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Results for "

Salmonella typhimurium TA100

" in MedChemExpress (MCE) Product Catalog:

14

Inhibitors & Agonists

5

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-Z0275
    HOAT

    		Biochemical Assay Reagents Bacterial Infection
    HOAT is a peptide bond-forming reagent. HOAT is utilized to affect formation of peptide bonds by coupling carboxylic acids with amines. HOAt is not mutagenic in the bacterial reverse mutation test .
    HOAT
  • HY-W275553
    4-Decanol

    		DNA Alkylator/Crosslinker Infection
    4-Decanol is an antimutagenic compound, that can be isolated from mustard leaves. 4-Decanol inhibits mutagenic activities of Aflatoxin B1 (HY-N6615) and MNNG (HY-128612) in Salmonella typhimurium TA100 .
    4-Decanol
  • HY-W008030
    3-Aminobiphenyl

    		Bacterial Infection
    3-Aminobiphenyl is a chemical isomer of 4-ABP. 3-Aminobiphenyl can inhibit the growth of human intestinal bacteria Bifidobacterium infantis ATCC 15697, B. bifidium ATCC 11863, Clostridium perfringens ATCC 13124, Escherichia coli ATCC 25922, E. coli ATCC 35218, Enterobacter cloacae ATCC 13047 and Salmonella typhimurium TA98, TA100, YG1041. 3-Aminobiphenyl can be used as a biomarker of exposure to aromatic amines from cigarette smoke .
    3-Aminobiphenyl
  • HY-N3549
    Catalpin

    		Bacterial Infection
    Catalpin is an iridoid that can be isoalted from Catalpae Fructus.Catalpin shows mutagenic activity towards Salmonella typhimurium strain TA100 .
    Catalpin
  • HY-N17457
    N-Demethyl-N-formyldehydronuciferine

    		Bacterial Infection
    N-Demethyl-N-formyldehydronuciferine is a dehydroaporphine alkaloid. N-Demethyl-N-formyldehydronuciferine induces mutations in Salmonella typhimurium TA98 and TA100 .
    N-Demethyl-N-formyldehydronuciferine
  • HY-W150695
    1-Acetamidonaphthalene

    N-(Naphthalen-1-yl)aceTAmide

    		 Bacterial Infection
    1-Acetamidonaphthalene (N-(Naphthalen-1-yl)acetamide) is a degradation product of Digitoxigenin (HY-B2151). 1-Acetamidonaphthalene is weakly mutagenic to Salmonella typhimurium TA98 with metabolic activation. 1-Acetamidonaphthalene can be used for the research of bacterial infection .
    1-Acetamidonaphthalene
  • HY-163292
    Antibacterial agent 180

    		Bacterial Parasite Infection
    Antibacterial agent 180 (15g), an appropriate substrate for the type I nitro reductases (TcNTR I), is a promising antitrypanosomatid agent. Antibacterial agent 180 (15g) shows nonmutagenic potential against Salmonella typhimurium strains (TA98, TA100, and TA102) .
    Antibacterial agent 180
  • HY-W075176
    Transfluthrin

    		Insecticide Infection
    Transfluthrin is an insecticide with extremely low acute toxicity to vertebrates. Transfluthrin acts as a mosquito repellent, exerts mosquito control effects via electric heating fumigators, and is widely used in studies related to malaria, bancroftian filariasis and mosquito-borne infectious diseases. Transfluthrin may also induce adverse reactions such as pulmonary sensory irritation, sensitization, genotoxicity and respiratory depression, and can increase the concentrations and activities of CYP2E1 and CYP3A2 in rat brains. Transfluthrin can be removed from wastewater through biodegradation and activated sludge adsorption, and can be degraded by microorganisms such as Azovibrio and Tauera .
    Transfluthrin
  • HY-W250061
    (-)-(1S,3S)-MTCA

    		Others Cancer
    (-)-(1S,3S)-MTCA can be isolated from Japanese soy sauce. (-)-(1S,3S)-MTCA induces revertants of Salmonella typhimurium TA100, after treatment with nitrite .
    (-)-(1S,3S)-MTCA
  • HY-24366
    Quindoxin

    		Bacterial DNA/RNA Synthesis Infection
    Quindoxin is an antibacterial and growth promoter, commonly used in the livestock industry. Quindoxin exhibits clear dose-dependent mutagenic activity against Salmonella typhimurium TA98 and TA100 strains. Quindoxin can cause DNA damage and has potential genotoxicity and carcinogenic risks .
    Quindoxin
  • HY-W275553R
    4-Decanol (Standard)

    		DNA Alkylator/Crosslinker Reference Standards Infection
    4-Decanol (Standard) is the analytical standard of 4-Decanol (HY-W275553). This product is intended for research and analytical applications. 4-Decanol is an antimutagenic compound, that can be isolated from mustard leaves. 4-Decanol inhibits mutagenic activities of Aflatoxin B1 (HY-N6615) and MNNG (HY-128612) in Salmonella typhimurium TA100 .
    4-Decanol (Standard)
  • HY-W115785
    Zinc borate

    		Environmental Pollutants VEGFR RUNX Metabolic Disease
    Zinc borate is a bioactive inorganic substance with properties including osteogenic induction, pro-angiogenesis, antioxidation, antimutagenesis and cytotoxicity. In the field of bone tissue engineering, Zinc borate is often incorporated into chitosan scaffolds. By releasing zinc ions and borate ions, Zinc borate induces the differentiation of human dental pulp stem cells into osteoblasts, upregulates the expression of bone-related genes and promotes calcium deposition. Zinc borate also promotes angiogenesis by upregulating key factors such as vascular endothelial growth factor. Zinc borate exhibits antioxidant capacity to scavenge free radicals, and can specifically reduce mutagenicity under specific conditions. Zinc borate reduces the survival rate of mouse fibroblasts, but it can still be used in studies related to bone tissue engineering .
    Zinc borate
  • HY-182366
    EED-IN-5

    		Histone Methyltransferase Neurological Disease Inflammation/Immunology
    EED-IN-5 is an orally active, EZH2-selective trisubstituted pyridine-based EED-H3K27me3 inhibitor and immunomodulator with anti-inflammatory activity. The IC50 value of EED-IN-5 against EED is 28.21 nM. In mouse models, EED-IN-5 preferentially and persistently accumulates in lymph nodes after oral administration. By reducing the H3K27me3 level of dendritic cells and inhibiting their migration, EED-IN-5 decreases the infiltration of specific dendritic cells, macrophages and T cells into the spinal cord and brain. EED-IN-5 exhibits hERG inhibitory activity, shows negative results in the Mini-Ames test, and causes no obvious toxicity upon long-term high-dose administration. EED-IN-5 can be used for the research of multiple sclerosis .
    EED-IN-5
  • HY-182365
    EED-IN-4

    		Histone Demethylase Neurological Disease Inflammation/Immunology
    EED-IN-4 is an orally active, EZH2-selective immunomodulator and EED-H3K27me3 inhibitor (EED, IC50=28.21 nM) with anti-inflammatory activity. In mouse models, EED-IN-4 preferentially and persistently accumulates in lymph nodes after oral administration. By reducing the H3K27me3 level of dendritic cells and inhibiting their migration, EED-IN-4 reduces the infiltration of immune cells into the central nervous system and effectively alleviates spinal cord inflammation. EED-IN-4 shows weak inhibitory activity against hERG channels and is non-mutagenic, with no obvious toxicity observed upon long-term oral administration. EED-IN-4 can be used for the research of multiple sclerosis .
    EED-IN-4

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