Polyethylenimine (branched) (30% in water)
Based on 9 publication(s) in Google Scholar
Polyethylenimine (branched) (30% in water) is a organic macromolecule with high cationic-charge-density potential. Polyethylenimine (branched) (30% in water) can ensnare DNA as well as attach to cell membrane. Polyethylenimine (branched) (30% in water) also retains a substantial buffering capacity at virtually any pH. Polyethylenimine (branched) (30% in water) is widely used as transfection reagent.
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- CAS. Nr.: 9002-98-6
- Formel: (C2H5N)x
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Speicherung:
Solution, -20°C, protect from light, 2 years
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Biologische Aktivität
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) Polyethylenimine (branched) (30% in water)
More- Nat Commun. 2024 Aug 2;15(1):6511. [Abstract]
- J Extracell Vesicles. 2025 Nov;14(11):e70186. [Abstract]
- J Immunother Cancer. 2025 Jun 8;13(6):e011642. [Abstract]
- Cell Death Dis. 2024 Mar 14;15(3):216. [Abstract]
- Cell Rep. 2026 Mar 24;45(4):117193. [Abstract]
- Clin Transl Med. 2025 Feb;15(2):e70231. [Abstract]
- Noncoding RNA Res. 2025 Feb 22:12:42-55. [Abstract]
- Endocrine. 2026 May 2;91(1):151. [Abstract]
- Prostate. 2024 Mar;84(4):317-328. [Abstract]
Biologische Aktivität
Polyethylenimine branched (ranged PEI/DNA ratio, 24 h) reaches maximal transfection efficiency at 9-13.5 equivalents of PEI nitrogen per DNA phosphate and does not affect cell metabolism in 3T3 cells. [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS. Nr. 9002-98-6
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Appearance Liquid
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Formel (C2H5N)x
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Color Colorless to light yellow
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SMILES
NCCN(CCN)CCN(CCCNCN)CCN(CCNCCN)CCNCCN(CCN)CCN.[n]
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Solution, -20°C, protect from light, 2 years
Publications (9)
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Journal Impact Factor
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Most Recent
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Nat Commun
Engineering of a mammalian VMAT2 for cryo-EM analysis results in non-canonical protein folding. [Abstract]2024 Aug 2;15(1):6511. PMID: 39095428 -
J Extracell Vesicles
Efficient Scaling up EV-AAVs Production via Cellular Nanoporation for Familial Hypercholesterolaemia Therapy. [Abstract]2025 Nov;14(11):e70186. PMID: 41216903 -
J Immunother Cancer
Preclinical and clinical evaluation of intratumoral injection of an IL-12 expressing SKV-012 oncolytic virus for advanced solid tumors. [Abstract]2025 Jun 8;13(6):e011642. PMID: 40484644 -
Cell Death Dis
Histidine re-sensitizes pediatric acute lymphoblastic leukemia to 6-mercaptopurine through tetrahydrofolate consumption and SIRT5-mediated desuccinylation. [Abstract]2024 Mar 14;15(3):216. PMID: 38485947 -
Cell Rep
Astrocytic AEBP1-NPAS3-LIPA pathway coordinates cholesterol homeostasis to regulate Alzheimer's pathology. [Abstract]2026 Mar 24;45(4):117193. PMID: 41880326 -
Clin Transl Med
SHP2 inhibition and adjuvant therapy synergistically target KIT-mutant GISTs via ERK1/2-regulated GSK3β/cyclin D1 pathway. [Abstract]2025 Feb;15(2):e70231. PMID: 39981588 -
Noncoding RNA Res
LncRNA APTR amplification serves as a potential glioma biomarker and promotes glioma progression via miR-6734-5p/ TCF7/LEF1 axis. [Abstract]2025 Feb 22:12:42-55. PMID: 40103614 -
Endocrine
Single-nucleus RNA sequencing reveals the cellular composition and the mechanism underlying adrenal myelolipoma. [Abstract]2026 May 2;91(1):151. PMID: 42067723 -
Prostate
PrLZ regulates EMT and invasion in prostate cancer via the TGF-β1/p-smad2/miR-200 family/ZEB1 axis. [Abstract]2024 Mar;84(4):317-328. PMID: 38145367
Reinheit & Dokumentation
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Data Sheet (269 KB)
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SDS (537 KB)
- English - EN (537 KB)
- Français - FR (537 KB)
- Deutsch - DE (537 KB)
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- Español - ES (537 KB)
- Swedish - SV (537 KB)
- Italian - IT (537 KB)
- Korean - KR (537 KB)
- Portuguese - PT (537 KB)
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Handling Instructions (2659 KB)
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Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Polyethylenimine (branched) (30% in water) Related Classifications
HY-W250110 Related Classifications
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