Glutathione S-transferase
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Glutathione S-transferase is a phase II metabolic enzyme composed of three superfamilies: cytosolic, mitochondrial, and microsomal. Glutathione S-transferase possesses multiple catalytic activities, including catalytic detoxification and thiol transfer, as well as molecular chaperone functions. The Glutathione S-transferase isoform GSTP1 is highly expressed in malignant tumors and serves as a tumor biomarker.
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- CAS No.: 50812-37-8
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
In Vitro
Glutathione S-transferase catalyzes the conjugation of the tripeptide glutathione with various reactive electrophilic species, including carcinogens, environmental pollutants, and byproducts of oxidative stress[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
EC Number
2.5.1.18
Specific Activity
≥25 U/,mg protein
Unit Definition
One unit is defined as the amount of enzyme that will conjugate 1.0 μmole of 1-chloro-2,4- dinitrobenzene with reduced glutathione per min at pH 6.5 at 25°C.
Chemical Information
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CAS No. 50812-37-8
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Appearance Solid
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Color White to off-white
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SMILES
[Glutathione S-transferase]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
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Fiche technique (264 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)