proliferation, differentiation, and immune response regulation. Dysregulation of Lif Protein has been linked to various diseases, including cancer and inflammatory disorders. Targeting Lif Protein may offer potential therapeutic interventions in these conditions by modulating cell growth, promoting immune regulation, and suppressing inflammation. LIF Protein, Rat (HEK293, His) is the recombinant rat-derived LIF protein, expressed by HEK293 , with C-6*His labeled tag. The total length of LIF Protein, Rat (HEK293, His) is 180 a.a., with molecular weight of 30-55 kDa.

HY-P73276A

	LIF Protein, Human (HEK293, solution) LIF; Leukemia inhibitory factor; HILDA; D factor; MLPLI	Human	HEK293
	LIF protein induces terminal differentiation in leukemic cells, promoting hematopoietic and neuronal cell differentiation, and stimulating acute-phase protein synthesis in hepatocytes. Its diverse activities highlight its role in influencing cellular differentiation across various cell types and physiological contexts. LIF Protein, Human (HEK293, solution) is the recombinant human-derived LIF protein, expressed by HEK293 , with tag free. The total length of LIF Protein, Human (HEK293, solution) is 202 a.a., with molecular weight of ~35.4 kDa.

HY-P75907

	LIFR Protein, Rat (HEK293, His) Leukemia inhibitory factor receptor; LIF-R; CD118	Rat	HEK293
	The LIFR Protein, a vital member of the type I cytokine receptor family, mediates cellular responses to various cytokines, emphasizing its role in cell differentiation and immune regulation. Its study provides insights into the unique contributions of LIFR within the type I cytokine receptor family, offering potential applications in therapeutic interventions for conditions related to cell differentiation and immune response modulation. Further exploration holds promise for enhancing our knowledge of LIFR's role in both normal cellular function and pathological conditions. LIFR Protein, Rat (HEK293, His) is the recombinant rat-derived LIFR protein, expressed by HEK293, with C-His labeled tag. The total length of LIFR Protein, Rat (HEK293, His) is 829 a.a., with molecular weight of ~116 kDa.

HY-P77058

	LIFR Protein, Human (HEK293, Fc) Leukemia inhibitory factor receptor; LIF-R; CD118	Human	HEK293
	LIFR Protein, a signal-transducing molecule, potentially shares a common pathway with IL6ST. Its soluble form inhibits LIF binding to target cell receptors, reducing biological activity. LIFR forms a heterodimer with IL6ST, interacting with the CNTF and CNTFR complex, implying potential crosstalk and collaborative actions in cellular processes. LIFR Protein, Human (HEK293, Fc) is the recombinant human-derived LIFR protein, expressed by HEK293 , with C-hFc labeled tag. The total length of LIFR Protein, Human (HEK293, Fc) is 833 a.a., with molecular weight of ~116.1 KDa.

HY-P77059

	LIFR Protein, Human (HEK293, His) Leukemia inhibitory factor receptor; LIF-R; CD118	Human	HEK293
	LIFR Protein, a signal-transducing molecule, potentially shares a common pathway with IL6ST. Its soluble form inhibits LIF binding to target cell receptors, reducing biological activity. LIFR forms a heterodimer with IL6ST, interacting with the CNTF and CNTFR complex, implying potential crosstalk and collaborative actions in cellular processes. LIFR Protein, Human (HEK293, His) is the recombinant human-derived LIFR protein, expressed by HEK293 , with C-His labeled tag. The total length of LIFR Protein, Human (HEK293, His) is 833 a.a., with molecular weight of 125-135 kDa.

HY-P77061

	LIFR Protein, Mouse (HEK293, His) Leukemia inhibitory factor receptor; LIF-R; CD118	Mouse	HEK293
	LIFR Protein, a signal-transducing molecule, may share a common pathway with IL6ST. Its soluble form acts as an inhibitor, blocking LIF binding to receptors and reducing biological activity. LIFR forms a heterodimer with IL6ST, interacting with the CNTF and CNTFR complex, indicating potential cross-talk and cooperative actions in cellular processes. LIFR Protein, Mouse (HEK293, His) is the recombinant mouse-derived LIFR protein, expressed by HEK293 , with C-His labeled tag. The total length of LIFR Protein, Mouse (HEK293, His) is 785 a.a., with molecular weight of 96-140 kDa.

HY-P700418

	LIFR Protein, Human (HEK293, hFc-Flag) LIFR; leukemia inhibitory factor receptor alpha; leukemia inhibitory factor receptor; CD118; LIF receptor; CD118 antigen; SWS; SJS2; STWS; LIF-R; FLJ98106; FLJ99923	Human	HEK293
	LIFR Protein, a signal-transducing molecule, potentially shares a common pathway with IL6ST. Its soluble form inhibits LIF binding to target cell receptors, reducing biological activity. LIFR forms a heterodimer with IL6ST, interacting with the CNTF and CNTFR complex, implying potential crosstalk and collaborative actions in cellular processes. LIFR Protein, Human (HEK293, hFc-Flag) is the recombinant human-derived LIFR protein, expressed by HEK293 , with C-hFc, C-Flag labeled tag. The total length of LIFR Protein, Human (HEK293, hFc-Flag) is 789 a.a., with molecular weight of 119.3 kDa.

HY-P77060

	LIFR Protein, Human (Biotinylated, HEK293, His) Leukemia inhibitory factor receptor; LIF-R; CD118	Human	HEK293
	LIFR Protein, a signal-transducing molecule, potentially shares a common pathway with IL6ST. Its soluble form inhibits LIF binding to target cell receptors, reducing biological activity. LIFR forms a heterodimer with IL6ST, interacting with the CNTF and CNTFR complex, implying potential crosstalk and collaborative actions in cellular processes. LIFR Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived LIFR protein, expressed by HEK293 , with C-His labeled tag. The total length of LIFR Protein, Human (Biotinylated, HEK293, His) is 833 a.a., with molecular weight of 125-135 kDa.

HY-P700135AF

	*Animal-Free LIF* Protein, Human (His)** Leukemia inhibitory factor; HILDA; D factor; MLPLI	Human	E. coli
	LIF protein induces terminal differentiation in leukemic cells, promoting hematopoietic and neuronal cell differentiation, and stimulating acute-phase protein synthesis in hepatocytes. Its diverse activities highlight its role in influencing cellular differentiation across various cell types and physiological contexts. Animal-Free LIF Protein, Human (His) is the recombinant human-derived animal-FreeLIF protein, expressed by E. coli , with N-His labeled tag. The total length of Animal-Free LIF Protein, Human (His) is 180 a.a., with molecular weight of ~20.52 kDa.

HY-P700220AF

	*Animal-Free LIF* Protein, Mouse (His)** Leukemia inhibitory factor; HILDA; D factor; MLPLI	Mouse	E. coli
	LIF (Leukemia Inhibitory Factor) prompts terminal differentiation in leukemic cells, inducing hematopoietic and neuronal cell differentiation. It also stimulates acute-phase protein synthesis in hepatocytes. LIF's multifaceted role underscores its significance in regulating hematopoiesis, neurogenesis, and hepatic responses. Animal-Free LIF Protein, Mouse (His) is the recombinant mouse-derived animal-FreeLIF protein, expressed by E. coli , with N-His labeled tag. The total length of Animal-Free LIF Protein, Mouse (His) is 180 a.a., with molecular weight of ~20.68 kDa.


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Cat. No.	Product Name		Classification

HY-100949

EC330 5 Publications Verification		Alkynes
EC330 is a leukemia inhibitory factor (LIF) inhibitor. EC330 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-120142

EC359 5+ Cited Publications		Alkynes
EC359 is a potent, selective, high affinity and orally active leukemia inhibitory factor receptor (LIFR) inhibitor with a K_d of 10.2 nM, which directly interacts with LIFR to effectively block LIF/LIFR interactions . EC359 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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