HOAT
Based on 1 Customer Validation
HOAT is a peptide bond-forming reagent. HOAT is utilized to affect formation of peptide bonds by coupling carboxylic acids with amines. HOAt is not mutagenic in the bacterial reverse mutation test.
For research use only. We do not sell to patients.
- Purity: 99.97%
- CAS No.: 39968-33-7
- Formula: C5H4N4O
- Molecular Weight:136.11
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
HOAT (1.60-5000 μg/plate) shows no mutagenicity in the bacterial reverse mutation (Ames) assay using Salmonella typhimurium strains TA98, TA100, TA1535, TA1537 and Escherichia coli strain WP2 uvrA[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 39968-33-7
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Appearance Solid
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Molecular Weight 136.11
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Formula C5H4N4O
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Color White to yellow
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SMILES
ON1C2=NC=CC=C2N=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 175 mg/mL (1285.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (604 KB)
- English - EN (604 KB)
- Français - FR (604 KB)
- Deutsch - DE (604 KB)
- Norwegian - NO (604 KB)
- Español - ES (604 KB)
- Swedish - SV (604 KB)
- Italian - IT (604 KB)
- Korean - KR (604 KB)
- Portuguese - PT (604 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.3470 mL | 36.7350 mL | 73.4700 mL | 183.6750 mL |
| 5 mM | 1.4694 mL | 7.3470 mL | 14.6940 mL | 36.7350 mL | |
| 10 mM | 0.7347 mL | 3.6735 mL | 7.3470 mL | 18.3675 mL | |
| 15 mM | 0.4898 mL | 2.4490 mL | 4.8980 mL | 12.2450 mL | |
| 20 mM | 0.3673 mL | 1.8367 mL | 3.6735 mL | 9.1837 mL | |
| 25 mM | 0.2939 mL | 1.4694 mL | 2.9388 mL | 7.3470 mL | |
| 30 mM | 0.2449 mL | 1.2245 mL | 2.4490 mL | 6.1225 mL | |
| 40 mM | 0.1837 mL | 0.9184 mL | 1.8367 mL | 4.5919 mL | |
| 50 mM | 0.1469 mL | 0.7347 mL | 1.4694 mL | 3.6735 mL | |
| 60 mM | 0.1224 mL | 0.6122 mL | 1.2245 mL | 3.0612 mL | |
| 80 mM | 0.0918 mL | 0.4592 mL | 0.9184 mL | 2.2959 mL | |
| 100 mM | 0.0735 mL | 0.3673 mL | 0.7347 mL | 1.8367 mL |