50812-37-8
50812-37-8
Chemical Structure
Glutathione S-transferase
- CAS No.: 50812-37-8
- Formula:N/A
- Molecular Weight:N/A
SMILES: [Glutathione S-transferase]
Biological Activity: Glutathione S-transferase is a phase II metabolic enzyme composed of three superfamilies: cytosolic, mitochondrial, and microsomal. Glutathione S-transferase possesses multiple catalytic activities, including catalytic detoxification and thiol transfer, as well as molecular chaperone functions. The Glutathione S-transferase isoform GSTP1 is highly expressed in malignant tumors and serves as a tumor biomarker[1][2].
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Glutathione S-transferase | Glutathione S-transferase is a phase II metabolic enzyme composed of three superfamilies: cytosolic, mitochondrial, and microsomal. Glutathione S-transferase possesses multiple catalytic activities, including catalytic detoxification and thiol transfer, as well as molecular chaperone functions. The Glutathione S-transferase isoform GSTP1 is highly expressed in malignant tumors and serves as a tumor biomarker. | |||||||||||||||||||||
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References
- [1]. Niitsu Y, et al. Implications of glutathione-S transferase P1 in MAPK signaling as a CRAF chaperone: In memory of Dr. Irving Listowsky. Proc Jpn Acad Ser B Phys Biol Sci. 2022;98(2):72-86. [Content Brief]
- [2]. Padhan P, et al. Glutathione S-transferase: A keystone in Parkinson's disease pathogenesis and therapy. Molecular and cellular neurosciences. 2025 Mar;132:103981.
