1. Alkaloids
  2. Apovincamine

Apovincamine (Synonyms: cis-Apovincamine; (+)-Apovincamine)

Cat. No.: HY-135743
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Apovincamine (cis-Apovincamine) is an indole alkaloid isolated from the Malaysian Alstonia pneumatophora (Apocynaceae). Apovincamine shows anti-melanogenesis activity.

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Apovincamine Chemical Structure

Apovincamine Chemical Structure

CAS No. : 4880-92-6

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Description

Apovincamine (cis-Apovincamine) is an indole alkaloid isolated from the Malaysian Alstonia pneumatophora (Apocynaceae). Apovincamine shows anti-melanogenesis activity[1].

In Vitro

Apovincamine (cis-Apovincamine; 6.3, 12.5, 25, 50, 100 μM) dose-dependently inhibits cells viability with an IC50 of 49.8 μM and shows anti-melanogenesis in B16 mouse melanoma cells[1].

Molecular Weight

336.43

Formula

C₂₁H₂₄N₂O₂

CAS No.

4880-92-6

SMILES

[H][[email protected]]12[[email protected]]3(CC)C=C(C(OC)=O)N(C4=CC=CC=C45)C1=C5CCN2CCC3

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Apovincaminecis-Apovincamine(+)-ApovincamineOthersindolealkaloidanti-melanogenesisB16mousemelanomaInhibitorinhibitorinhibit

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