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Cat. No.: HY-100949 Purity: 99.82%
Handling Instructions

EC330 is a leukemia inhibitory factor (LIF) inhibitor.

For research use only. We do not sell to patients.

EC330 Chemical Structure

EC330 Chemical Structure

CAS No. : 2016795-77-8

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 427 In-stock
Estimated Time of Arrival: December 31
1 mg USD 180 In-stock
Estimated Time of Arrival: December 31
5 mg USD 420 In-stock
Estimated Time of Arrival: December 31
10 mg USD 600 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1800 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2520 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 2 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review


EC330 is a leukemia inhibitory factor (LIF) inhibitor.

In Vitro

EC330 shows marked specificity in MCF-7 cells overexpressing LIF verses MCF-7 cells. EC330 further shows cytoskeletal disruption and targeting cancer-associated fibroblasts (CAFs) through inhibition of alpha-SMA but not beta-tubulin[1].

In Vivo

EC330 treatment (0.1, 0.5 and 2.5 mg/kg) dose dependently reduces tumor burden in ovarian (IGROV-1) and triple negative breast cancer (MDA-MB-231) cell xenografted mouse models as well as MDA-MB-231 PDX models. EC330 exhibits no reactivity towards thiol-cysteine residues, no off target binding to major receptors, kinases or ion channels. EC330 is orally bioavailable and found to be safe and tolerable in toxicity studies[1].

Molecular Weight







C[[email protected]@]12[[email protected]](O)(C(F)(F)C#C)CC[[email protected]@]1([H])[[email protected]]3([H])CCC4=CC(CCC4=C3[[email protected]@H](C5=CC=C(C6CC6)C=C5)C2)=O


Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 20 mg/mL (43.24 mM; Need ultrasonic)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1618 mL 10.8092 mL 21.6183 mL
5 mM 0.4324 mL 2.1618 mL 4.3237 mL
10 mM 0.2162 mL 1.0809 mL 2.1618 mL
*Please refer to the solubility information to select the appropriate solvent.

Purity: 99.82%

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