2. 組換えタンパク質
  3. Cytokines and Growth Factors
  4. Neurotrophic Factors
  5. Leukemia Inhibitory Factor
  6. LIF Protein, Human (HEK293, His)

LIF protein induces terminal differentiation in leukemic cells, promoting hematopoietic and neuronal cell differentiation, and stimulating acute-phase protein synthesis in hepatocytes. Its diverse activities highlight its role in influencing cellular differentiation across various cell types and physiological contexts. LIF Protein, Human (HEK293, His) is the recombinant human-derived LIF protein, expressed by HEK293 , with C-His labeled tag.

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容量 在庫状況
50 μg   お問い合わせ  
100 μg   お問い合わせ  

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製品説明

LIF protein induces terminal differentiation in leukemic cells, promoting hematopoietic and neuronal cell differentiation, and stimulating acute-phase protein synthesis in hepatocytes. Its diverse activities highlight its role in influencing cellular differentiation across various cell types and physiological contexts. LIF Protein, Human (HEK293, His) is the recombinant human-derived LIF protein, expressed by HEK293 , with C-His labeled tag.
Background

The LIF protein possesses the capacity to induce terminal differentiation in leukemic cells. Its diverse range of activities encompasses the induction of hematopoietic differentiation in both normal and myeloid leukemia cells, prompting neuronal cell differentiation, and stimulating acute-phase protein synthesis in hepatocytes. These multifaceted activities underscore LIF's role in influencing cellular differentiation across various cell types and physiological contexts.
Species

Human
Source

HEK293
Tag

C-His
Accession

P15018-1 (S23-F202)
Gene ID
Molecular Construction
N-term
LIF (S23-F202)
Accession # P15018-1
His
C-term
Protein Length

Full Length of Isoform-1 Mature Protein
Synonyms
LIF; Leukemia inhibitory factor; HILDA; D factor; MLPLI
AA Sequence

SPLPITPVNATCAIRHPCHNNLMNQIRSQLAQLNGSANALFILYYTAQGEPFPNNLDKLCGPNVTDFPPFHANGTEKAKLVELYRIVVYLGTSLGNITRDQKILNPSALSLHSKLNATADILRGLLSNVLCRLCSKYHVGHVDVTYGPDTSGKDVFQKKKLGCQLLGKYKQIIAVLAQAF

Predicted Molecular Mass
19.7 kDa
分子量

Approximately 40-55 kDa, based on SDS-PAGE under reducing conditions.
Glycosylation
Yes
純度

≥ 95%, as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
ドキュメンテーション
取扱説明書 (2659 KB)

LIF Protein, Human (HEK293, His) 関連分類

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • モル濃度計算機

  • 希釈カルキュレーター

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2

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製品名:
LIF Protein, Human (HEK293, His)
製品番号:
HY-P73278
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