13 Results for "

antimelanogenesis

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "antimelanogenesis" in MCE Product Catalog:

1
Methyl linolenate
Methyl linolenate
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1 Cited Publications
Cat. No.: HY-21268
CAS No.: 301-00-8
Synonyms: Linolenic acid methyl ester
Category:  

other families Other Diseases Lipids Plants Disease Research Fields

Target:  

Environmental Pollutants Melatonin Receptor

Methyl linolenate is a polyunsaturated fattly acid (PUFA). Methyl linolenate has an anti-melanogenesis activity with an IC50 of 60 μM. Methyl linolenate can also be used for studies of the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids .
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Valencene
Valencene
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1 Cited Publications
Cat. No.: HY-N6636
CAS No.: 4630-07-3
Category:  

Terpenoids Sesquiterpenes Cyperaceae Cyperus rotundus L. Plants Disease Research Fields Inflammation/Immunology

Target:  

NF-κB Interleukin Related

Valencene is a sesquiterpene that can be isolated from Cyperus rotundus. Valencene possesses antiallergic, antimelanogenesis, anti-infammatory, and antioxidant activitivies. Valencene inhibits the exaggerated expression of Th2 chemokines and proinflammatory chemokines through blockade of the NF-κB pathway. Valencene inhibits the production and expression of proinflammatory cytokines IL-1β and IL-6 in LPS-stimulated RAW 264.7 cells. Valencene can reduce atopic dermatitis symptoms and recover decreased expression of filaggrin in DNCB-sensitized mouse model .
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Gomisin N
Gomisin N
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Cat. No.: HY-N6866
CAS No.: 69176-52-9
Category:  

Neurological Disease Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Inflammation/Immunology Schisandra chinensis (Turcz.) Baill. Cancer

Target:  

Apoptosis AMPK Akt PERK Keap1-Nrf2 Caspase PARP GSK-3 NO Synthase Interleukin Related

Gomisin N is an orally active lignan compound. Gomisin N can be isolated from Schisandra chinensis. Gomisin N induces Apoptosis in a variety of cells. Gomisin N activates AMPK, Akt, MAPK/ERK, Nrf2, caspase-3 and PARP-1. Gomisin N inhibits GSK3β, nitric oxide (NO), and proinflammatory cytokines (IL-1β, IL-6, TNF-α). Gomisin N has anti-inflammatory, antioxidant, anti-obesity, anti-diabetic, and anti-melanogenesis activities. Gomisin N has anti-tumor activity against cervical cancer and liver cancer. Gomisin N improves Alzheimer's disease .
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Gomisin D
Gomisin D
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Cat. No.: HY-N2413
CAS No.: 60546-10-3
Category:  

Lignans Metabolic Disease Phenylpropanoids Plants Schisandraceae Disease Research Fields Schisandra chinensis (Turcz.) Baill.

Target:  

PDGFR UGT Reactive Oxygen Species (ROS) Apoptosis Tyrosinase p38 MAPK Akt ERK COX Interleukin Related

Gomisin D is an orally active lignan that binds to PDGFRβ with a Kd of 10 μM. By targeting PDGFRβ to regulate signaling pathways, Gomisin D inhibits the activation and proliferation of hepatic stellate cells and promotes their apoptosis, thereby ameliorating hepatic fibrosis. Gomisin D exhibits multiple activities such as photoprotection, antimelanogenesis, antioxidant effects, and hypoglycemic activity. Gomisin D can be used in studies related to diabetes, Alzheimer's disease, and hepatic fibrosis .
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β-Tocopherol
β-Tocopherol
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Cat. No.: HY-133680
CAS No.: 16698-35-4
Purity:  99.64%
Category:  

Monophenols Metabolic Disease Phenols Plants Palmae Disease Research Fields Trachycarpus fortunei (Hook.) H. Wendl.

Target:  

Tyrosinase

β-Tocopherol is an analogue of vitamin E, exhibits antioxidant properties. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol also can prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol .
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Ethyl linolenate
Ethyl linolenate
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Cat. No.: HY-N2073
CAS No.: 1191-41-9
Category:  

Cardiovascular Disease other families Lipids Plants Disease Research Fields

Target:  

MCHR1 (GPR24)

Ethyl linolenate is a fatty acid ethyl ester (FAEE). Ethyl linolenate plays an active role in inhibition of the cellular production on melanin with an IC50 of 70 μM. Anti-melanogenesis Effects .
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Ginsenoside C-Y
Ginsenoside C-Y
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Cat. No.: HY-N9389
CAS No.: 83480-65-3
Synonyms: Ginsenoside Y
Category:  

Triterpenes Microorganisms Terpenoids Metabolic Disease Disease Research Fields

Target:  

Drug Metabolite

Ginsenoside C-Y (Ginsenoside Y) is a metabolite of Ginsenoside Rb2 (HY-N0040). Ginsenoside C-Y exhibits anti-photoaging and anti-melanogenesis properties .
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Valencene (Standard)
Valencene (Standard)
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Cat. No.: HY-N6636R
CAS No.: 4630-07-3
Category:  

Terpenoids Cyperaceae Cyperus rotundus L. Plants Disease Research Fields Inflammation/Immunology

Target:  

Reference Standards NF-κB Interleukin Related

Valencene (Standard) is the analytical standard of Valencene. This product is intended for research and analytical applications. Valencene is a sesquiterpene that can be isolated from Cyperus rotundus. Valencene possesses antiallergic, antimelanogenesis, anti-infammatory, and antioxidant activitivies. Valencene inhibits the exaggerated expression of Th2 chemokines and proinflammatory chemokines through blockade of the NF-κB pathway. Valencene inhibits the production and expression of proinflammatory cytokines IL-1β and IL-6 in LPS-stimulated RAW 264.7 cells. Valencene can reduce atopic dermatitis symptoms and recover decreased expression of filaggrin in DNCB-sensitized mouse model .
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1,2,4,6-Tetra-O-galloyl-β-D-glucose
1,2,4,6-Tetra-O-galloyl-β-D-glucose
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Cat. No.: HY-N15572
CAS No.: 84297-49-4
Category:  

Myrtaceae Phenols Polyphenols Plants Eucalyptus globulus Labill.

Target:  

SOD

1,2,4,6-Tetra-O-galloyl-β-D-glucose is an antioxidant found in Eucalyptus globulus. 1,2,4,6-Tetra-O-galloyl-β-D-glucose has significant superoxide dismutase (SOD)-like antioxidant activity (EC50: 1.55 μM). 1,2,4,6-Tetra-O-galloyl-β-D-glucose can inhibit tyrosinase (IC50: 0.59 mM) and hyaluronidase (IC50: 0.68 mM). 1,2,4,6-Tetra-O-galloyl-β-D-glucose can be used in food antioxidants, cosmetics anti-melanogenesis and anti-allergy/anti-inflammatory research .
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Apovincamine
Apovincamine
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Cat. No.: HY-135743
CAS No.: 4880-92-6
Synonyms: cis-Apovincamine; (+)-Apovincamine
Category:  

Apocynaceae Alkaloids Alstonia yunnanensis Diels Plants Disease Research Fields Cancer Indole Alkaloids

Target:  

Tyrosinase

Apovincamine (cis-Apovincamine) is an indole alkaloid isolated from the Malaysian Alstonia pneumatophora (Apocynaceae). Apovincamine shows anti-melanogenesis activity .
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Ethyl linolenate-d5
Ethyl linolenate-d5
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Cat. No.: HY-N2073S
CAS No.: 203633-16-3
Ethyl linolenate-d5 is the deuterium labeled Ethyl linolenate. Ethyl linolenate is a fatty acid ethyl ester (FAEE). Ethyl linolenate plays an active role in inhibition of the cellular production on melanin with an IC50 of 70 μM. Anti-melanogenesis Effects .
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Methyl-d3 Linolenate
Methyl-d3 Linolenate
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Cat. No.: HY-W744883
Methyl-d3 Linolenate is the deuterium labeled Methyl linolenate (HY-21268). Methyl linolenate is a polyunsaturated fattly acid (PUFA). Methyl linolenate has an anti-melanogenesis activity with an IC50 of 60 μM. Methyl linolenate can also be used for studies of the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids .
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AP736
AP736
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Cat. No.: HY-157010
CAS No.: 1365531-21-0
Target:  

Tyrosinase PKA

Research Areas:  

Others

AP736 is a potent tyrosinase inhibitor (IC50 = 0.9 μM) with anti-melanogenesis activity in normal human melanocytes (IC50 = 0.11 μM). AP736 suppresses the expression of tyrosinase and TRP-1/2 by inhibiting the cAMP-PKA-CREB signalling axis, leading to reduced microphthalmia-associated transcription factor (MITF) transcripts and proteins. AP736 can be used for melanogenesis and hyperpigmentation research .
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