Search Result
Results for "
Transfection
" in MedChemExpress (MCE) Product Catalog:
15
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-112301A
-
|
trans-BLU-667
|
RET
|
Cancer
|
|
trans-Pralsetinib (trans-BLU-667) is a rearranged during transfection (RET) inhibitor extracted from patent US20170121312A1, Compound Example 129 .
|
-
-
- HY-112754A
-
|
1,2-Dioleoyl-3-trimethylammonium-propane chloride
|
Liposome
|
Cancer
|
|
DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid .
|
-
-
- HY-139200
-
|
|
Liposome
|
Others
|
|
DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo .
|
-
-
- HY-W800783
-
|
CDESA
|
Liposome
|
Others
|
|
DSTAP chloride (CDESA) is a cationic lipid that used in the formation of lipid nanoparticles (LNPs). DORI chloride has high transfection efficiency .
|
-
-
- HY-142997
-
|
|
Liposome
|
Others
|
|
DOSPA is a cationicliposome. DOSPA can formulate with DNA to be a transfection system. DOSPA can be used for gene therapy research .
|
-
-
- HY-144015
-
|
|
Liposome
|
Others
|
|
14:1 EPC trifluoromethanesulfonate is ethyl-phosphatidylcholine (EPC) with monounsaturated 14:1 chains. 14:1 EPC trifluoromethanesulfonate shows transfection activity. 14:1 EPC trifluoromethanesulfonate can be used for drug delivery .
|
-
-
- HY-149037
-
|
N4-Spermine cholesteryl carbamate
|
Liposome
|
Others
|
|
GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
|
-
-
- HY-112005
-
|
dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
|
Liposome
Endogenous Metabolite
|
Inflammation/Immunology
|
|
DOPE (dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
|
-
-
- HY-149037A
-
|
N4-Spermine cholesteryl carbamate pentahydrochloride
|
Liposome
|
Others
|
|
GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
|
-
-
- HY-P0311
-
|
|
Bacterial
|
Infection
|
|
LAH4, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 possesses high plasmid DNA delivery capacities. LAH4 has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes .
|
-
-
- HY-P0311A
-
|
|
Bacterial
|
Infection
|
|
LAH4 TFA, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 TFA possesses high plasmid DNA delivery capacities. LAH4 TFA has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes .
|
-
-
- HY-W250110
-
|
|
Biochemical Assay Reagents
|
Infection
Others
|
|
Polyethylenimine (PEI) branched is a organic macromolecule with high cationic-charge-density potential. PEI can ensnare DNA as well as attach to cell membrane, PEI also retains a substantial buffering capacity at virtually any pH. PEI is widely used as transfection reagent .
|
-
-
- HY-153082
-
|
|
Fluorescent Dye
|
Others
|
|
Firefly Luciferase circRNA will express a luciferase protein, originally isolated from the Photinus pyralis (Firefly). Firefly Luciferase circRNA is ideal for monitoring and optimizing transfection efficiency and is recommended as a positive control for circular RNA transfections.
|
-
-
- HY-W590549
-
|
DODAC
|
Others
|
Others
|
|
Dioleyldimethylammonium chloride (DODAC) is a cationic lipid that can be used as transfection reagent .
|
-
-
- HY-W127378
-
|
1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate
|
Biochemical Assay Reagents
|
Others
|
|
DOTAP Transfection Reagent is a cationic derivative of trimethylammonium attached to two 18-carbon fatty acid tails, each with a single alkene group. 18:1 TAP is a cationic liposome-forming compound useful for the transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells.
|
-
-
- HY-144022
-
-
-
- HY-153081
-
|
|
Fluorescent Dye
|
Others
|
|
The eGFP circRNA will express green fluorescent protein, originally isolated from the jellyfish, Aequorea victoria. The eGFP is a commonly used direct detection reporter in mammalian cell culture, yielding bright green fluorescence with an emission peak at 509 nm. The eGFP circRNA is therefore ideal for monitoring and optimizing transfection efficiency and is recommended as a positive control for circular RNA transfections.
|
-
-
- HY-34595
-
|
|
RET
|
Cancer
|
|
Pyrazoloadenine is a potent RET (REarranged during Transfection) lung cancer oncoprotein inhibitor. Pyrazoloadenine shows anticancer activity .
|
-
-
- HY-W800776
-
|
1,2-Dioleoyl-3-dimethyl-hydroxyethylammonium bromide
|
Liposome
|
Others
|
|
DORI is a cationic lipid that can deliver plasmid DNA in vitro. DORI has lower cytotoxicity and high transfection efficiency .
|
-
-
- HY-145024
-
|
|
RET
|
Cancer
|
|
RET-IN-6 is a potent RET (rearranged during transfection) inhibitor with an IC50 of 4.57 nM (CN113461670A, compound 321) .
|
-
-
- HY-125529
-
|
Chol-T
|
Liposome
|
Others
|
|
DMPAC-Chol (Chol-T) is used for liposome formation. DMPAC-Chol (Chol-T) liposomes exhibits great transfection effciencies .
|
-
-
- HY-148842
-
|
|
Liposome
|
Others
|
|
C14-4 is an ionizable lipid for lipid nanoparticles (LNPs) formulation. C14-4 was identified for its potent transfection and low cytotoxicity.
|
-
-
- HY-W590680
-
|
|
Liposome
|
Others
|
|
ssPalmM is a SS-cleavable proton-activated lipid-like materials. ssPalmM can be used to form lipid nanoparticles (LNPs) for nuclear targeting of plasmid DNA .
|
-
-
- HY-151862
-
|
|
ADC Linker
|
Others
|
|
3-Azidopropylamine is a click chemistry reagent containing an azide group. 3-Azidopropylamine can react with the starch sugar of potato starch for complexation and transfection of plasmid DNA .
|
-
-
- HY-144422
-
|
|
RET
|
Cancer
|
|
RET-IN-15 is a rearranged during transfection (RET) kinase inhibitor extracted from patent WO2021115457A1 compound 51. RET-IN-15 can be used for the research of cancer .
|
-
-
- HY-125734
-
|
|
Liposome
|
Others
|
|
DMHAPC-Chol, a cationic lipid, contains a biodegradable carbamoyl linker and a hydroxyethyl group in the polar amino head moiety. DMHAPC-Chol can be used in both transfection experiments concerning plasmids or siRNA .
|
-
-
- HY-145023
-
|
|
RET
|
Cancer
|
|
RET-IN-5 is a potent RET (rearranged during transfection) inhibitor with an IC50s of 0.4 nM and 135.1 nM for RET and VEGFR2, respectively (WO2021213476A1, compound 18) .
|
-
-
- HY-144016
-
|
|
Liposome
|
Others
|
|
16:0 EPC chloride, a P-O-ethyl derivative, is a saturated cationic lipid. 16:0 EPC chloride can serve as a DNA and RNA transfecting agent. 16:0 EPC chloride can be used as a co-adjuvant for preparing vaccines and promote drug delivery .
|
-
-
- HY-W590676
-
|
TMCL
|
Liposome
|
Others
|
|
Tetramyristoylcardiolipin (TMCL) is an anionic lipid. Tetramyristoylcardiolipin can be used to study cell membrane function and drug delivery .
|
-
-
- HY-143545
-
|
|
RET
|
Cancer
|
|
RET-IN-8 is a rearranged during transfection (RET) kinase inhibitor extracted from patent WO2021093720A1 compound I-1. RET-IN-8 can be used for the research of cancer .
|
-
-
- HY-156936
-
|
|
Liposome
|
Others
|
|
RCB-02-4-8 is an ionizable cationic lipid that is used to form lipid nanoparticles (LNPs) to deliver mRNA. RCB-02-4-8 can improve the efficiency of lung transfection in mice .
|
-
-
- HY-148859
-
-
-
- HY-W440827
-
|
|
PROTAC Linkers
|
Cancer
|
|
DOPE-PEG-COOH (MW 2000) is a PEG-based PROTAC linker. DOPE-PEG-COOH (MW 2000) can be used in the synthesis of PROTACs. DOPE-PEG-COOH (MW 2000) can be used for drug delivery, gene transfection and vaccine delivery .
|
-
-
- HY-W598178
-
|
|
Liposome
|
Others
|
|
93-O17O is a chalcogen-containing ionizable cationic lipidoid that used in the formation of lipid nanoparticles (LNPs) .
|
-
-
- HY-134541
-
SM-102
Maximum Cited Publications
7 Publications Verification
|
Liposome
|
Infection
|
|
SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
|
-
-
- HY-112764
-
|
|
Liposome
|
Metabolic Disease
|
|
DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
|
-
-
- HY-145973
-
|
m7(3'OMeG)(5')ppp(5')(2'OMeA)pG
|
DNA/RNA Synthesis
|
Others
|
|
3'OMe-m7GpppAmpG is a trinucleotide Cap analogue. 3'OMe-m7GpppAmpG shows a significant translational efficiency. 3'OMe-m7GpppAmpG can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization .
|
-
-
- HY-145973A
-
|
m7(3'OMeG)(5')ppp(5')(2'OMeA)pG ammonium
|
DNA/RNA Synthesis
|
Others
|
|
3'OMe-m7GpppAmpG ammonium is a trinucleotide Cap analogue. 3'OMe-m7GpppAmpG ammonium shows a significant translational efficiency. 3'OMe-m7GpppAmpG ammonium can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization .
|
-
-
- HY-116116
-
|
SIM010603
|
c-Kit
RET
VEGFR
|
Cancer
|
|
Tafetinib (SIM010603) is an oral multi-targets receptor tyrosine kinases inhibitor. Tafetinib inhibitsstem cell factor receptor (Kit),vascular endothelial growth factor receptor-2 (VEGFR-2),platelet-derived growth factor receptor-β (PDGFR-β),glial cell line-derived neurotrophic factor receptor (Rearranged during Transfection; RET), andFms-like tyrosine kinase-3 (FLT3)withIC50values between 5.0 and 68.1 nmol/l. Tafetinib inhibits the phosphorylation ofPDGFR-βandVEGFR-2. Tafetinib inhibits endothelial cell proliferation, endothelial cells chemotaxis, and corneal angiogenesis .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-112754A
-
|
1,2-Dioleoyl-3-trimethylammonium-propane chloride
|
Drug Delivery
|
|
DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid .
|
-
- HY-139200
-
|
|
Drug Delivery
|
|
DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo .
|
-
- HY-142997
-
|
|
Drug Delivery
|
|
DOSPA is a cationicliposome. DOSPA can formulate with DNA to be a transfection system. DOSPA can be used for gene therapy research .
|
-
- HY-144015
-
|
|
Drug Delivery
|
|
14:1 EPC trifluoromethanesulfonate is ethyl-phosphatidylcholine (EPC) with monounsaturated 14:1 chains. 14:1 EPC trifluoromethanesulfonate shows transfection activity. 14:1 EPC trifluoromethanesulfonate can be used for drug delivery .
|
-
- HY-149037
-
|
N4-Spermine cholesteryl carbamate
|
Drug Delivery
|
|
GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
|
-
- HY-112005
-
|
dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
|
Drug Delivery
|
|
DOPE (dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
|
-
- HY-149037A
-
|
N4-Spermine cholesteryl carbamate pentahydrochloride
|
Drug Delivery
|
|
GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
|
-
- HY-W127378
-
|
1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate
|
Biochemical Assay Reagents
|
|
DOTAP Transfection Reagent is a cationic derivative of trimethylammonium attached to two 18-carbon fatty acid tails, each with a single alkene group. 18:1 TAP is a cationic liposome-forming compound useful for the transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells.
|
-
- HY-144022
-
|
|
Drug Delivery
|
|
16:0 DAP is a cationic lipids that can be used for drug delivery, gene transfection and vaccine delivery .
|
-
- HY-148842
-
|
|
Drug Delivery
|
|
C14-4 is an ionizable lipid for lipid nanoparticles (LNPs) formulation. C14-4 was identified for its potent transfection and low cytotoxicity.
|
-
- HY-144016
-
|
|
Drug Delivery
|
|
16:0 EPC chloride, a P-O-ethyl derivative, is a saturated cationic lipid. 16:0 EPC chloride can serve as a DNA and RNA transfecting agent. 16:0 EPC chloride can be used as a co-adjuvant for preparing vaccines and promote drug delivery .
|
-
- HY-148859
-
|
|
Drug Delivery
|
|
AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid). AA-T3A-C12 mediates great RNA delivery and transfection of activated fibroblasts .
|
-
- HY-134541
-
SM-102
Maximum Cited Publications
7 Publications Verification
|
Drug Delivery
|
|
SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
|
-
- HY-112764
-
|
|
Drug Delivery
|
|
DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
|
-
- HY-145973A
-
|
m7(3'OMeG)(5')ppp(5')(2'OMeA)pG ammonium
|
Gene Sequencing and Synthesis
|
|
3'OMe-m7GpppAmpG ammonium is a trinucleotide Cap analogue. 3'OMe-m7GpppAmpG ammonium shows a significant translational efficiency. 3'OMe-m7GpppAmpG ammonium can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P0311A
-
|
|
Bacterial
|
Infection
|
|
LAH4 TFA, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 TFA possesses high plasmid DNA delivery capacities. LAH4 TFA has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes .
|
-
- HY-P2530
-
|
|
Peptides
|
Others
|
|
KALA is an amphiphilic peptide that forms an α-helical structure at physiological pH. KALA modifies a plasmid DNA-encapsulating liposomal membrane and is used as a fusogenic peptide in order to achieve effective liver targeting and transfection of DNA via galactose receptors .
|
-
- HY-P0311
-
|
|
Bacterial
|
Infection
|
|
LAH4, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 possesses high plasmid DNA delivery capacities. LAH4 has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes .
|
-
- HY-K2015
-
|
|
|
MCE Lentivirus Transfection Reagent is a new type of transfection reagent based on cationic polymer, which is suitable for lentivirus packaging and transfection. It significantly improves the efficiency of packaging and transfection, resulting in the production of more recombinant lentivirus.
|
-
- HY-K2016
-
|
|
|
MCE Protein Transfection Reagent is a cationic lipid mixture for complexation with proteins, peptides, antibodies and other biologically active molecules to allow their direct intracellular delivery.
|
-
- HY-K1014
-
|
|
|
MCE PolyFast Transfection Reagent consists of cationic polymers and can introduce nucleic acids (DNA or RNA) into eukaryotic cells efficiently, including some hard-to-transfect cells.
|
-
- HY-K2014
-
3 Publications Verification
|
|
MCE PEI Transfection Reagent is designed based on 25 kDa PEI. It has high-efficiency, low-toxicity, strong-stability, and is suitable for many cell types, such as HEK-293、HEK-293T、CHO-K1、COS-1、COS-7、NIH/3T3、Sf9、HepG2 and HeLa et, even some hard-to-transfect cells. It can also be applied to large-scale recombinant protein expression and virus production.
|
-
- HY-K2017
-
|
|
|
MCE siRNA/miRNA Transfection Reagent is a novel cationic polymer transfection reagent for siRNA and miRNA transfection.
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-151862
-
|
|
|
Azide
|
|
3-Azidopropylamine is a click chemistry reagent containing an azide group. 3-Azidopropylamine can react with the starch sugar of potato starch for complexation and transfection of plasmid DNA .
|
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent:
