3-Aminobiphenyl
Based on 1 Customer Validation
3-Aminobiphenyl is a chemical isomer of 4-ABP. 3-Aminobiphenyl can inhibit the growth of human intestinal bacteria Bifidobacterium infantis ATCC 15697, B. bifidium ATCC 11863, Clostridium perfringens ATCC 13124, Escherichia coli ATCC 25922, E. coli ATCC 35218, Enterobacter cloacae ATCC 13047 and Salmonella typhimurium TA98, TA100, YG1041. 3-Aminobiphenyl can be used as a biomarker of exposure to aromatic amines from cigarette smoke.
For research use only. We do not sell to patients.
- Purity: 99.91%
- CAS No.: 2243-47-2
- Formula: C12H11N
- Molecular Weight:169.23
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
54 μg/mL
Compound: 12
|
Cytotoxicity against HEK293 cells assessed as reduction in cell growth after 3 days by MTT assay
Cytotoxicity against HEK293 cells assessed as reduction in cell growth after 3 days by MTT assay
|
[PMID: 27259399] |
| HT-29 | IC50 |
42 μg/mL
Compound: 12
|
Cytotoxicity against human HT-29 cells assessed as reduction in cell growth after 3 days by MTT assay
Cytotoxicity against human HT-29 cells assessed as reduction in cell growth after 3 days by MTT assay
|
[PMID: 27259399] |
| MCF7 | IC50 |
60 μg/mL
Compound: 12
|
Cytotoxicity against human MCF7 cells assessed as reduction in cell growth after 3 days by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell growth after 3 days by MTT assay
|
[PMID: 27259399] |
Chemical Information
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CAS No. 2243-47-2
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Appearance <28°C Solid,>33°C Liquid
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Molecular Weight 169.23
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Formula C12H11N
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Color Colorless to white
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SMILES
NC1=CC=CC(=C1)C=2C=CC=CC2
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (597 KB)
- English - EN (597 KB)
- Français - FR (597 KB)
- Deutsch - DE (597 KB)
- Norwegian - NO (597 KB)
- Español - ES (597 KB)
- Swedish - SV (597 KB)
- Italian - IT (597 KB)
- Korean - KR (597 KB)
- Portuguese - PT (597 KB)
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Handling Instructions (2659 KB)
References
[1]. Chung, K. T., & Adris, P. (2003). Growth inhibition of intestinal bacteria and mutagenicity of 2-, 3-, 4-aminobiphenyls, benzidine, and biphenyl. Toxicology in vitro : an international journal published in association with BIBRA, 17(2), 145-152. [Content Brief]
[2]. Sarkar, M., et al., (2006). CYP1A2 and NAT2 phenotyping and 3-aminobiphenyl and 4-aminobiphenyl hemoglobin adduct levels in smokers and non-smokers. Toxicology and applied pharmacology, 213(3), 198-206. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)