Search Result

Pathways Recommended:	Metabolic Enzyme/Protease

Results for "

detoxification enzyme

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (1) Biochemical Assay Reagents (3) Cytochrome P450 (1) Drug Metabolite (1) Endogenous Metabolite (5) Environmental Pollutants (1) GABA Receptor (1) Glutathione S-transferase (4) Glycosidase (1) Keap1-Nrf2 (1) Quinone Reductase (2) Reference Standards (1) SOD (1)
By Research Areas:	Cancer (12) Cardiovascular Disease (1) Infection (2) Inflammation/Immunology (3) Metabolic Disease (6) Neurological Disease (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Targets Recommended: Peroxidase Enzyme E1/E2/E3 Enzyme Carnosine-cleaving Enzyme Proteolytic Enzyme Endothelin-Converting Enzyme (ECE) Angiotensin-converting Enzyme (ACE) IRE1 NEDD8-activating Enzyme IDE TET Protein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y1683

DL-Menthol Racementhol	Environmental Pollutants GABA Receptor	Infection Neurological Disease
DL-Menthol (Racementhol) is an orally active, GABA_aR positive allosteric modulator and UDP-glucuronosyltransferase (UGT) inhibitor that can cross the blood-brain barrier. DL-Menthol binds to GABA_AR and exhibits an allosteric activation effect, enhancing GABA-mediated chloride influx and inhibiting neuronal excitability. DL-Menthol can induce surgical anesthesia in fish and inhibit the metabolic detoxification of tobacco carcinogens by human liver and intestinal UGT enzymes, resulting in reduced NNAL-N-Gluc production .

HY-N0548

α-Angelica lactone 2 Publications Verification	Glutathione S-transferase	Cancer
α-Angelica lactone is a naturally occurring anticarcinogen and an vinylogous nucleophile. α-Angelica lactone can give the chiral δ-amino γ,γ-disubstituted butenolide carbonyl derivatives and exhibitselectrophilic trapping at the γ-carbon. α-Angelica lactone exerts strong chemoprotective effects by selective enhancement of glutathione-S-thansferase (GST) and UDP-glucononosyltransferase (UGT) detoxification enzymes .

HY-150097

Recombinant Human Serum Albumin(rHSA)	Biochemical Assay Reagents	Metabolic Disease Inflammation/Immunology Cancer
Recombinant Human Serum Albumin (rHSA) is a non-glycosylated monomeric plasma protein that acts as a core factor for maintaining plasma colloid osmotic pressure. Recombinant Human Serum Albumin (rHSA) possesses multiple physiological functions including carrier, metabolic regulation, detoxification, antioxidation and enzyme mimicking. Recombinant Human Serum Albumin (rHSA) not only scavenges reactive oxygen and nitrogen species via specific residues and binds a variety of endogenous and exogenous compounds to maintain redox homeostasis, but also serves as a biomarker for multiple diseases such as cancer and inflammation. Recombinant Human Serum Albumin (rHSA) broadly supports the development of implantable materials, surgical adhesives and ligand capture, and can be used for research on critical illnesses including hypovolemia, liver failure, severe sepsis and various types of trauma resuscitation .

HY-W075903

Hexaamminecobalt(III) chloride Cobalt hexammine trichloride; Hexaamminecobalt trichloride	Biochemical Assay Reagents SOD Glutathione S-transferase	Metabolic Disease Cancer
Hexaamminecobalt (III) chloride is an orally active cobalt coordination compound. Hexaamminecobalt (III) chloride restores the activities of liver antioxidant enzymes (SOD, Catalase) and detoxification enzyme GST. Hexaamminecobalt (III) chloride restores GSH content and reduces DAG. Hexaamminecobalt (III) chloride impairs renal function. Hexaamminecobalt (III) chloride exerts anti-carcinogenic effects in Diethylnitrosamine (HY-N7434)-induced hepatocarcinoma .

HY-P2740

Alcohol dehydrogenase, Saccharomyces cerevisiae EC 1.1.1.1	Endogenous Metabolite	Metabolic Disease
Alcohol dehydrogenase, Saccharomyces cerevisiae is a dimeric protein in the cytosol of cells. Alcohol dehydrogenase, the key enzyme for alcohol consumption in the body, is the highest expressed in the liver and participates in the detoxification mechanism of environmental alcohol .

HY-P2961

Glutathione S-transferase	Glutathione S-transferase	Cancer
Glutathione S-transferase is a phase II metabolic enzyme consisting of three superfamilies: cytosolic, mitochondrial, and microsomal. Glutathione S-transferase possesses various catalytic activities such as catalytic detoxification and thiol transfer, as well as chaperone function. GSTP1, a subtype of Glutathione S-transferase, is highly expressed in malignant tissues and serves as a tumor marker .

HY-167920

Glutathione sulfonate S-Sulfoglutathione	Endogenous Metabolite	Cancer
Glutathione sulfonate (S-Sulfoglutathione) is a multifunctional bioactive compound that inhibits angiogenesis and tumor growth. Glutathione sulfonate is a competitive inhibitor of glutathione S-transferase and is involved in the detoxification process and the binding of a variety of exogenous and endogenous compounds. Glutathione sulfonate acts in the substrate binding site of Escherichia coli glutathione S-transferase, affecting the catalytic mechanism. The structural characteristics of Glutathione sulfonate contribute to its inhibitory effect by hydrogen bonding in the active center of the enzyme .

HY-P2774

Glyoxalase I Glo-I	Glycosidase	Inflammation/Immunology Cancer
Glyoxalase I (Glo-I) is a glycosidase and a methylglyoxal (MOG) detoxification enzyme. Glyoxalase I can be used for the research of inflammation and cancer .

HY-E70418

Epoxide hydrolase	Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology
Epoxide hydrolase is an enzyme responsible for catalyzing the reaction between epoxides and water, converting epoxide groups into diols. Epoxide hydrolase plays a key role in the metabolism of environmental pollutants and lipids, contributing to detoxification, inflammation responses, and the regulation of cardiovascular system health. Additionally, epoxide hydrolase can be used in asymmetric catalytic reactions, such as the asymmetric ring-opening of epoxides, to produce chiral drug molecules .

HY-115772

4′-Bromoflavone	Quinone Reductase	Cancer
4′-Bromoflavone, a cancer chemopreventive agent, is a potent phase II detoxification enzymes inducer .

HY-N10344

Glucoarabin	Cytochrome P450 Quinone Reductase	Cancer
Glucoarabin is a bioactive glucosinolate. In Hepa1c1c7 cells, hydrolyzed Glucoarabin (hGSL 9) upregulates the phase II detoxification enzyme quinone reductase (NQO1), with no effect on cytochrome P450 (CYP) 1A1 activity .

HY-W714675

Glucoiberin	Endogenous Metabolite	Cancer
Glucoiberin is a glucosinolate found in Brassica oleracea. Hydrolysis products of Glucoiberin exhibit anticancer activity .

HY-W099540

OES2-0017	Bacterial	Infection
OES2-0017 shows potent synergy with polyamines and growth-inhibitory effects at the low micromolar range. OES2-0017 inhibits spermine/spermidine acetyltransferase (SpeG) (IC₅₀: 34.82 μM ) and other polyamine detoxification enzymes in low concentrations, perturbed the bacterial membrane in higher concentrations .

HY-N6802

Tigloylgomisin H	Keap1-Nrf2	Cancer
Tigloylgomisin H is a lignan isolated from the fruits of S. chinensis, can induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarcinoma cells. Tigloylgomisin H functions as a monofunctional inducer that specifically upregulates phase II detoxification enzyme NQO1 through the NF-E2-related factor 2 (Nrf2)-ARE pathway, thus represents a potential liver cancer prevention agent .

HY-N0548R

α-Angelica lactone (Standard)	Glutathione S-transferase Reference Standards	Cancer
α-Angelica lactone (Standard) is the analytical standard of α-Angelica lactone. This product is intended for research and analytical applications. α-Angelica lactone is a naturally occurring anticarcinogen and an vinylogous nucleophile. α-Angelica lactone can give the chiral δ-amino γ,γ-disubstituted butenolide carbonyl derivatives and exhibitselectrophilic trapping at the γ-carbon. α-Angelica lactone exerts strong chemoprotective effects by selective enhancement of glutathione-S-thansferase (GST) and UDP-glucononosyltransferase (UGT) detoxification enzymes .

HY-P2864

Rhodanese	Biochemical Assay Reagents	Metabolic Disease
Rhodanese is the detoxification enzyme in sulfur metabolism for cyanide detoxification. Rhodanese is a mitochondrial protein .

HY-132178

Cytochrome P450	Endogenous Metabolite	Metabolic Disease Cancer
Cytochrome P450 is a family of monooxygenase enzymes that catalyzes the conversion of fatty acids to terminal alkenes using hydrogen peroxide as a cosubstrate. Cytochrome P450 as membrane-bound hemoproteins, plays important roles in the detoxification of drugs, cellular metabolism, and homeostasis .

HY-N17272

Cholic acid 3-sulfate	Drug Metabolite	Metabolic Disease
Cholic acid 3-sulfate is the sulfated metabolite of Cholic acid (HY-N0324), produced by liver enzyme sulfotransferase-2A1. Cholic acid 3-sulfate is less toxic than the parent compound, thus serving as a detoxification pathway for bile acids. Cholic acid 3-sulfate does not have the effect of stimulating intestinal secretion .

Cat. No.	Product Name	Type

HY-150097

Recombinant Human Serum Albumin(rHSA)	Biochemical Assay Reagents
Recombinant Human Serum Albumin (rHSA) is a non-glycosylated monomeric plasma protein that acts as a core factor for maintaining plasma colloid osmotic pressure. Recombinant Human Serum Albumin (rHSA) possesses multiple physiological functions including carrier, metabolic regulation, detoxification, antioxidation and enzyme mimicking. Recombinant Human Serum Albumin (rHSA) not only scavenges reactive oxygen and nitrogen species via specific residues and binds a variety of endogenous and exogenous compounds to maintain redox homeostasis, but also serves as a biomarker for multiple diseases such as cancer and inflammation. Recombinant Human Serum Albumin (rHSA) broadly supports the development of implantable materials, surgical adhesives and ligand capture, and can be used for research on critical illnesses including hypovolemia, liver failure, severe sepsis and various types of trauma resuscitation .

Recombinant Human Serum Albumin(rHSA)

Biochemical Assay Reagents

Recombinant Human Serum Albumin (rHSA) is a non-glycosylated monomeric plasma protein that acts as a core factor for maintaining plasma colloid osmotic pressure. Recombinant Human Serum Albumin (rHSA) possesses multiple physiological functions including carrier, metabolic regulation, detoxification, antioxidation and enzyme mimicking. Recombinant Human Serum Albumin (rHSA) not only scavenges reactive oxygen and nitrogen species via specific residues and binds a variety of endogenous and exogenous compounds to maintain redox homeostasis, but also serves as a biomarker for multiple diseases such as cancer and inflammation. Recombinant Human Serum Albumin (rHSA) broadly supports the development of implantable materials, surgical adhesives and ligand capture, and can be used for research on critical illnesses including hypovolemia, liver failure, severe sepsis and various types of trauma resuscitation .

HY-W075903

Hexaamminecobalt(III) chloride Cobalt hexammine trichloride; Hexaamminecobalt trichloride	Biochemical Assay Reagents
Hexaamminecobalt (III) chloride is an orally active cobalt coordination compound. Hexaamminecobalt (III) chloride restores the activities of liver antioxidant enzymes (SOD, Catalase) and detoxification enzyme GST. Hexaamminecobalt (III) chloride restores GSH content and reduces DAG. Hexaamminecobalt (III) chloride impairs renal function. Hexaamminecobalt (III) chloride exerts anti-carcinogenic effects in Diethylnitrosamine (HY-N7434)-induced hepatocarcinoma .

Hexaamminecobalt(III) chloride

Cobalt hexammine trichloride; Hexaamminecobalt trichloride

Biochemical Assay Reagents

Hexaamminecobalt (III) chloride is an orally active cobalt coordination compound. Hexaamminecobalt (III) chloride restores the activities of liver antioxidant enzymes (SOD, Catalase) and detoxification enzyme GST. Hexaamminecobalt (III) chloride restores GSH content and reduces DAG. Hexaamminecobalt (III) chloride impairs renal function. Hexaamminecobalt (III) chloride exerts anti-carcinogenic effects in Diethylnitrosamine (HY-N7434)-induced hepatocarcinoma .

DL-Menthol Racementhol	Structural Classification Natural Products Classification of Application Fields Leguminosae Labiatae Other Diseases Erythrina poeppigiana Plants Glycyrrhiza uralensis Fisch. Disease Research Fields Source Classification	Environmental Pollutants GABA Receptor
DL-Menthol (Racementhol) is an orally active, GABA_aR positive allosteric modulator and UDP-glucuronosyltransferase (UGT) inhibitor that can cross the blood-brain barrier. DL-Menthol binds to GABA_AR and exhibits an allosteric activation effect, enhancing GABA-mediated chloride influx and inhibiting neuronal excitability. DL-Menthol can induce surgical anesthesia in fish and inhibit the metabolic detoxification of tobacco carcinogens by human liver and intestinal UGT enzymes, resulting in reduced NNAL-N-Gluc production .

α-Angelica lactone 2 Publications Verification	Natural Products Classification of Application Fields Dicerothamnus rhinocerotis Umbelliferae Plants Disease Research Fields Source Classification Cancer	Glutathione S-transferase
α-Angelica lactone is a naturally occurring anticarcinogen and an vinylogous nucleophile. α-Angelica lactone can give the chiral δ-amino γ,γ-disubstituted butenolide carbonyl derivatives and exhibitselectrophilic trapping at the γ-carbon. α-Angelica lactone exerts strong chemoprotective effects by selective enhancement of glutathione-S-thansferase (GST) and UDP-glucononosyltransferase (UGT) detoxification enzymes .

Glucoarabin	Natural Products Classification of Application Fields Camelina sativa (L.) Crantz Glucosinolates Plants Brassicaceae Disease Research Fields Source Classification Cancer	Cytochrome P450 Quinone Reductase
Glucoarabin is a bioactive glucosinolate. In Hepa1c1c7 cells, hydrolyzed Glucoarabin (hGSL 9) upregulates the phase II detoxification enzyme quinone reductase (NQO1), with no effect on cytochrome P450 (CYP) 1A1 activity .

Glucoiberin	Structural Classification Iberis amara L. Plants Brassicaceae Saccharides Monosaccharides Source Classification	Endogenous Metabolite
Glucoiberin is a glucosinolate found in Brassica oleracea. Hydrolysis products of Glucoiberin exhibit anticancer activity .

Tigloylgomisin H	Classification of Application Fields Lignans Phenylpropanoids Plants Schisandraceae Schisandra chinensis (Turcz.) Baill. Disease Research Fields Source Classification Cancer	Keap1-Nrf2
Tigloylgomisin H is a lignan isolated from the fruits of S. chinensis, can induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarcinoma cells. Tigloylgomisin H functions as a monofunctional inducer that specifically upregulates phase II detoxification enzyme NQO1 through the NF-E2-related factor 2 (Nrf2)-ARE pathway, thus represents a potential liver cancer prevention agent .

α-Angelica lactone (Standard)	Structural Classification Natural Products Dicerothamnus rhinocerotis Umbelliferae Plants Source Classification	Glutathione S-transferase Reference Standards
α-Angelica lactone (Standard) is the analytical standard of α-Angelica lactone. This product is intended for research and analytical applications. α-Angelica lactone is a naturally occurring anticarcinogen and an vinylogous nucleophile. α-Angelica lactone can give the chiral δ-amino γ,γ-disubstituted butenolide carbonyl derivatives and exhibitselectrophilic trapping at the γ-carbon. α-Angelica lactone exerts strong chemoprotective effects by selective enhancement of glutathione-S-thansferase (GST) and UDP-glucononosyltransferase (UGT) detoxification enzymes .

Cytochrome P450	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Cytochrome P450 is a family of monooxygenase enzymes that catalyzes the conversion of fatty acids to terminal alkenes using hydrogen peroxide as a cosubstrate. Cytochrome P450 as membrane-bound hemoproteins, plays important roles in the detoxification of drugs, cellular metabolism, and homeostasis .

Cholic acid 3-sulfate	Structural Classification Endogenous metabolite Steroids Source Classification	Drug Metabolite
Cholic acid 3-sulfate is the sulfated metabolite of Cholic acid (HY-N0324), produced by liver enzyme sulfotransferase-2A1. Cholic acid 3-sulfate is less toxic than the parent compound, thus serving as a detoxification pathway for bile acids. Cholic acid 3-sulfate does not have the effect of stimulating intestinal secretion .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Name
Email *

	Sorry, but the email address you supplied was invalid.

detoxification enzyme

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Natural
Products