2. Metabolic Enzyme/Protease
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  4. GL67

GL67  (Synonyms: N4-Spermine cholesteryl carbamate)

Cat. No.: HY-149037
Handling Instructions

Molarity Calculator

GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (GL67 pentahydrochloride) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

GL67 Chemical Structure

GL67 Chemical Structure

CAS No. : 179075-30-0

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GL67 Related Antibodies

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Description

GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection[1].

Molecular Weight

614.99

Formula

C38H70N4O2
CAS No.
SMILES

C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OC(N(CCCN)CCCCNCCCN)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 16.67 mg/mL (27.11 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6260 mL 8.1302 mL 16.2604 mL
5 mM 0.3252 mL 1.6260 mL 3.2521 mL
View the Complete Stock Solution Preparation Table

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6260 mL 8.1302 mL 16.2604 mL 40.6511 mL
5 mM 0.3252 mL 1.6260 mL 3.2521 mL 8.1302 mL
10 mM 0.1626 mL 0.8130 mL 1.6260 mL 4.0651 mL
15 mM 0.1084 mL 0.5420 mL 1.0840 mL 2.7101 mL
20 mM 0.0813 mL 0.4065 mL 0.8130 mL 2.0326 mL
25 mM 0.0650 mL 0.3252 mL 0.6504 mL 1.6260 mL
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GL67 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GL67179075-30-0N4-Spermine cholesteryl carbamateGL 67GL-67Liposomelipidnucleic acidvaccinedeliverygene transfectionInhibitorinhibitorinhibit

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